[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574317":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":44,"locations":52,"responsibleParty":67,"collaborators":30,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":30,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":30,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":30,"overallStatus":55,"whyStopped":30,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Cairo University","OTHER",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"non linear periodization exercise + medical treatment","EXPERIMENTAL","It will consist of 25 females, who will receive non linear periodization exercise in addition to their medical treatment.",[13,14],"Other: non linear periodization exercise","Drug: medical treatment",{"label":16,"type":10,"description":17,"interventionNames":18},"linear periodization exercise + medical treatment","It will consist of 25 females, who will receive linear periodization exercise in addition to their medical treatment.",[19,14],"Other: linear periodization exercise",{"label":21,"type":22,"description":23,"interventionNames":24},"medical treatment","ACTIVE_COMPARATOR","It will consist of 25 females, who will receive their medical treatment only.",[14],[26,31,35],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"non linear periodization exercise","The non-linear periodized resistance training program follows a 12-week schedule with varying intensity levels across three training days per week. The intensity fluctuates between very light (VL), light (L), moderate (M), heavy (H), and very heavy (VH) workouts, distributed strategically throughout the week. Each training day implements different intensity levels, and an active rest day follows any workout session.",[9],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"linear periodization exercise","The linear periodization exercise program spans 12 weeks with systematically varied training parameters. During weeks 1-2, participants perform 3 sets of 10 repetitions, followed by 3 sets of 8 repetitions in weeks 3-4. The program progresses to 4 sets of 6 repetitions in weeks 5-6, then 3 sets of 6 repetitions during weeks 7-8. The final phases consist of 4 sets of 4 repetitions in weeks 9-10, concluding with 3 sets of 4 repetitions in weeks 11-12. Training loads advance through autoregulatory progression, where participants progress at their individual pace under supervision. While sets and repetitions remain fixed within each phase, load progression is determined by performance in the final set of each exercise, ensuring safe and effective advancement.",[16],{"type":36,"name":21,"description":37,"armGroupLabels":38,"otherNames":30},"DRUG","The medical treatment will be received for 12 weeks.",[16,21,9],[40],{"name":41,"affiliation":42,"role":43},"Nesreen Gharib Mohamed Elnahas, PhD","Professor, Cairo university","STUDY_CHAIR",[45,50],{"name":46,"role":47,"phone":48,"phoneExt":30,"email":49},"Mona Mahmoud Mohamed Abd Elhady, M.Sc","CONTACT","01127744248","dmonamahmoud925@gmail.com",{"name":51,"role":47,"phone":30,"phoneExt":30,"email":30},"Salma Ibrahim Al Ghitany, PhD",[53],{"facility":54,"status":55,"city":56,"state":30,"zip":30,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Suez University","RECRUITING","Suez","Egypt","EG",{"type":60,"coordinates":61},"Point",[62,63],32.52627,29.97371,{"lat":63,"lon":62},[66],{"name":46,"role":47,"phone":48,"phoneExt":30,"email":49},{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Mona Mahmoud Mohamed Abd elhady","Principal Investigator","100574317","periodization-resistance-training-on-quality-of-life-in-females-with-hypothyroidism-100574317",false,"NCT06757712","Periodization Resistance Training on Quality of Life in Females With Hypothyroidism","Nonlinear Versus Linear Periodized Resistance Training on Quality of Life in Females With Hypothyroidism","Inclusion Criteria:\n\n* Be controlled hypothyroidism (TSH level within 0.5 - 4.5 mU\u002FL)\n* Be ranged from 35 to 45 years\n* Female patients\n* Body Mass Index 30-34.9 kg\u002Fm2 .\n* triglyceride-glucose (TyG) index \\> 4.5\n\nExclusion Criteria:\n\n* history of pulmonary disease\n* Patients with uncontrolled coronary or cerebrovascular disease\n* Those who underwent musculoskeletal surgery within the previous year\n* Recent history of lower and upper limb fracture , hip and shoulder dislocation.\n* Cognitive impaired patients\n* Patients with history of epilepsy\n* Patients who participating in any other exercise program","FEMALE","35 Years","45 Years",{"count":82,"type":83},75,"ESTIMATED","INTERVENTIONAL",[86],"NA","This study will be conducted to compare between the effect of nonlinear and linear periodized training on quality of life in females with hypothyroidism.",[89],"Hypothyroidism","2025-09-07",{"date":92,"type":93},"2025-09-12","ACTUAL",{"date":95,"type":93},"2025-01-01",{"date":97,"type":83},"2025-10-15",{"name":5,"class":6},1]