[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544777":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":10,"responsibleParty":21,"collaborators":10,"id":23,"slug":24,"hasResults":25,"nctId":26,"briefTitle":27,"officialTitle":28,"acronym":29,"eligibilityCriteria":30,"healthyVolunteers":25,"sex":31,"minAge":32,"maxAge":33,"enrollmentInfo":34,"targetDuration":10,"studyType":37,"phases":10,"briefSummary":38,"conditions":39,"keywords":41,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":10},{"fullName":5,"class":6},"Norfolk and Norwich University Hospitals NHS Foundation Trust","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Exercise Therapy",null,"Patients who are advised by their clinician to undertake exercise therapy as their treatment for peripheral arterial disease",{"label":13,"type":10,"description":14,"interventionNames":10},"Angioplasty","Patients undergoing angioplasty for treatment of peripheral arterial disease, as advised by their clinician.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Phillip Stather","CONTACT","01603 286286","philip.stather@nnuh.nhs.uk",{"type":22,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100544777","peripheral-arterial-disease-biomarkers-100544777",false,"NCT06373302","Peripheral Arterial Disease Biomarkers","Peripheral Arterial Disease Biomarkers: The Effect of Intervention on Biomarker Levels and Predictors of Restenosis or Deterioration","PADBIRD","Inclusion Criteria:\n\n* Aged \\> 50 years\n* Symptomatic PAD\n* ABPI \\\u003C0.8 or TBPI \\\u003C0.7\n\nExclusion Criteria:\n\n* Aged \\\u003C50 years\n* Current Malignancy\n* Rheumatological Condition\n* Previous surgical or endovascular intervention for PAD\n* ABPI \\>0.8 or TBPI \\>0.7","ALL","50 Years","99 Years",{"count":35,"type":36},100,"ESTIMATED","OBSERVATIONAL","The study aims to determine how expression levels of biomarkers for peripheral arterial disease change over time in response to exercise therapy, surgical or endovascular intervention, and whether they can be used to predict disease progression.",[40],"Peripheral Arterial Disease",[42,43,44,45],"Peripheral","Arterial","Disease","Claudication","NOT_YET_RECRUITING","2024-04-17",{"date":49,"type":50},"2024-04-18","ACTUAL",{"date":52,"type":36},"2024-05-01",{"date":54,"type":36},"2026-12-31",{"name":5,"class":6}]