[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629892":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":18,"responsibleParty":24,"collaborators":18,"id":28,"slug":29,"hasResults":30,"nctId":31,"briefTitle":32,"officialTitle":33,"acronym":34,"eligibilityCriteria":35,"healthyVolunteers":30,"sex":36,"minAge":37,"maxAge":38,"enrollmentInfo":39,"targetDuration":18,"studyType":42,"phases":43,"briefSummary":45,"conditions":46,"keywords":48,"overallStatus":55,"whyStopped":18,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":18},{"fullName":5,"class":6},"Sakarya Yenikent State Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Digital Reminder Intervention","EXPERIMENTAL","Participants receive a personalized mobile adherence program in addition to standard glaucoma care, including daily interactive SMS\u002FWhatsApp medication reminders and weekly brief educational messages for 3 months.",[13],"Behavioral: Digital Reminder Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Care","NO_INTERVENTION","Participants receive routine outpatient glaucoma follow-up and prescribed topical antiglaucoma treatment without digital reminders.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","A behavioral adherence support intervention consisting of daily interactive SMS\u002FWhatsApp reminders for eye-drop use and weekly educational reinforcement messages over 3 months.",[9],{"type":25,"investigatorFullName":26,"investigatorTitle":27,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Ali Altan Ertan Boz","Yenikent State Hospital, Head of Ophthalmology","100629892","personalized-mobile-reminders-for-medication-adherence-and-intraocular-pressure-control-in-primary-open-angle-glaucoma-100629892",false,"NCT07480577","Personalized Mobile Reminders for Medication Adherence and Intraocular Pressure Control in Primary Open-Angle Glaucoma","Effectiveness of a Personalized Mobile Reminder System on Medication Adherence and Intraocular Pressure Control in Primary Open-Angle Glaucoma: A Prospective, Parallel-Group, Randomized Controlled Trial","M-GLAUCO","Inclusion Criteria:\n\nAdults aged 18 to 75 years. Diagnosis of primary open-angle glaucoma (POAG) in at least one eye. Currently treated with at least one topical antiglaucoma medication. Able to read and understand study procedures and provide written informed consent.\n\nHas regular access to a mobile phone capable of receiving SMS or WhatsApp messages.\n\nWilling to comply with follow-up visits and study procedures for 3 month\n\nExclusion Criteria:\n\nSecondary glaucoma (e.g., neovascular, uveitic, steroid-induced) or angle-closure glaucoma.\n\nOcular surgery or laser procedure within the previous 3 months, or planned ocular surgery during study follow-up.\n\nAdvanced ocular comorbidity likely to affect IOP assessment or adherence evaluation (e.g., severe corneal disease, active ocular infection\u002Finflammation).\n\nCognitive impairment, severe psychiatric disease, or communication barriers that prevent reliable participation.\n\nInability to use or access mobile messaging tools required for the intervention.\n\nParticipation in another interventional clinical study that may interfere with outcomes","ALL","18 Years","75 Years",{"count":40,"type":41},84,"ESTIMATED","INTERVENTIONAL",[44],"NA","This study evaluates whether a personalized mobile reminder program improves treatment adherence and clinical outcomes in adults with primary open-angle glaucoma (POAG) using topical antiglaucoma eye drops. Poor adherence to long-term eye-drop therapy is common in glaucoma care and may contribute to inadequate intraocular pressure (IOP) control and disease progression.\n\nParticipants are randomized to either (1) a digital adherence intervention or (2) standard outpatient follow-up. The intervention consists of daily interactive SMS\u002FWhatsApp medication reminders plus weekly brief educational messages for 3 months. The primary outcome is change in medication adherence measured by the Morisky Medication Adherence Scale-8 (MMAS-8) at month 3. Secondary outcomes include change in IOP, eye-drop instillation technique, and treatment satisfaction. Exploratory analyses assess the relationship between adherence level and OCT-based retinal nerve fiber layer (RNFL) progression metrics. The goal is to determine whether a low-cost, scalable mobile strategy can improve short-term glaucoma management in routine practice.",[47],"Primary Open-Angle Glaucoma (POAG)",[49,50,51,52,53,54],"Primary Open-Angle Glaucoma","Medication Adherence","Mobile Reminder","SMS Reminder","WhatsApp Reminder","MMAS-8","NOT_YET_RECRUITING","2026-03-14",{"date":58,"type":59},"2026-03-18","ACTUAL",{"date":61,"type":41},"2026-04-01",{"date":63,"type":41},"2026-08-01",{"name":5,"class":6}]