[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637468":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":34,"responsibleParty":51,"collaborators":55,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":12,"enrollmentInfo":69,"targetDuration":12,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":83,"whyStopped":12,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Beth Israel Deaconess Medical Center","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","In the control group, patients will receive standard of care anesthesia treatment, consisting of conventional preoxygenation and no active oxygen delivery during the apneic phase of induction. Following extubation, supplemental oxygen will be administered via face mask and subsequently weaned to standard nasal cannula as per routine clinical practice.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention","EXPERIMENTAL","In the intervention group, patients will receive high-flow nasal oxygen starting from induction of anesthesia until intubation, and from extubation until discharge from PACU with weaning of high-flow nasal oxygen during their PACU stay.",[18],"Device: High flow nasal oxygen",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"DEVICE","High flow nasal oxygen","In the intervention group, high-flow nasal oxygen (HFNO) will be initiated at the start of preoxygenation and maintained throughout the apneic phase of induction until successful tracheal intubation. HFNO will be reinitiated immediately prior to extubation and continued throughout the early postoperative period until discharge from the post-anesthesia care unit (PACU). HFNO can be discontinued earlier in the PACU at the discretion of the nurse treating the patient, or upon patient request. HFNO can further be changed to standard of care (standard oxygen mask or standard nasal cannula) at any time at the discretion of the anesthesia provider or PACU nurse. Flow rates and fraction of inspired oxygen (FiO₂) will follow the study protocol (60 liters per minute at 100% O2 for induction of anesthesia, 60 liters per minute at 70% O2 for extubation until 10 minutes after arrival in the PACU with subsequent weaning over the first hour after PACU arrival).",[14],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Arian Karimitar, PhD","CONTACT","6176328056","akarimit@bidmc.harvard.edu",{"name":32,"role":28,"phone":12,"phoneExt":12,"email":33},"Maximilian S. Schaefer, MD PhD","msschaef@bidmc.harvard.edu",[35],{"facility":5,"status":12,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Boston","Massachusetts","02215","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-71.05977,42.35843,{"lat":45,"lon":44},[48],{"name":49,"role":28,"phone":50,"phoneExt":12,"email":33},"Maximilian Schaefer Director, Center for Anesthesia Research Excellence, MD, PhD","+16173063216",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Maximilian S Schaefer","Associate Professor of Anaesthesia",[56],{"name":57,"class":58},"Fisher and Paykel Healthcare","INDUSTRY","100637468","perioperative-high-flow-nasal-oxygen-in-patients-undergoing-robotic-surgery-100637468",false,"NCT07591610","Perioperative High-flow Nasal Oxygen in Patients Undergoing Robotic Surgery","Perioperative High-flow Nasal Oxygen in Patients Undergoing Robotic Surgery: A Randomized Trial","Periop HFNO","Inclusion Criteria:\n\n* Age \\>= 18\n* Undergoing non-emergent, non-cardiac, intra-abdominal, intra-thoracic or pelvic robot-assisted surgery with an expected duration of at least 2 hours under general anesthesia with planned extubation at the end of the procedure\n\nExclusion Criteria:\n\n* Known pregnancy\n* Preoperative intubation or tracheostomy\n* Anatomical or clinical conditions precluding the use of high-flow nasal oxygen (severe midface trauma, recent nasal surgery, severe nasal septum deviation, severe nasal deformation)\n* Contraindications to electrical impedance tomography (EIT), including inability to place the EIT belt or presence of active implantable electronic devices (e.g., pacemaker or implantable cardioverter-defibrillator)\n* Planned postoperative admission to the intensive care unit","ALL","18 Years",{"count":70,"type":71},190,"ESTIMATED","INTERVENTIONAL",[74],"NA","The aim of the study is to assess whether perioperative use of high-flow nasal oxygen (HFNO) during the period from induction of anesthesia until discharge from the post-anesthesia care unit in patients undergoing robotic-assisted surgery reduces perioperative oxygen desaturation and postoperative pulmonary complications.",[77],"Robotic Surgery",[79,80,81,82],"Electric Impedance Tomography (EIT)","High-flow nasal oxygenation","Perioperative oxygenation","Robotic surgery","NOT_YET_RECRUITING","2026-06-01",{"date":86,"type":87},"2026-06-02","ACTUAL",{"date":89,"type":71},"2026-08-01",{"date":91,"type":71},"2029-10-31",{"name":5,"class":6},1]