[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100331296":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":57,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Pediatric Patients on ECMO Support",null,[12,13,14,15],"Drug: Dexmedetomidine","Drug: Fentanyl","Drug: Midazolam","Drug: Morphine",[17,22,25,28],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DRUG","Dexmedetomidine","Administered for sedation management per hospital protocol",[9],{"type":18,"name":23,"description":20,"armGroupLabels":24,"otherNames":10},"Fentanyl",[9],{"type":18,"name":26,"description":20,"armGroupLabels":27,"otherNames":10},"Midazolam",[9],{"type":18,"name":29,"description":20,"armGroupLabels":30,"otherNames":10},"Morphine",[9],[32],{"name":33,"affiliation":5,"role":34},"Viviane Nasr, MD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":10,"email":39},"CONTACT","617-355-6225","viviane.nasr@childrens.harvard.edu",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-71.05977,42.35843,{"lat":52,"lon":51},[55,56],{"name":33,"role":37,"phone":10,"phoneExt":10,"email":10},{"name":33,"role":34,"phone":10,"phoneExt":10,"email":10},{"type":34,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Viviane Nasr","Cardiac Anesthesiologist","100331296","pharmacokinetics-of-sedatives-and-analgesics-during-extracorporeal-membrane-oxygenation-ecmo-support-100331296",false,"NCT03593408","Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support","Inclusion Criteria:\n\n* supported on ECMO\n* receiving one or a combination of the following drugs dexmedetomidine, fentanyl, midazolam or morphine as part of sedation management\n\nExclusion Criteria:\n\n-none","ALL","0 Days","17 Years",{"count":70,"type":71},20,"ESTIMATED","OBSERVATIONAL","This study will measure plasma concentrations of dexmedetomidine, fentanyl, morphine and midazolam in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to understand the pharmacokinetics of these drugs in this setting.",[75],"Drug Effect","2026-01-08",{"date":78,"type":79},"2026-01-09","ACTUAL",{"date":81,"type":79},"2019-02-08",{"date":83,"type":71},"2026-12-01",{"name":5,"class":6},1]