[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100417693":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":10,"locations":23,"responsibleParty":45,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"University of Aberdeen","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cases",null,"Patients for the case study group will be recruited from those hospitalized for acute myocardial infarction on the Cardiology Ward and Coronary Care Unit at Aberdeen Royal Infirmary. All patients will be diagnosed using current clinical criteria for type-1 myocardial infarction according to the ESC guidelines10 and recruited within 3 days of admission. Recruitment of this arm is now complete.",[13],"Other: Full-mouth periodontal examination using computerised Florida probe",{"label":15,"type":10,"description":16,"interventionNames":17},"Controls","A control group of dental patients matched for age (±3 years), gender, and risk factors for CAD (hypertension, obesity, diabetes, smoking, hypercholesterolaemia and family history) but with no history of myocardial infarction will be selected at Aberdeen Dental School or from the SHARE register or via the NHS Research Scotland Primary Care Network on an invitation basis. Thr recruitment of this arm of the study is ongoing.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Full-mouth periodontal examination using computerised Florida probe","It is an observational study to investigate the prevalence of periodontitis in cases and controls.",[9,15],[24],{"facility":25,"status":26,"city":27,"state":10,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Dr Karolin Hijazi","RECRUITING","Aberdeen","AB25 2ZR","United Kingdom","UK",{"type":32,"coordinates":33},"Point",[34,35],-2.09814,57.14369,{"lat":35,"lon":34},[38,43],{"name":39,"role":40,"phone":41,"phoneExt":10,"email":42},"Karolin Hijazi, DDS, PhD","CONTACT","+441224555153","k.hijazi@abdn.ac.uk",{"name":39,"role":44,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":46,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100417693","periodontal-health-in-patients-acutely-admitted-for-myocardial-infarction-a-case-control-study-100417693",false,"NCT04719026","PERIODONTAL HEALTH IN PATIENTS ACUTELY ADMITTED FOR MYOCARDIAL INFARCTION: A CASE CONTROL STUDY","PEDICAD","Inclusion Criteria:\n\n* cases: Patients aged 20-90 admitted with acute myocardial infarction\n* controls: Dental patients, aged 20-90, matched to patients in the case study group for age, gender (±7) and risk factors for coronary artery disease (hypertension, obesity, diabetes, smoking, hypercholesterolaemia) but with no history of myocardial infarction)\n\nExclusion Criteria:\n\n* Severe co-morbidities, Inability to consent, pregnant participants will be excluded, participants with other systemic inflammatory diseases, patients taking antimicrobials or antibiotics in last three years, patients taking medications, such as cyclosporine, calcium channel blockers, phenytoin, immunocompromised patients, patients with malignancies, patinets with type-2 or type-3 hypersensitivities","ALL","20 Years","90 Years",{"count":58,"type":59},320,"ESTIMATED","OBSERVATIONAL","Heart attack remains a major cause of death in adult population worldwide and especially within Scotland. A large portion of the general population has an increased risk of suffering from a heart attack because of their genetic make-up, disease profile and lifestyle choices.\n\nLiterature suggests that apart from these known risk factors, long-standing inflammation (reaction of tissues to infection or injury) elsewhere in the body may be responsible for heart attacks. It has been suggested that gum disease may be one such condition. If left untreated, gum disease may expose the entire body to a long-term inflammatory burden where inflammatory molecules can disseminate from the gums into the bloodstream and affect various body structures. This study explores the influence of gum disease on the risk of heart attack by comparing the gum health of participants who recently had a heart attack to the gum health of participants with no history of heart problems after accounting for other risk factors. Findings will provide critical information for the design of our forthcoming study to establish the effect of treatment of gum disease on the risk of heart attack, and its cost-effectiveness. Ultimately this research will tackle another risk factor for heart attacks and thus inform enhancement of public health prevention strategies.",[63,64],"Myocardial Infarction, Acute","Periodontitis",[66,67,68],"myocardial infarction","coronary artery disease","periodontal diseases","2026-05-04",{"date":71,"type":72},"2026-05-08","ACTUAL",{"date":74,"type":72},"2018-02-16",{"date":76,"type":59},"2027-03-14",{"name":5,"class":6},1]