[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552888":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":39,"locations":26,"responsibleParty":49,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":26,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":77,"whyStopped":26,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":26},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MTA pulpotomy","ACTIVE_COMPARATOR","pulpotomy with MTA applied in the vital pulp therapy",[13],"Drug: MTA pulpotomy",{"label":15,"type":16,"description":17,"interventionNames":18},"3 Mixtatin pulpotomy","EXPERIMENTAL","pulpotomy with 3 mixtatin (triple antibiotic paste of (Metronidazole, cefixime, and Ciprofloxacin mixed with simvastatin ) applied in the vital pulp therapy",[19],"Drug: 3 mixtatin pulpotomy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","3 mixtatin pulpotomy","pulp treatment with applying 3mixture of antibiotic (Metronidazole, cefixime, and Ciprofloxacin) along with simvastatin",[15],null,{"type":22,"name":9,"description":28,"armGroupLabels":29,"otherNames":26},"pulp treatment with applying MTA",[9],[31,35],{"name":32,"affiliation":33,"role":34},"Randa y Abd Al Gawad, professor","Professor of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University","STUDY_DIRECTOR",{"name":36,"affiliation":37,"role":38},"Yasmin M Yousry, Associate professor","Assistant Professor of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University","STUDY_CHAIR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":26,"email":44},"Sally A kotb, PHD researcher","CONTACT","00201001656502","sallyqutb9933@gmail.com",{"name":46,"role":42,"phone":47,"phoneExt":26,"email":48},"Eslam M Mahdy","00201143683135","eslam.mahdy@dentistry.cu.edu.eg",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Sally Ahmed Kotb","doctor","100552888","phase-1-3mixtatin-and-mta-vital-pulpotomy-in-primary-molars-100552888",false,"NCT06478940","3Mixtatin and MTA Vital Pulpotomy in Primary Molars","Clinical and Radiographic Evaluation of 3Mixtatin Versus MTA Used as Pulpotomy Agents in Vital Primary Molars: A Randomized Clinical Trial","Inclusion Criteria:\n\n* • Children 4-8 years old\n\n  * Vital deeply carious primary molars.\n  * No history of spontaneous pain, pathologic mobility, draining sinus tract, redness or swelling of the vestibule.\n  * Normal gingival and periodontal condition, with no sensitivity to vestibular palpation, and no pain on percussion test.\n  * Patient and parent showing cooperation and compliance.\n\nExclusion Criteria:\n\n* • Uncooperative children to avoid time waste and attrition bias.\n\n  * Unrestorable molars\n  * Sign of radiolucency in periapical or furcation area\n  * Widening of PDL space or loss of lamina dura continuity\n  * Evidence of internal\u002Fexternal pathologic root resorption\n  * During operative procedure, when hemorrhage control is not achievable after pulpotomy.\n  * Children with systemic disease as some systemic diseases may have effect on the outcome.\n  * Unable to attend follow-up visits to avoid attrition bias by decreasing number of drop off cases.\n  * Refusal of participation as the parent of child has the authority of participation.",true,"ALL","4 Years","8 Years",{"count":65,"type":66},50,"ESTIMATED","INTERVENTIONAL",[69],"PHASE1","The aim of the study is to evaluate clinical and radiographic success of using 3Mixtain versus mineral trioxide aggregate in pulpotomy of deeply carious Primary molars.",[72,73],"Pulp Disease, Dental","Deciduous Teeth",[75,76],"pulpotomy - vital pulp therapy","primary molars- baby teeth","NOT_YET_RECRUITING","2024-06-23",{"date":80,"type":81},"2024-06-27","ACTUAL",{"date":83,"type":66},"2024-08-01",{"date":85,"type":66},"2025-09-01",{"name":5,"class":6}]