[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642455":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":10,"locations":25,"responsibleParty":39,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Second Hospital of Jilin University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CABG Patients",null,"A prospective cohort of adult patients undergoing elective or urgent coronary artery bypass grafting. Participants will undergo perioperative evaluation including hs-troponin testing, ECG, echocardiography, and cardiac MRI to assess perioperative myocardial injury.",[13,14],"Diagnostic Test: High-Sensitivity Troponin","Diagnostic Test: Cardiac MRI",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","High-Sensitivity Troponin","High-sensitivity troponin levels are measured preoperatively, predischarge, and at 6-month follow-up to assess perioperative myocardial injury.",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Cardiac MRI","A diagnostic assessment panel including high-sensitivity troponin testing, electrocardiography, echocardiography, and cardiac magnetic resonance imaging performed during the perioperative period.",[9],[26],{"facility":27,"status":10,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":10},"the Second Hospital of Jilin University","Changchun","Jilin","130000","China","CN",{"type":34,"coordinates":35},"Point",[36,37],125.32278,43.88,{"lat":37,"lon":36},{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Kexiang Liu, MD","Principal Investigator","100642455","perioperative-myocardial-injury-in-patients-undergoing-coronary-artery-bypass-grafting-a-prospective-clinical-study-100642455",false,"NCT07650487","Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study","Prospective Clinical Study for Evaluation of Perioperative Myocardial Injury Using High-Sensitivity Troponin and Cardiac MRI in Patients Undergoing Coronary Artery Bypass Grafting (CABG)","Inclusion Criteria:\n\n1. Age ≥ 21 years\n2. Undergoing CABG for unstable angina\n3. Able to provide written informed consent\n4. No major cardiovascular event in the prior 6 months\n\nExclusion Criteria:\n\n1. Significant hepatic, renal, or other major organ dysfunction\n2. Pregnancy or breastfeeding\n3. Withdrawal during the study\n4. Contraindication to cardiac MRI (metal implants, claustrophobia, etc.)","ALL","21 Years","80 Years",{"count":54,"type":55},150,"ESTIMATED","OBSERVATIONAL","Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.",[59,60],"Myocardial Injury","Coronary Artery Disease",[62,63,22,64,60],"Perioperative Myocardial Injury","Coronary Artery Bypass Grafting","hs-Troponin","NOT_YET_RECRUITING","2026-06-10",{"date":68,"type":69},"2026-06-16","ACTUAL",{"date":71,"type":55},"2026-07-01",{"date":73,"type":55},"2027-07-30",{"name":5,"class":6},1]