[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595038":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":68,"collaborators":71,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":18,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":18,"enrollmentInfo":82,"targetDuration":18,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":95,"overallStatus":38,"whyStopped":18,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Seoul National University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"AVS + 68Ga-pentixafor PET\u002FCT (+ 11C-metomidate PET\u002FCT)","EXPERIMENTAL","Intervention:\n\nDiagnostic Imaging: 68Ga-pentixafor PET\u002FCT\n\nWith 68Ga-pentixafor PET\u002FCT imaging added to AVS for lateralization Subset only: 11C-metomidate PET\u002FCT (for research use only, not used in treatment decisions)",[13],"Diagnostic Test: 68Ga-pentixafor PET\u002FCT",{"label":15,"type":16,"description":17,"interventionNames":18},"AVS only","NO_INTERVENTION","No PET\u002FCT Without 68Ga-pentixafor PET\u002FCT imaging; AVS only (Gold standard)",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","68Ga-pentixafor PET\u002FCT","Diagnostic PET\u002FCT imaging using gallium-68 labeled pentixafor to assess adrenal CXCR4 expression in patients with primary aldosteronism. The imaging is performed prior to treatment allocation and used to assist lateralization of aldosterone production when combined with adrenal venous sampling (AVS).",[9],[26],{"name":27,"affiliation":5,"role":28},"Su-jin Kim, M.D, Ph.D","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Seungho Lee, M.D","CONTACT","82-10-8629-9209","ganymedes10@gmail.com",[36,56],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":18,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Samsung Medical Center","RECRUITING","Seoul","Gangnam-gu","06351","South Korea",{"type":44,"coordinates":45},"Point",[46,47],126.9784,37.566,{"lat":47,"lon":46},[50,54],{"name":51,"role":32,"phone":52,"phoneExt":18,"email":53},"You bin Lee, M.D, Ph.D","82-10-3176-7019","yb.snowyday1224@gmail.com",{"name":51,"role":55,"phone":18,"phoneExt":18,"email":18},"SUB_INVESTIGATOR",{"facility":5,"status":38,"city":39,"state":57,"zip":58,"country":42,"countryCode":18,"cosmosGeoPoint":59,"geoPoint":61,"contacts":62},"Jongno-gu","03080",{"type":44,"coordinates":60},[46,47],{"lat":47,"lon":46},[63,64,67],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},{"name":27,"role":32,"phone":65,"phoneExt":18,"email":66},"82-10-8509-7018","su.jin.kim.md@gmail.com",{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"type":28,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Su-jin Kim","Professor, Department of Surgery, Seoul National University Hospital",[72],{"name":37,"class":6},"100595038","petal-trial-impact-of-gallium-68-pentixafor-pet-ct-on-surgical-outcomes-in-primary-aldosteronism-100595038",false,"NCT07027254","PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism","A Randomized Controlled Trial to Evaluate the Effect of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Patients With Primary Aldosteronism (The PETAL Trial)","Inclusion Criteria:\n\n* Age ≥19 years\n* Diagnosed with PA per 2016 Endocrine Society guidelines\n* Underwent adrenal CT\n* Signed informed consent\n\nExclusion Criteria:\n\n* Women who are pregnant, breastfeeding, or may become pregnant\n* Individuals who refuse to undergo surgery\n* Individuals for whom 68Ga-Pentixafor PET\u002FCT, 11C-Metomidate PET\u002FCT, or adrenal venous sampling (AVS) is not feasible or is refused due to underlying conditions\n* Individuals who refuse or experience adverse effects from dexamethasone premedication required for 11C-Metomidate PET\u002FCT\n* Individuals with a history of abdominal open surgery or retroperitoneal surgery on the same side as the planned adrenalectomy\n* Any individual deemed unsuitable for the study at the discretion of the investigator","ALL","19 Years",{"count":83,"type":84},90,"ESTIMATED","INTERVENTIONAL",[87],"NA","This study is a randomized controlled trial to assess the clinical utility of gallium-68 pentixafor PET\u002FCT in the management of primary aldosteronism (PA). We aim to evaluate whether the addition of 68Ga-pentixafor PET\u002FCT to standard adrenal venous sampling (AVS) improves surgical outcomes in patients with unilateral PA.",[90,91,92,93,94],"Primary Aldosteronism","Secondary Hypertension","Aldosterone-Producing Adenoma","Idiopathic Hyperaldosteronism","Adrenalectomy",[96,97,98,99,100,101,102,94],"Primary aldosteronism","Gallium-68 pentixafor","11C-metomidate","PET\u002FCT","adrenal venous sampling","PASO","PAMO","2025-06-16",{"date":105,"type":106},"2025-06-18","ACTUAL",{"date":108,"type":84},"2025-06-25",{"date":110,"type":84},"2027-12-01",{"name":5,"class":6},2]