[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629249":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":24,"responsibleParty":35,"collaborators":24,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":24,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":67,"whyStopped":24,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":24},{"fullName":5,"class":6},"Saglik Bilimleri Universitesi","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ora-aid side","EXPERIMENTAL","A split-mouth study design has been planned for the same patient. The patient's right or left upper and lower jaws will be covered with Ora-Aid or periodontal paste after initial periodontal treatment. Which side will receive Ora-Aid and which side will receive periodontal paste will be determined by a coin toss. After full mouth scaling and root planing in the same session, Ora-Aid wound dressing or periodontal pat will be applied to the 1st and 3rd quadrants. Patients will be given oral hygiene instructions and asked to avoid brushing the periodontal dressing area while the dressings are in place. The wound dressings will be removed after 1 week.",[13],"Procedure: Coe-Pack application",{"label":15,"type":10,"description":11,"interventionNames":16},"Coe-pack side",[17],"Procedure: Ora Aid application",[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Ora Aid application","Baseline: Comprehensive periodontal measurements (GI, PI, PBI, BOP, PPD, and CAL) will be recorded. Subgingival plaque samples will be collected from the deepest periodontal pockets for microbiological analysis.\n\nIntervention: Following full-mouth scaling and root planing (SRP), Ora-Aid or Coe-Pak dressings will be applied to the designated quadrants.\n\n1-Week Follow-up: Periodontal dressings will be professionally removed from all treated sites.\n\n1-Month Follow-up: Periodontal clinical indices will be re-evaluated. Plaque samples will be collected from the same initial sites to determine changes in total bacterial load via qPCR.\n\n3-Month Follow-up: Final periodontal clinical measurements will be recorded to assess long-term treatment efficacy and clinical attachment gains.",[15],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Coe-Pack application","Baseline: Comprehensive periodontal measurements (GI, PI, PBI, BOP, PPD, and CAL) will be recorded. Subgingival plaque samples will be collected from the deepest periodontal pockets for microbiological analysis.\n\nIntervention: Following full-mouth scaling and root planing (SRP), Ora-Aid or Coe-Pak dressings will be applied to the designated quadrants.\n\n1-Week Follow-up: Periodontal dressings will be professionally removed from all treated sites.\n\n1-Month Follow-up: Periodontal clinical indices will be re-evaluated. Plaque samples will be collected from the same initial sites to determine changes in total bacterial load via qPCR.\n\n3-Month Follow-up: Final periodontal clinical measurements will be recorded to assess long-term treatment efficacy and clinical attachment gains",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"SEVAL CEYLAN ŞEN, Assist Prof","CONTACT","+905333161232","dt.sceylan@hotmail.com",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","SEVAL CEYLAN ŞEN","Assistant Professor","100629249","periodontal-dressings-in-non-surgical-therapy-100629249",false,"NCT07472218","Periodontal Dressings in Non-Surgical Therapy","Comparison of the Effectiveness of Two Different Periodontal Wound Dressings in Non-Surgical Periodontal Therapy","Inclusion Criteria:\n\n1. Systemically healthy volunteers aged 18-45 years.\n2. Diagnosis of Periodontitis (Stage 3, Grade A).\n3. Presence of at least 20 permanent teeth.\n4. Capacity to understand the study protocol and provide informed consent.\n\nExclusion Criteria:\n\n1. Systemic diseases (e.g., Diabetes, Chronic Renal Failure, Cancer, Connective Tissue Disorders).\n2. Pregnancy or breastfeeding.\n3. Smoking (\\>10 cigarettes\u002Fday).\n4. Antibiotic use within the last 3 months or periodontal treatment within the last year.\n5. Presence of orthodontic appliances, removable prostheses, or extensive interproximal caries.","ALL","18 Years","60 Years",{"count":50,"type":51},25,"ESTIMATED","INTERVENTIONAL",[54],"NA","This study aims to evaluate and compare the efficacy of two different eugenol-free periodontal dressing materials-Ora-Aid (a hydrophilic polymer) and Coe-Pak (a zinc oxide-based paste)-following non-surgical periodontal treatment (scaling and root planing, SRP) in patients with Stage 3, Grade A periodontitis. The study utilizes a split-mouth design to analyze clinical periodontal parameters, patient comfort, and microbiological changes over a 3-month period.",[57,58,59],"Periodontitis","Periodontitis (Stage 3)","Periodontal Pocket",[61,62,63,64,65,66],"periodontitis","Non-surgical periodontal therapy","Periodontal dressing","Ora-Aid","Coe-Pak","total bacterial load","NOT_YET_RECRUITING","2026-03-13",{"date":70,"type":71},"2026-03-16","ACTUAL",{"date":73,"type":51},"2026-04-01",{"date":75,"type":51},"2026-10-01",{"name":5,"class":6}]