[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566565":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":18,"centralContacts":27,"locations":36,"responsibleParty":55,"collaborators":18,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":18,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Leipzig","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Randomised Arm 1: Heart Failure Network Care","EXPERIMENTAL","Patients will receive three follow-up visits during the vulnerable period (three month after hospital discharge) in the HF network (either cardiologist in private practice or HF outpatient clinic)",[13],"Other: Heart Failure network care",{"label":15,"type":16,"description":17,"interventionNames":18},"Randomised Arm 2: Usual care","NO_INTERVENTION","Patients will receive usual care by their primary physician or cardiologist",null,{"label":20,"type":16,"description":21,"interventionNames":18},"Registry Arm for non-randomised patients","Patients not willing to be randomised will be followed in a registry.",[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":18},"Heart Failure network care","Patients will receive three visits within the first three months after randomization for improving heart failure therapy at a cardiologist or the outpatient heart failure clinic",[9],[28,33],{"name":29,"role":30,"phone":31,"phoneExt":18,"email":32},"Rolf Wachter, MD","CONTACT","+49-341-97-12650","rolf.wachter@medizin.uni-leipzig.de",{"name":34,"role":30,"phone":31,"phoneExt":18,"email":35},"Sophie Charlotte Schröder, MD","sophiecharlotte.schroeder@medizin.uni-leipzig.de",[37],{"facility":38,"status":39,"city":40,"state":18,"zip":18,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"University Hospital Leipzig","RECRUITING","Leipzig","Germany","DE",{"type":44,"coordinates":45},"Point",[46,47],12.37129,51.33962,{"lat":47,"lon":46},[50,54],{"name":51,"role":30,"phone":52,"phoneExt":18,"email":53},"Charlotte Sophie Schröder, MD","+49 341 97 12650","SophieCharlotte.Schroeder@medizin.uni-leipzig.de",{"name":29,"role":30,"phone":18,"phoneExt":18,"email":32},{"type":56,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100566565","peripheral-drivers-of-heart-failure-progression---the-prospective-pedal-hf-study-100566565",false,"NCT06656832","Peripheral Drivers of Heart Failure Progression - The Prospective PEDAL-HF Study","PEDAL-HF","Inclusion Criteria:\n\n* Patients admitted to the participating study centres with acute decompensated heart failure (ADHF), defined as clinical signs and\u002For symptoms of heart failure\n* objective structural cardiac abnormalitites according to the ESC criteria.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* pregnancy\n* any condition interfering with the informed consent process\n* patients placed in an institution by official or court order","ALL","18 Years",{"count":67,"type":68},1000,"ESTIMATED","INTERVENTIONAL",[71],"NA","PEDAL-HF is a registry-based randomized prospective multicenter study. The investigators plan to include 1000 patients who were recently admitted with acute decompensated heart failure at five tertiary heart clinics in Germany. For the randomised part, 750 patients will be randomized to care within a heart failure network or usual care. The primary endpoint of the randomized trial is change in NT-proBNP from baseline to 6 months of follow-up.\n\nAll patients (randomized or not) will be followed for two years.",[74],"Heart Failure - NYHA II - IV",[76],"Heart Failure Network Care","2026-04-30",{"date":79,"type":80},"2026-05-06","ACTUAL",{"date":82,"type":80},"2024-11-28",{"date":84,"type":68},"2028-12-31",{"name":5,"class":6},1]