[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505883":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":34,"locations":39,"responsibleParty":72,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":18,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":18,"enrollmentInfo":89,"targetDuration":18,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":18,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Massachusetts Eye and Ear Infirmary","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Performance Assessed with Experimental Sound Processing Strategy","EXPERIMENTAL","Patients listening to experimental cochlear implant processing strategy.",[13],"Other: Experimental Speech Processing Strategy",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Patients listening to their clinical cochlear implant using their \"own\" processor (their everyday listening situation).",null,{"label":20,"type":21,"description":22,"interventionNames":23},"Experimental Control","SHAM_COMPARATOR","Patients listening to experimental cochlear implant using a processing strategy like thier clinical program, a \"clinical like\" program.",[13],[25],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":18},"Experimental Speech Processing Strategy","Patient's will listen with an experimental speech processor, programmed with a dynamic focusing strategy.",[20,9],[30],{"name":31,"affiliation":32,"role":33},"Julie Arenberg","Massachusetts Eye and Ear","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":18,"email":38},"CONTACT","617-807-7904","julie_arenberg@meei.harvard.edu",[40,57],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Mass Eye and Ear","RECRUITING","Boston","Massachusetts","02114","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-71.05977,42.35843,{"lat":52,"lon":51},[55,56],{"name":31,"role":36,"phone":37,"phoneExt":18,"email":38},{"name":31,"role":33,"phone":18,"phoneExt":18,"email":18},{"facility":58,"status":42,"city":59,"state":44,"zip":60,"country":46,"countryCode":47,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Boston Children's Hospital","Waltham","02453",{"type":49,"coordinates":62},[63,64],-71.23561,42.37649,{"lat":64,"lon":63},[67,71],{"name":68,"role":36,"phone":69,"phoneExt":18,"email":70},"Amanda Griffin","781-216-3657","amanda.griffin@childrens.harvard.edu",{"name":68,"role":33,"phone":18,"phoneExt":18,"email":18},{"type":33,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Julie G. Arenberg, CCC-A","Director of Research and Education",[76,77],{"name":58,"class":6},{"name":78,"class":6},"University of Washington","100505883","perceptual-consequences-of-cochlear-implant-electrode-neuron-interfaces-100505883",false,"NCT05867173","Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces","Development and Assessment of Listener-tailored Programming for Cochlear Implant Listeners","Inclusion Criteria:\n\nResearch Subjects with a Cochlear Implant ADULTS Inclusion Criteria\n\n* Adult at least 18 years old\n* Native speakers of American English\n* Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer), Cochlear, or MED-EL\n\nCHILDREN Inclusion Criteria\n\n* Children at least 3 months old\n* Native speakers of American English\n* Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer), Cochlear, or MED-EL\n\n  * For both children and adults with a cochlear implant, some study criteria might pertain to a subset of subjects, such as a specific age at which the subjects developed a hearing loss, or was implanted.\n\nExclusion Criteria:\n\nExclusion for all Cochlear Implant Subjects:\n\n* Inability to provide informed consent\n* Does not meet the inclusion criteria for a specific study protocol, such as age of onset of hearing loss, age of cochlear implantation, duration of deafness, number of active electrodes in the cochlear implant device\n* Unable to carry out the study protocol or tasks required in the study\n\nExclusion for all Normal Hearing Subjects:\n\n* Inability to provide informed consent\n* Hearing loss, or significant history of hearing related issues\n* Unable to carry out the study protocol or tasks required in the study",true,"ALL","3 Months",{"count":90,"type":91},200,"ESTIMATED","INTERVENTIONAL",[94],"NA","Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and adults who receive them. The main goals of this project are: i) to improve our understanding of how cochlear implants affect the developing auditory system, ii) apply that knowledge to test new methods for programming children and adults, and iii) to study how long it takes listeners to adapt to new cochlear implant programs over the short- and long-term. The results will improve our understanding of how the deafened auditory system develops with cochlear implant stimulation and advance clinical practice to improve hearing outcomes in cochlear implant listeners.",[97],"Deafness","2025-11-25",{"date":100,"type":101},"2025-11-26","ACTUAL",{"date":103,"type":101},"2022-09-16",{"date":105,"type":91},"2027-03-31",{"name":5,"class":6},2]