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Study participants on therapeutic doses of anticoagulation medication must have INR and\u002For aPTT ≤ the upper limit of the therapeutic range for intended use\n* Have recovered (ie, improvement to Grade 1 or better) from all acute toxicities from previous therapy, excluding alopecia and vitiligo.\n\nBHV-1510 in Combination with specific inclusion criteria:\n\n* histologically or cytologically documented advanced (locally, recurrent, inoperable, cannot betreated with curative intent) or metastatic cancer including Endometrial Carcinoma that is confirmed as proficient mismatch repair (pMMR)\n* received ≤ 2 prior lines of systemic anti-cancer therapy and at most one prior anti-programmed cell death protein 1 (PD-1) (programmed death-ligand 1 \\[PD-L1\\]) therapy for advanced\u002F metastatic disease.\n\nKey Exclusion Criteria:\n\n* Women who are pregnant or lactating.\n* Clinically significant intercurrent disease.\n* Has symptomatic brain metastases or has had any radiation or surgery for brain metastases within 4 weeks of C1D1.\n* Has clinically significant corneal disease.\n* Requires supplemental oxygen for daily activities.\n* Previous treatment with a Trop-2-targeted therapy, including Trop-2 ADCs.\n* Has a medical history of interstitial lung disease (eg, noninfectious interstitial pneumonia requiring steroid treatment, pneumonitis, pulmonary fibrosis, or severe radiation pneumonitis) or current interstitial lung disease or are suspected to have any of these diseases based on imaging at Screening.\n* Any standard cancer therapy (eg, chemotherapy, hormonal therapy, radiotherapy, immunotherapy, biologic therapy treatment) or experimental therapy within 3 weeks or 5 half-lives, whichever is shorter, prior to C1D1. 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