[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100521972":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":32,"responsibleParty":52,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":10,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of Texas Southwestern Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patient diagnosed with incidental solid renal mass",null,"All patients at our institution who are diagnosed with indeterminate solid SRM and without prior treatment for the tumor, renal biopsy or contraindication to PET\u002FMRI can be included in the study. This will be a prospective, non-randomized, non-blinded observational study. Patients will then be managed following the standard of care.",[13],"Diagnostic Test: 2-Deoxy-2-[18F]fluoroglucose Positron Emission Tomography\u002FMagnetic Resonance Imaging",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","2-Deoxy-2-[18F]fluoroglucose Positron Emission Tomography\u002FMagnetic Resonance Imaging","PET\u002FMR scan utilizing FDG Radiopharmaceutical",[9],[21],"FDG PET\u002FMR",[23],{"name":24,"affiliation":5,"role":25},"Ivan Pedrosa, MD, PhD","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"UTSW Radiology Clinical Research Office","CONTACT","214-645-1568","RCRO@utsouthwestern.edu",[33],{"facility":5,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Dallas","Texas","75390","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-96.80667,32.78306,{"lat":44,"lon":43},[47,51],{"name":48,"role":29,"phone":49,"phoneExt":10,"email":50},"Charlton C Starcke","214-648-7754","charlton.starcke@utsouthwestern.edu",{"name":24,"role":25,"phone":10,"phoneExt":10,"email":10},{"type":25,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Robert Sibley","Assistant Professor, Radiology",[56],{"name":57,"class":6},"Radiological Society of North America","100521972","petmr-for-characterization-of-renal-masses-rms-100521972",false,"NCT06076538","PET\u002FMR for Characterization of Renal Masses (RMs)","Prospective Observational Study Using PET\u002FMR for Characterization of Renal Masses (RMs)","Inclusion Criteria:\n\n* Patients with known solid (\\>25% total volume enhances) renal mass\n* Renal mass size measuring \\>2 to ≤7 cm\n* Age \\>18 years\n* Ability to understand and the willingness to sign a written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy\n* Prior percutaneous biopsy of the renal mass\n* Prior treatment of the renal mass\n* Prior hemorrhage in the renal mass\n* Contraindication to MRI or PET\n* Renal mass not eligible for ccLS based on prior imaging (i.e., containing macroscopic fat \\[classic angiomyolipoma\\] or enhancing less than 25% of its volume \\[considered a cystic renal mass\\])\n* Genetic syndrome predisposing to renal masses (e.g., VHL, BHD, TSC, etc.);\n* More than 3 renal masses at time of initial diagnosis","ALL","18 Years",{"count":68,"type":69},97,"ESTIMATED","OBSERVATIONAL","The frequency of kidney tumors found incidentally on imaging studies performed for unrelated reasons continues to increase leading to more surgeries and ablations for the treatment of renal masses thought to be cancer. However, about 20% of these masses are not cancerous and do not require treatment. Many cancerous kidney tumors are indolent and can be followed safely with imaging (i.e., particularly tumors \\\u003C2 cm and in patients with limited life expectancy), while some tumors are both malignant and aggressive, with a higher potential to spread outside the kidney and require treatment.\n\nThe purpose of this observational study is to assess the ability of Fludeoxyglucose (18F) (FDG) PET\u002FMR to distinguish different types of kidney tumors. The investigators hypothesize that PET\u002FMR will better show differences between aggressive and both indolent and benign kidney masses compared to the currently used radiologic scans.\n\nParticipants will be selected from those who have been scheduled to receive a contrast-enhanced MRI for their regular care due to a suspicious kidney mass. Participants will have their MRI on a hybrid PET\u002FMR scanner capable of obtaining both MRI and PET images. While they are receiving their standard of care MRI exam, patients will also receive a research FDG PET exam. Participants will have an IV placed for administration of the MRI contrast agent, just as they would if they were not taking part in the study. The same IV will be used to give the FDG radiopharmaceutical for the PET scan and furosemide (a diuretic), to help empty the bladder before the scan and help better see the kidneys on the scans. Both FDG and furosemide are FDA approved medications. Participants will have only one visit with the research team which will last \\~2.5 hours and will include collection of the participant's regularly scheduled MRI.\n\nIf participants undergo surgery to remove the tumor, the study will collect samples of the removed tissue for research. If participants receive a biopsy of the tumor, the study may collect an additional sample of the tumor for research.\n\nAfter the PET\u002FMRI, participants will not have additional visits with the study team, but the study team may call every 6-12 months for up to 2 years to see how they are doing and ask about their health. The study team will review the medical record for any changes to their diagnosis, updates to their medical history, new scans ordered by their regular doctor, or recent lab or biopsy results.",[73,74,75],"Renal Tumor","Renal Cell Carcinoma","Renal Tumor, Benign",[77,74,78],"Renal Mass","PET\u002FMR","2025-12-19",{"date":81,"type":82},"2025-12-29","ACTUAL",{"date":84,"type":82},"2023-08-01",{"date":86,"type":69},"2028-06-01",{"name":5,"class":6},1]