[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545621":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":40,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Fluid challenge",null,"Impact of fluid challenge on peripheral tissue perfusion on sepsis patients",{"label":13,"type":10,"description":14,"interventionNames":10},"Vasopressors","Impact of vasopressors on peripheral tissue perfusion on sepsis patients",{"label":16,"type":10,"description":17,"interventionNames":10},"Inotrope","Impact of dobutamine on peripheral tissue perfusion on patients with septic or cardiogenic shock",[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Hafid Ait-Oufella","CONTACT","+33612011940","hafid.aitoufella@aphp.fr",[25],{"facility":26,"status":27,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Saint -Antoine Hospital_Médecine Intensive Reanimation","RECRUITING","Paris","75012","France","FR",{"type":33,"coordinates":34},"Point",[35,36],2.3488,48.85341,{"lat":36,"lon":35},[39],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},{"type":41,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100545621","peripheral-tissue-perfusion-in-intensive-care-100545621",false,"NCT06384287","Peripheral Tissue Perfusion in Intensive Care","Effects of Therapeutic Hemodynamic Interventions on Peripheral Perfusion in Intensive Care","INPPEREA","Inclusion Criteria:\n\n* Patients in intensive care unit with acute circulatory failure related to sepsis or cardiac failure requiring therapeutic intervention\n\nExclusion Criteria:\n\n* Agitation\n* Hemorrhagic shock\n* Severe skin lesions","ALL","18 Years",{"count":53,"type":54},180,"ESTIMATED","OBSERVATIONAL","Tissue perfusion has been identified as an early prognosis factor in patients admitted to intensive care. However, little is known about the effects of different hemodynamic interventions performed in clinical routine on peripheral tissue perfusion.\n\nThe aim of this work is to study the kinetics of CRT and local skin blood flow following therapeutic intervention (fluid challenge, vasopressor or inotropic drug).",[58],"Acute Circulatory Failure",[60,61,62,9,16],"Tissue perfusion","Capillary refill time","Skin blood flow","2025-08-25",{"date":65,"type":66},"2025-09-02","ACTUAL",{"date":68,"type":66},"2024-06-22",{"date":70,"type":54},"2027-07",{"name":5,"class":6},1]