[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587526":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":60,"collaborators":63,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":75,"sex":81,"minAge":82,"maxAge":19,"enrollmentInfo":83,"targetDuration":19,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":95,"overallStatus":50,"whyStopped":19,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Pharmacogenetic Testing","EXPERIMENTAL","Pharmacogenetic testing panel (CYP2C19, CYP2D6, CYP2B6, CYP3A4, CYP3A5, CYP2C9, CYP4F2, DPYD, HLA-A, HLA-B, NUDT15, SLCO1B1, TPMT, VKORC1, 2C Cluster, UGT1A1)",[13],"Diagnostic Test: Pharmacogenetic Testing",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DIAGNOSTIC_TEST","Participants will donate a 1ml (one-fifth of a teaspoon) sample of saliva. DNA extracted from the saliva sample will be used for genotyping. Genotyping results will be translated into an interpretative clinical report using evidence-based software (Sequence2Script) and delivered to the treating physician for use in their clinical decision-making. The report will contain genotyping results, predicted phenotype, and evidence-based drug selection and dosing recommendations relevant to the patient's current and future care.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Abdullah Al Maruf, PhD, M.Pharm., B.Pharm","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Abdullah Al Maruf, BPharm, MPharm, PhD","CONTACT","204-318-2575","abdullah.maruf@umanitoba.ca",[31,48],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Shared Health Facilities","NOT_YET_RECRUITING","Winnipeg","Manitoba","R3C 3H8","Canada","CA",{"type":40,"coordinates":41},"Point",[42,43],-97.14704,49.8844,{"lat":43,"lon":42},[46],{"name":47,"role":27,"phone":28,"phoneExt":19,"email":29},"Abdullah Al Maruf, PhD, M.Pharm, B.Pharm",{"facility":49,"status":50,"city":34,"state":35,"zip":51,"country":37,"countryCode":38,"cosmosGeoPoint":52,"geoPoint":54,"contacts":55},"University of Manitoba College of Pharmacy","RECRUITING","R3E 0T5",{"type":40,"coordinates":53},[42,43],{"lat":43,"lon":42},[56,57],{"name":47,"role":27,"phone":28,"phoneExt":19,"email":29},{"name":58,"role":27,"phone":19,"phoneExt":19,"email":59},"Mahin Hasan, MSc, BSc","hasanm33@myumanitoba.ca",{"type":23,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Abdullah Al Maruf","Assistant Professor",[64,66,69,71],{"name":65,"class":6},"University of Calgary",{"name":67,"class":68},"Shared Health Manitoba","UNKNOWN",{"name":70,"class":6},"Winnipeg Regional Health Authority",{"name":72,"class":6},"Health Sciences Centre, Winnipeg, Manitoba","100587526","pharmacogenomics-supported-psychotropic-prescribing-trial-100587526",false,"NCT06929533","Pharmacogenomics-Supported Psychotropic Prescribing Trial","Pharmacogenomics-Supported Psychotropic Prescribing Trial (PGx-SUPPORT): A Pilot Implementation Study in Manitoba","PGx-SUPPORT","Inclusion Criteria:\n\n* Aged 18 years or older\n* The initiation, change, dose adjustment, or augmentation of psychotropic medication(s) is indicated\n* The treating clinician thinks PGx testing can benefit and refers the patient to the study\n\nExclusion Criteria:\n\n* Unwillingness to donate saliva samples for genetic analysis\n* History of liver or bone marrow (hematopoietic cell) transplantation\n* PGx testing results are already available\n* No personal health identification number (PHIN) is available","ALL","18 Years",{"count":84,"type":85},200,"ESTIMATED","INTERVENTIONAL",[88],"NA","Investigate the feasibility and utility of implementing pharmacogenetic testing for adults (aged 18 and older) seeking care for mental illness in Manitoba.",[91,92,93,94],"Mental Disorder","Pharmacogenetics","Adverse Drug Reaction (ADR)","Effectiveness",[96,97,98,92,99,100,101,102,103,104],"Adult","Mental Health","Psychiatry","Depression","Anxiety","OCD","Psychosis","Bipolar Disorder","mental illness","2025-09-01",{"date":107,"type":108},"2025-09-08","ACTUAL",{"date":110,"type":108},"2025-07-01",{"date":112,"type":85},"2030-12-31",{"name":5,"class":6},2]