[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640925":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":43,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":68,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Region Stockholm","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients With Circulatory Shock",null,"Adult patients with clinical signs of circulatory shock or impending circulatory failure undergoing routine hemodynamic monitoring with non-invasive and\u002For invasive arterial blood pressure measurement during standard clinical care.",[13],"Procedure: Peripheral Pulse Palpation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Peripheral Pulse Palpation","Manual palpation of carotid, femoral, and radial pulses performed during routine clinical care in patients with circulatory instability. Simultaneous arterial blood pressure measurements are recorded from standard monitoring systems. No study-specific treatment or intervention is administered.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Mattias Günther, MD PhD","CONTACT","46812361000","mattias.gunther@ki.se",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Region Stockholm, all hospitals","RECRUITING","Stockholm","Stockholm County","11883","Sweden","SE",{"type":36,"coordinates":37},"Point",[38,39],18.06871,59.32938,{"lat":39,"lon":38},[42],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mattias Gunther","MD PhD Associate Professor","100640925","peripheral-pulse-assessment-and-arterial-pressure-pulsar-100640925",false,"NCT07609095","Peripheral pULSe Assessment and Arterial pRessure (PULSAR)","Association Between Palpable Peripheral Pulses and Arterial Blood Pressure in Patients With Circulatory Shock: An International Prospective Multicenter Observational Cohort Study","PULSAR","Inclusion Criteria:\n\n* Clinical signs of circulatory shock or impending circulatory failure\n* Availability of non-invasive and\u002For invasive arterial blood pressure monitoring\n* Pulse palpation possible without interfering with emergency care\n\nExclusion Criteria:\n\n* Peripheral vascular conditions preventing reliable pulse palpation\n* Major extremity amputation affecting assessment sites\n* Clinical situations where study procedures interfere with life-saving treatment","ALL","18 Years",{"count":58,"type":59},5000,"ESTIMATED","OBSERVATIONAL","This prospective multicenter observational study aims to investigate the relationship between palpable peripheral pulses and simultaneously measured arterial blood pressure in adult patients with circulatory shock or impending circulatory failure. Peripheral pulse palpation is routinely used in emergency medicine, trauma care, critical care, and cardiopulmonary resuscitation as a rapid clinical assessment of circulation. However, the association between palpable pulses and actual arterial blood pressure remains poorly validated.\n\nPatients treated in emergency departments, intensive care units, operating rooms, and other acute care settings will undergo routine pulse palpation at predefined anatomical locations including carotid, femoral, and radial arteries. Simultaneously measured non-invasive and\u002For invasive arterial blood pressure values will be recorded from routine clinical monitoring systems. Additional clinical variables relevant to circulatory status will also be collected.\n\nThe study seeks to define blood pressure thresholds associated with pulse palpability and evaluate the agreement between invasive and non-invasive blood pressure measurements in patients with circulatory shock.",[63,64,65,66,67],"Circulatory Shock","Hemodynamic Instability","Hypotension","Shock","Critical Illness",[63,69,70,71,72,65,73,74,75,64],"Hemodynamic Monitoring","Pulse Palpation","Peripheral Pulse","Arterial Blood Pressure","Critical Care","Trauma","Resuscitation","2026-05-19",{"date":78,"type":79},"2026-05-27","ACTUAL",{"date":81,"type":59},"2026-06-01",{"date":83,"type":59},"2031-12-31",{"name":5,"class":6},1]