[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568432":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":32,"locations":40,"responsibleParty":58,"collaborators":12,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":12,"enrollmentInfo":69,"targetDuration":12,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":12,"overallStatus":43,"whyStopped":12,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Alberta","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Usual Care (Control) Group","NO_INTERVENTION","Pharmacists will provide a general educational pamphlet and will inform the primary care physician of patient participation and referral for further assessment of knee OA.\n\nParticipants randomized to this group will be offered physiotherapy and\u002For pharmacy interventions (individual or GLA:D program 3 months after enrollment) and pharmacy options (comprehensive medication review). It will be explained to participants that usual care is 'conservative therapy'.\n\nUsual care participants will be eligible to opt in for a comprehensive medication review (pharmacist) and\u002For the physiotherapy sessions and will be evaluated at 9-months after enrollment.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention Group","EXPERIMENTAL","Pharmacists will provide comprehensive 1:1 patient care, including a SCHOLAR assessment and medication review, provide specific drug therapy recommendation(s) using shared decision making (SDM), and provide comprehensive patient education\u002Fresources. Pharmacists will refer to physiotherapy clinics located nearby for patient convenience and to establish community pharmacy\u002Fphysiotherapy clinic relationships.\n\nParticipants will be offered a physiotherapy assessment at a nearby physiotherapy clinic within 2 weeks of being assessed by the pharmacist. After the physiotherapy assessment session, participants who are diagnosed with symptomatic knee OA will be offered the GLA:D program for knee OA which includes 6-weeks of neuromuscular exercises along with 2 education session in a group format.",[18],"Other: Pharmacy-Physiotherapy Intervention",[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":12},"Pharmacy-Physiotherapy Intervention","Pharmacists will provide comprehensive 1:1 patient care, including a complete patient assessment and medication review, provide specific drug therapy recommendation(s) using shared decision making (SDM), and provide patient education, including further written materials.\n\nParticipants will be offered either individual or group physiotherapy sessions at the a private clinic.",[14],[25,28,30],{"name":26,"affiliation":5,"role":27},"Ross Tsuyuki","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":5,"role":27},"Jill Hall",{"name":31,"affiliation":5,"role":27},"Allyson Jones",[33,37],{"name":31,"role":34,"phone":35,"phoneExt":12,"email":36},"CONTACT","780-492-2020","cajones@ualberta.ca",{"name":38,"role":34,"phone":12,"phoneExt":12,"email":39},"Jordyn Burgar","burgar@ucalgary.ca",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":12,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Mint Health & Drugs Sherwood Park","RECRUITING","Sherwood Park","Alberta","Canada","CA",{"type":49,"coordinates":50},"Point",[51,52],-113.3187,53.51684,{"lat":52,"lon":51},[55],{"name":38,"role":34,"phone":56,"phoneExt":12,"email":57},"780-989-1282","burgar@ualberta.ca",{"type":59,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100568432","pharmacist-physiotherapist-collaborative-management-for-early-knee-osteoarthritis-100568432",false,"NCT06681142","Pharmacist-physiotherapist Collaborative Management for Early Knee Osteoarthritis","PACE-OA","Inclusion Criteria:\n\n* regularly experiencing pain, aching, or stiffness in and\u002For around the knee for at least 1 month\n* complete the screening PhIT-OA questionnaire\n\nExclusion Criteria:\n\n* Prior total knee replacement or on the waitlist to have your knee replaced\n* Knee surgery within the previous 4 months\n* History of acute injury to knee within previous 6 months\n* Unable to speak and read English\n* Unwilling or unable to visit a physiotherapist at a community physiotherapy clinic (specifically the dates and times of the partnering physiotherapy clinic)\n* Previous physician-diagnosed inflammatory arthritis (including this list): Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, Lupus, Gout\n* Physician diagnosed fibromyalgia\n* A sudden, severely painful, hot, swollen joint at any time in the past\n* History of the following medications: csDMARD or bDMARD or tsDMARD, Immunosuppressive, Allopurinol or febuxostat, Colchicine\n* Received a knee joint injection in the past 3 months or have one scheduled in the next 3 months\n* Has completed the GLA:D Hip and Knee program at all in the past","ALL","50 Years",{"count":70,"type":71},125,"ESTIMATED","INTERVENTIONAL",[74],"NA","Osteoarthritis (OA) is a slowly progressive chronic condition that is associated with aging and is characterized as joint pain. Individuals with early-stage OA usually do not seek medical attention. If and when they do, patients more often present to a pharmacy for over-the-counter medications.\n\nThe investigators want to leverage community pharmacists' accessibility and scope of practice to best support patients with early knee OA. Given there are no disease-modifying treatments for OA, treatment guidelines center on patient education, self-management, and exercise, with medications playing a supporting role. Self-management is an effective strategy that provides a solid foundation for managing this progressive chronic condition and health care professionals like physiotherapists and pharmacists can help with the development and application of these skills.",[77,78,79],"Osteoarthritis (OA) of the Knee","Physiotherapy","Pharmacy","2026-06-23",{"date":82,"type":83},"2026-06-26","ACTUAL",{"date":85,"type":83},"2025-08-13",{"date":87,"type":71},"2027-09",{"name":5,"class":6},1]