[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100392410":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":55,"centralContacts":60,"locations":65,"responsibleParty":1262,"collaborators":50,"id":1264,"slug":1265,"hasResults":1266,"nctId":1267,"briefTitle":1268,"officialTitle":1269,"acronym":50,"eligibilityCriteria":1270,"healthyVolunteers":1266,"sex":1271,"minAge":1272,"maxAge":50,"enrollmentInfo":1273,"targetDuration":50,"studyType":1276,"phases":1277,"briefSummary":1279,"conditions":1280,"keywords":1293,"overallStatus":68,"whyStopped":50,"lastUpdateSubmitDate":1310,"lastUpdatePostDateStruct":1311,"startDateStruct":1314,"completionDateStruct":1316,"leadSponsor":1318,"locationsCount":1320},{"fullName":5,"class":6},"Seagen Inc.","INDUSTRY",[8,14,17,24,28],{"label":9,"type":10,"description":11,"interventionNames":12},"Part A: Dose escalation","EXPERIMENTAL","sigvotatug vedotin monotherapy",[13],"Drug: sigvotatug vedotin",{"label":15,"type":10,"description":11,"interventionNames":16},"Part B: Dose expansion",[13],{"label":18,"type":10,"description":19,"interventionNames":20},"Part C: sigvotatug vedotin combination therapy in NSCLC, HNSCC, ESCC","sigvotatug vedotin + pembrolizumab +\u002F- (carboplatin or cisplatin)",[13,21,22,23],"Drug: pembrolizumab","Drug: cisplatin","Drug: carboplatin",{"label":25,"type":10,"description":26,"interventionNames":27},"Part D: sigvotatug vedotin combination therapy in 1L NSCLC","sigvotatug vedotin + pembrolizumab +\u002F- (carboplatin)",[13,21,23],{"label":29,"type":10,"description":19,"interventionNames":30},"Part D: sigvotatug vedotin combination therapy in 1L HNSCC",[13,21,22,23],[32,40,46,51],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"DRUG","sigvotatug vedotin","Administered into the vein (IV; intravenously)",[9,15,18,29,25],[38,39],"SGN-B6A","PF-08046047",{"type":33,"name":41,"description":42,"armGroupLabels":43,"otherNames":44},"pembrolizumab","200mg every 3 weeks or 400mg every 6 weeks, given by IV",[18,29,25],[45],"Keytruda",{"type":33,"name":47,"description":48,"armGroupLabels":49,"otherNames":50},"cisplatin","75 mg\u002Fm2 every 3 weeks, given by IV",[18,29],null,{"type":33,"name":52,"description":53,"armGroupLabels":54,"otherNames":50},"carboplatin","AUC 5 mg\u002FmL per min every 3 weeks, given by IV",[18,29,25],[56],{"name":57,"affiliation":58,"role":59},"Pfizer CT.gov Call Center","Pfizer","STUDY_DIRECTOR",[61],{"name":57,"role":62,"phone":63,"phoneExt":50,"email":64},"CONTACT","1-800-718-1021","ClinicalTrials.gov_Inquiries@pfizer.com",[66,80,90,98,106,116,124,129,139,144,153,158,163,172,181,191,197,206,211,220,229,234,244,253,259,264,273,282,291,300,309,314,319,324,330,335,341,350,360,369,378,384,390,394,404,409,418,423,428,433,442,450,455,465,471,477,482,487,496,506,515,524,534,544,552,560,567,573,581,589,597,605,613,624,634,639,644,654,660,665,670,680,686,696,706,712,717,726,735,744,753,759,768,778,788,797,802,811,819,828,834,843,852,858,867,872,883,892,901,910,919,924,935,945,954,960,966,972,978,990,1000,1010,1015,1025,1032,1038,1043,1048,1053,1058,1063,1068,1073,1078,1082,1091,1096,1102,1108,1114,1119,1125,1130,1135,1144,1155,1164,1170,1182,1191,1197,1209,1215,1224,1229,1238,1244,1250,1256],{"facility":67,"status":68,"city":69,"state":70,"zip":71,"country":72,"countryCode":73,"cosmosGeoPoint":74,"geoPoint":79,"contacts":50},"Alaska Oncology and Hematology","RECRUITING","Anchorage","Alaska","99508","United States","US",{"type":75,"coordinates":76},"Point",[77,78],-149.90028,61.21806,{"lat":78,"lon":77},{"facility":81,"status":68,"city":82,"state":83,"zip":84,"country":72,"countryCode":73,"cosmosGeoPoint":85,"geoPoint":89,"contacts":50},"Highlands Oncology Group","Fayetteville","Arkansas","72703",{"type":75,"coordinates":86},[87,88],-94.15743,36.06258,{"lat":88,"lon":87},{"facility":81,"status":68,"city":91,"state":83,"zip":92,"country":72,"countryCode":73,"cosmosGeoPoint":93,"geoPoint":97,"contacts":50},"Rogers","72758",{"type":75,"coordinates":94},[95,96],-94.11854,36.33202,{"lat":96,"lon":95},{"facility":81,"status":68,"city":99,"state":83,"zip":100,"country":72,"countryCode":73,"cosmosGeoPoint":101,"geoPoint":105,"contacts":50},"Springdale","72762",{"type":75,"coordinates":102},[103,104],-94.12881,36.18674,{"lat":104,"lon":103},{"facility":107,"status":68,"city":108,"state":109,"zip":110,"country":72,"countryCode":73,"cosmosGeoPoint":111,"geoPoint":115,"contacts":50},"Providence Medical Foundation","Anaheim","California","92805",{"type":75,"coordinates":112},[113,114],-117.9145,33.83529,{"lat":114,"lon":113},{"facility":107,"status":68,"city":117,"state":109,"zip":118,"country":72,"countryCode":73,"cosmosGeoPoint":119,"geoPoint":123,"contacts":50},"Fullerton","92835",{"type":75,"coordinates":120},[121,122],-117.92534,33.87029,{"lat":122,"lon":121},{"facility":125,"status":68,"city":117,"state":109,"zip":118,"country":72,"countryCode":73,"cosmosGeoPoint":126,"geoPoint":128,"contacts":50},"Providence St. Jude Medical Center Virginia K Crosson and Infusion Center",{"type":75,"coordinates":127},[121,122],{"lat":122,"lon":121},{"facility":130,"status":131,"city":132,"state":109,"zip":133,"country":72,"countryCode":73,"cosmosGeoPoint":134,"geoPoint":138,"contacts":50},"Cancer and Blood Research Center, LLC","NOT_YET_RECRUITING","Los Alamitos","90720",{"type":75,"coordinates":135},[136,137],-118.07256,33.80307,{"lat":137,"lon":136},{"facility":140,"status":131,"city":132,"state":109,"zip":133,"country":72,"countryCode":73,"cosmosGeoPoint":141,"geoPoint":143,"contacts":50},"Cancer and Blood Specialty Clinic",{"type":75,"coordinates":142},[136,137],{"lat":137,"lon":136},{"facility":145,"status":68,"city":146,"state":109,"zip":147,"country":72,"countryCode":73,"cosmosGeoPoint":148,"geoPoint":152,"contacts":50},"Ronald Reagan UCLA Medical Center","Los Angeles","90095",{"type":75,"coordinates":149},[150,151],-118.24368,34.05223,{"lat":151,"lon":150},{"facility":154,"status":68,"city":146,"state":109,"zip":147,"country":72,"countryCode":73,"cosmosGeoPoint":155,"geoPoint":157,"contacts":50},"The Regents of the University of California",{"type":75,"coordinates":156},[150,151],{"lat":151,"lon":150},{"facility":159,"status":68,"city":146,"state":109,"zip":147,"country":72,"countryCode":73,"cosmosGeoPoint":160,"geoPoint":162,"contacts":50},"UCLA Department of Medicine-Hematology\u002FOncology",{"type":75,"coordinates":161},[150,151],{"lat":151,"lon":150},{"facility":164,"status":68,"city":165,"state":109,"zip":166,"country":72,"countryCode":73,"cosmosGeoPoint":167,"geoPoint":171,"contacts":50},"UCLA Department of Medicine - Hematology & Oncology","Santa Monica","90404",{"type":75,"coordinates":168},[169,170],-118.49138,34.01949,{"lat":170,"lon":169},{"facility":173,"status":131,"city":174,"state":109,"zip":175,"country":72,"countryCode":73,"cosmosGeoPoint":176,"geoPoint":180,"contacts":50},"Cancer AND Blood Specialty Clinic","Torrance","90505",{"type":75,"coordinates":177},[178,179],-118.34063,33.83585,{"lat":179,"lon":178},{"facility":182,"status":68,"city":183,"state":184,"zip":185,"country":72,"countryCode":73,"cosmosGeoPoint":186,"geoPoint":190,"contacts":50},"American Oncology Partners, PA. a Florida professional service corporation, d\u002Fb\u002Fa Vista Oncology","Fort Myers","Florida","33913",{"type":75,"coordinates":187},[188,189],-81.84059,26.62168,{"lat":189,"lon":188},{"facility":192,"status":68,"city":183,"state":184,"zip":193,"country":72,"countryCode":73,"cosmosGeoPoint":194,"geoPoint":196,"contacts":50},"Florida Cancer Specialists & Research Institute, LLC","33916",{"type":75,"coordinates":195},[188,189],{"lat":189,"lon":188},{"facility":198,"status":68,"city":199,"state":184,"zip":200,"country":72,"countryCode":73,"cosmosGeoPoint":201,"geoPoint":205,"contacts":50},"Memorial Cancer Institute","Hollywood","33021",{"type":75,"coordinates":202},[203,204],-80.14949,26.0112,{"lat":204,"lon":203},{"facility":207,"status":68,"city":199,"state":184,"zip":200,"country":72,"countryCode":73,"cosmosGeoPoint":208,"geoPoint":210,"contacts":50},"Memorial Healthcare System",{"type":75,"coordinates":209},[203,204],{"lat":204,"lon":203},{"facility":212,"status":68,"city":213,"state":184,"zip":214,"country":72,"countryCode":73,"cosmosGeoPoint":215,"geoPoint":219,"contacts":50},"Florida Cancer Specialists","Orlando","32827",{"type":75,"coordinates":216},[217,218],-81.37924,28.53834,{"lat":218,"lon":217},{"facility":221,"status":68,"city":222,"state":184,"zip":223,"country":72,"countryCode":73,"cosmosGeoPoint":224,"geoPoint":228,"contacts":50},"Memorial Cancer Institute at Memorial Hospital West","Pembroke Pines","33028",{"type":75,"coordinates":225},[226,227],-80.22394,26.00315,{"lat":227,"lon":226},{"facility":230,"status":68,"city":222,"state":184,"zip":223,"country":72,"countryCode":73,"cosmosGeoPoint":231,"geoPoint":233,"contacts":50},"Memorial Hospital West",{"type":75,"coordinates":232},[226,227],{"lat":227,"lon":226},{"facility":235,"status":68,"city":236,"state":237,"zip":238,"country":72,"countryCode":73,"cosmosGeoPoint":239,"geoPoint":243,"contacts":50},"Ingalls Family Care Center","Calumet City","Illinois","60409",{"type":75,"coordinates":240},[241,242],-87.52949,41.61559,{"lat":242,"lon":241},{"facility":245,"status":68,"city":246,"state":237,"zip":247,"country":72,"countryCode":73,"cosmosGeoPoint":248,"geoPoint":252,"contacts":50},"UChicago Medicine - River East","Chicago","60611",{"type":75,"coordinates":249},[250,251],-87.65005,41.85003,{"lat":251,"lon":250},{"facility":254,"status":68,"city":246,"state":237,"zip":255,"country":72,"countryCode":73,"cosmosGeoPoint":256,"geoPoint":258,"contacts":50},"The University Of Chicago","60637",{"type":75,"coordinates":257},[250,251],{"lat":251,"lon":250},{"facility":260,"status":68,"city":246,"state":237,"zip":255,"country":72,"countryCode":73,"cosmosGeoPoint":261,"geoPoint":263,"contacts":50},"University of Chicago Medical Center",{"type":75,"coordinates":262},[250,251],{"lat":251,"lon":250},{"facility":265,"status":68,"city":266,"state":237,"zip":267,"country":72,"countryCode":73,"cosmosGeoPoint":268,"geoPoint":272,"contacts":50},"UChicago Medicine at Ingalls - Flossmoor","Flossmoor","60422",{"type":75,"coordinates":269},[270,271],-87.68477,41.54281,{"lat":271,"lon":270},{"facility":274,"status":68,"city":275,"state":237,"zip":276,"country":72,"countryCode":73,"cosmosGeoPoint":277,"geoPoint":281,"contacts":50},"UChicago Medicine Ingalls Memorial","Harvey","60426",{"type":75,"coordinates":278},[279,280],-87.64671,41.61003,{"lat":280,"lon":279},{"facility":283,"status":68,"city":284,"state":237,"zip":285,"country":72,"countryCode":73,"cosmosGeoPoint":286,"geoPoint":290,"contacts":50},"University of Chicago Comprehensive Cancer Center at Silver Cross Hospital","New Lenox","60451",{"type":75,"coordinates":287},[288,289],-87.96561,41.51198,{"lat":289,"lon":288},{"facility":292,"status":68,"city":293,"state":237,"zip":294,"country":72,"countryCode":73,"cosmosGeoPoint":295,"geoPoint":299,"contacts":50},"The University of Chicago Medicine Center for Advanced Care Orland Park","Orland Park","60462",{"type":75,"coordinates":296},[297,298],-87.85394,41.63031,{"lat":298,"lon":297},{"facility":301,"status":68,"city":302,"state":237,"zip":303,"country":72,"countryCode":73,"cosmosGeoPoint":304,"geoPoint":308,"contacts":50},"Southern Illinois University - Simmons Cancer Institute","Springfield","62702",{"type":75,"coordinates":305},[306,307],-89.64371,39.80172,{"lat":307,"lon":306},{"facility":310,"status":68,"city":302,"state":237,"zip":303,"country":72,"countryCode":73,"cosmosGeoPoint":311,"geoPoint":313,"contacts":50},"Springfield Clinic Radiology - 800 Building",{"type":75,"coordinates":312},[306,307],{"lat":307,"lon":306},{"facility":315,"status":68,"city":302,"state":237,"zip":303,"country":72,"countryCode":73,"cosmosGeoPoint":316,"geoPoint":318,"contacts":50},"Springfield Clinic Urgent Care Plus",{"type":75,"coordinates":317},[306,307],{"lat":307,"lon":306},{"facility":320,"status":68,"city":302,"state":237,"zip":303,"country":72,"countryCode":73,"cosmosGeoPoint":321,"geoPoint":323,"contacts":50},"Springfield Clinic",{"type":75,"coordinates":322},[306,307],{"lat":307,"lon":306},{"facility":325,"status":68,"city":302,"state":237,"zip":326,"country":72,"countryCode":73,"cosmosGeoPoint":327,"geoPoint":329,"contacts":50},"Springfield Clinic Main Campus","62703",{"type":75,"coordinates":328},[306,307],{"lat":307,"lon":306},{"facility":331,"status":68,"city":302,"state":237,"zip":326,"country":72,"countryCode":73,"cosmosGeoPoint":332,"geoPoint":334,"contacts":50},"Springfield Clinic Radiology - Main Campus",{"type":75,"coordinates":333},[306,307],{"lat":307,"lon":306},{"facility":336,"status":68,"city":302,"state":237,"zip":337,"country":72,"countryCode":73,"cosmosGeoPoint":338,"geoPoint":340,"contacts":50},"Springfield Memorial Hospital","62781",{"type":75,"coordinates":339},[306,307],{"lat":307,"lon":306},{"facility":342,"status":68,"city":343,"state":237,"zip":344,"country":72,"countryCode":73,"cosmosGeoPoint":345,"geoPoint":349,"contacts":50},"UChicago Medicine at Ingalls - Tinley Park","Tinley Park","60477",{"type":75,"coordinates":346},[347,348],-87.78449,41.57337,{"lat":348,"lon":347},{"facility":351,"status":68,"city":352,"state":353,"zip":354,"country":72,"countryCode":73,"cosmosGeoPoint":355,"geoPoint":359,"contacts":50},"UChicago Medicine - Northwest Indiana","Crown Point","Indiana","46307",{"type":75,"coordinates":356},[357,358],-87.36531,41.41698,{"lat":358,"lon":357},{"facility":361,"status":68,"city":362,"state":353,"zip":363,"country":72,"countryCode":73,"cosmosGeoPoint":364,"geoPoint":368,"contacts":50},"Fort Wayne Medical Oncology and Hematology, Inc","Fort Wayne","46804",{"type":75,"coordinates":365},[366,367],-85.12886,41.1306,{"lat":367,"lon":366},{"facility":370,"status":68,"city":371,"state":353,"zip":372,"country":72,"countryCode":73,"cosmosGeoPoint":373,"geoPoint":377,"contacts":50},"Community Health Network, Inc","Indianapolis","46219",{"type":75,"coordinates":374},[375,376],-86.15804,39.76838,{"lat":376,"lon":375},{"facility":379,"status":68,"city":371,"state":353,"zip":380,"country":72,"countryCode":73,"cosmosGeoPoint":381,"geoPoint":383,"contacts":50},"Community Health Network, Inc.","46227",{"type":75,"coordinates":382},[375,376],{"lat":376,"lon":375},{"facility":385,"status":68,"city":371,"state":353,"zip":386,"country":72,"countryCode":73,"cosmosGeoPoint":387,"geoPoint":389,"contacts":50},"Community Health Network Investigational Drug Services","46250",{"type":75,"coordinates":388},[375,376],{"lat":376,"lon":375},{"facility":379,"status":68,"city":371,"state":353,"zip":386,"country":72,"countryCode":73,"cosmosGeoPoint":391,"geoPoint":393,"contacts":50},{"type":75,"coordinates":392},[375,376],{"lat":376,"lon":375},{"facility":395,"status":68,"city":396,"state":397,"zip":398,"country":72,"countryCode":73,"cosmosGeoPoint":399,"geoPoint":403,"contacts":50},"The University of Kansas Cancer Center, Investigational Drug Services","Fairway","Kansas","66205",{"type":75,"coordinates":400},[401,402],-94.6319,39.02223,{"lat":402,"lon":401},{"facility":405,"status":68,"city":396,"state":397,"zip":398,"country":72,"countryCode":73,"cosmosGeoPoint":406,"geoPoint":408,"contacts":50},"The University of Kansas Clinical Research Center",{"type":75,"coordinates":407},[401,402],{"lat":402,"lon":401},{"facility":410,"status":68,"city":411,"state":397,"zip":412,"country":72,"countryCode":73,"cosmosGeoPoint":413,"geoPoint":417,"contacts":50},"The University of Kansas Hospital","Kansas City","66160",{"type":75,"coordinates":414},[415,416],-94.62746,39.11417,{"lat":416,"lon":415},{"facility":419,"status":68,"city":411,"state":397,"zip":412,"country":72,"countryCode":73,"cosmosGeoPoint":420,"geoPoint":422,"contacts":50},"The University of Kansas Medical Center Medical Office Building",{"type":75,"coordinates":421},[415,416],{"lat":416,"lon":415},{"facility":424,"status":68,"city":411,"state":397,"zip":412,"country":72,"countryCode":73,"cosmosGeoPoint":425,"geoPoint":427,"contacts":50},"University of Kansas Hospital Cambridge North Tower A",{"type":75,"coordinates":426},[415,416],{"lat":416,"lon":415},{"facility":429,"status":68,"city":411,"state":397,"zip":412,"country":72,"countryCode":73,"cosmosGeoPoint":430,"geoPoint":432,"contacts":50},"University of Kansas Medical Center Research Institute",{"type":75,"coordinates":431},[415,416],{"lat":416,"lon":415},{"facility":434,"status":68,"city":435,"state":397,"zip":436,"country":72,"countryCode":73,"cosmosGeoPoint":437,"geoPoint":441,"contacts":50},"The University of Kansas Cancer Center - Indian Creek Campus","Overland Park","66211",{"type":75,"coordinates":438},[439,440],-94.67079,38.98223,{"lat":440,"lon":439},{"facility":443,"status":68,"city":444,"state":397,"zip":398,"country":72,"countryCode":73,"cosmosGeoPoint":445,"geoPoint":449,"contacts":50},"The University of Kansas Cancer Center - Westwood","Westwood",{"type":75,"coordinates":446},[447,448],-94.6169,39.04056,{"lat":448,"lon":447},{"facility":451,"status":68,"city":444,"state":397,"zip":398,"country":72,"countryCode":73,"cosmosGeoPoint":452,"geoPoint":454,"contacts":50},"University of Kansas Cancer Center",{"type":75,"coordinates":453},[447,448],{"lat":448,"lon":447},{"facility":456,"status":68,"city":457,"state":458,"zip":459,"country":72,"countryCode":73,"cosmosGeoPoint":460,"geoPoint":464,"contacts":50},"Massachusetts General Hospital","Boston","Massachusetts","02114",{"type":75,"coordinates":461},[462,463],-71.05977,42.35843,{"lat":463,"lon":462},{"facility":466,"status":68,"city":457,"state":458,"zip":467,"country":72,"countryCode":73,"cosmosGeoPoint":468,"geoPoint":470,"contacts":50},"Brigham & Women's Hospital","02115",{"type":75,"coordinates":469},[462,463],{"lat":463,"lon":462},{"facility":472,"status":68,"city":457,"state":458,"zip":473,"country":72,"countryCode":73,"cosmosGeoPoint":474,"geoPoint":476,"contacts":50},"Beth Israel Deaconess Medical Center,East Campus Research Pharmacy","02215",{"type":75,"coordinates":475},[462,463],{"lat":463,"lon":462},{"facility":478,"status":68,"city":457,"state":458,"zip":473,"country":72,"countryCode":73,"cosmosGeoPoint":479,"geoPoint":481,"contacts":50},"Beth Israel Deaconess Medical Center",{"type":75,"coordinates":480},[462,463],{"lat":463,"lon":462},{"facility":483,"status":68,"city":457,"state":458,"zip":473,"country":72,"countryCode":73,"cosmosGeoPoint":484,"geoPoint":486,"contacts":50},"Dana Farber Cancer Institute",{"type":75,"coordinates":485},[462,463],{"lat":463,"lon":462},{"facility":488,"status":68,"city":489,"state":458,"zip":490,"country":72,"countryCode":73,"cosmosGeoPoint":491,"geoPoint":495,"contacts":50},"Dana-Farber Cancer Institute - Chestnut Hill","Newton","02467",{"type":75,"coordinates":492},[493,494],-71.20922,42.33704,{"lat":494,"lon":493},{"facility":497,"status":68,"city":498,"state":499,"zip":500,"country":72,"countryCode":73,"cosmosGeoPoint":501,"geoPoint":505,"contacts":50},"Allina Health Cancer Institute - Mercy Hospital","Coon Rapids","Minnesota","55433",{"type":75,"coordinates":502},[503,504],-93.28773,45.11997,{"lat":504,"lon":503},{"facility":507,"status":68,"city":508,"state":499,"zip":509,"country":72,"countryCode":73,"cosmosGeoPoint":510,"geoPoint":514,"contacts":50},"Allina Health Cancer Institute - Abbott Northwestern Hospital","Minneapolis","55407",{"type":75,"coordinates":511},[512,513],-93.26384,44.97997,{"lat":513,"lon":512},{"facility":516,"status":68,"city":517,"state":499,"zip":518,"country":72,"countryCode":73,"cosmosGeoPoint":519,"geoPoint":523,"contacts":50},"Allina Health Cancer Institute","Saint Paul","55102",{"type":75,"coordinates":520},[521,522],-93.09327,44.94441,{"lat":522,"lon":521},{"facility":525,"status":68,"city":526,"state":527,"zip":528,"country":72,"countryCode":73,"cosmosGeoPoint":529,"geoPoint":533,"contacts":50},"Comprehensive Cancer Centers of Nevada","Las Vegas","Nevada","89169",{"type":75,"coordinates":530},[531,532],-115.13722,36.17497,{"lat":532,"lon":531},{"facility":535,"status":68,"city":536,"state":537,"zip":538,"country":72,"countryCode":73,"cosmosGeoPoint":539,"geoPoint":543,"contacts":50},"North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists","Babylon","New York","11702",{"type":75,"coordinates":540},[541,542],-73.32568,40.69566,{"lat":542,"lon":541},{"facility":535,"status":68,"city":545,"state":537,"zip":546,"country":72,"countryCode":73,"cosmosGeoPoint":547,"geoPoint":551,"contacts":50},"Brooklyn","11210",{"type":75,"coordinates":548},[549,550],-73.94958,40.6501,{"lat":550,"lon":549},{"facility":535,"status":68,"city":553,"state":537,"zip":554,"country":72,"countryCode":73,"cosmosGeoPoint":555,"geoPoint":559,"contacts":50},"New Hyde Park","11042",{"type":75,"coordinates":556},[557,558],-73.68791,40.7351,{"lat":558,"lon":557},{"facility":535,"status":68,"city":537,"state":537,"zip":561,"country":72,"countryCode":73,"cosmosGeoPoint":562,"geoPoint":566,"contacts":50},"10028",{"type":75,"coordinates":563},[564,565],-74.00597,40.71427,{"lat":565,"lon":564},{"facility":568,"status":68,"city":537,"state":537,"zip":569,"country":72,"countryCode":73,"cosmosGeoPoint":570,"geoPoint":572,"contacts":50},"Columbia University Irving Medical Center","10032",{"type":75,"coordinates":571},[564,565],{"lat":565,"lon":564},{"facility":535,"status":68,"city":574,"state":537,"zip":575,"country":72,"countryCode":73,"cosmosGeoPoint":576,"geoPoint":580,"contacts":50},"Patchogue","11772",{"type":75,"coordinates":577},[578,579],-73.01511,40.76565,{"lat":579,"lon":578},{"facility":535,"status":68,"city":582,"state":537,"zip":583,"country":72,"countryCode":73,"cosmosGeoPoint":584,"geoPoint":588,"contacts":50},"Port Jefferson Station","11776",{"type":75,"coordinates":585},[586,587],-73.04733,40.92538,{"lat":587,"lon":586},{"facility":535,"status":68,"city":590,"state":537,"zip":591,"country":72,"countryCode":73,"cosmosGeoPoint":592,"geoPoint":596,"contacts":50},"Riverhead","11901",{"type":75,"coordinates":593},[594,595],-72.66204,40.91704,{"lat":595,"lon":594},{"facility":535,"status":68,"city":598,"state":537,"zip":599,"country":72,"countryCode":73,"cosmosGeoPoint":600,"geoPoint":604,"contacts":50},"Shirley","11967",{"type":75,"coordinates":601},[602,603],-72.8676,40.80149,{"lat":603,"lon":602},{"facility":535,"status":68,"city":606,"state":537,"zip":607,"country":72,"countryCode":73,"cosmosGeoPoint":608,"geoPoint":612,"contacts":50},"The Bronx","10469",{"type":75,"coordinates":609},[610,611],-73.86641,40.84985,{"lat":611,"lon":610},{"facility":614,"status":615,"city":616,"state":617,"zip":618,"country":72,"countryCode":73,"cosmosGeoPoint":619,"geoPoint":623,"contacts":50},"University Hospitals Cleveland Medical Center","ACTIVE_NOT_RECRUITING","Cleveland","Ohio","44106",{"type":75,"coordinates":620},[621,622],-81.69541,41.4995,{"lat":622,"lon":621},{"facility":625,"status":68,"city":626,"state":627,"zip":628,"country":72,"countryCode":73,"cosmosGeoPoint":629,"geoPoint":633,"contacts":50},"OU Health University of Oklahoma Medical Center","Oklahoma City","Oklahoma","73104",{"type":75,"coordinates":630},[631,632],-97.51643,35.46756,{"lat":632,"lon":631},{"facility":635,"status":68,"city":626,"state":627,"zip":628,"country":72,"countryCode":73,"cosmosGeoPoint":636,"geoPoint":638,"contacts":50},"Stephenson Cancer Center (chemo location)",{"type":75,"coordinates":637},[631,632],{"lat":632,"lon":631},{"facility":640,"status":68,"city":626,"state":627,"zip":628,"country":72,"countryCode":73,"cosmosGeoPoint":641,"geoPoint":643,"contacts":50},"University of Oklahoma Health Science Center",{"type":75,"coordinates":642},[631,632],{"lat":632,"lon":631},{"facility":645,"status":68,"city":646,"state":647,"zip":648,"country":72,"countryCode":73,"cosmosGeoPoint":649,"geoPoint":653,"contacts":50},"Providence Cancer Institute Franz Clinic","Portland","Oregon","97213",{"type":75,"coordinates":650},[651,652],-122.67621,45.52345,{"lat":652,"lon":651},{"facility":655,"status":68,"city":646,"state":647,"zip":656,"country":72,"countryCode":73,"cosmosGeoPoint":657,"geoPoint":659,"contacts":50},"Providence Oncology and Hematology Care Clinic - Westside","97225",{"type":75,"coordinates":658},[651,652],{"lat":652,"lon":651},{"facility":661,"status":68,"city":646,"state":647,"zip":656,"country":72,"countryCode":73,"cosmosGeoPoint":662,"geoPoint":664,"contacts":50},"Providence St. Vincent Medical Center- Investigational Drug Services",{"type":75,"coordinates":663},[651,652],{"lat":652,"lon":651},{"facility":666,"status":68,"city":646,"state":647,"zip":656,"country":72,"countryCode":73,"cosmosGeoPoint":667,"geoPoint":669,"contacts":50},"Providence St. Vincent Medical Center",{"type":75,"coordinates":668},[651,652],{"lat":652,"lon":651},{"facility":671,"status":68,"city":672,"state":673,"zip":674,"country":72,"countryCode":73,"cosmosGeoPoint":675,"geoPoint":679,"contacts":50},"Sanford Cancer Center","Sioux Falls","South Dakota","57104",{"type":75,"coordinates":676},[677,678],-96.72796,43.54369,{"lat":678,"lon":677},{"facility":681,"status":68,"city":672,"state":673,"zip":682,"country":72,"countryCode":73,"cosmosGeoPoint":683,"geoPoint":685,"contacts":50},"Sanford USD Medical Center","57105",{"type":75,"coordinates":684},[677,678],{"lat":678,"lon":677},{"facility":687,"status":68,"city":688,"state":689,"zip":690,"country":72,"countryCode":73,"cosmosGeoPoint":691,"geoPoint":695,"contacts":50},"US Oncology Research LLC","Nashville","Tennessee","37203",{"type":75,"coordinates":692},[693,694],-86.78444,36.16589,{"lat":694,"lon":693},{"facility":697,"status":68,"city":698,"state":699,"zip":700,"country":72,"countryCode":73,"cosmosGeoPoint":701,"geoPoint":705,"contacts":50},"Oncology Consultants, PA","Houston","Texas","77024",{"type":75,"coordinates":702},[703,704],-95.36327,29.76328,{"lat":704,"lon":703},{"facility":707,"status":68,"city":698,"state":699,"zip":708,"country":72,"countryCode":73,"cosmosGeoPoint":709,"geoPoint":711,"contacts":50},"Oncology Consultants, PA.","77030",{"type":75,"coordinates":710},[703,704],{"lat":704,"lon":703},{"facility":713,"status":68,"city":698,"state":699,"zip":708,"country":72,"countryCode":73,"cosmosGeoPoint":714,"geoPoint":716,"contacts":50},"The University of Texas M.D. Anderson Cancer Center",{"type":75,"coordinates":715},[703,704],{"lat":704,"lon":703},{"facility":718,"status":68,"city":719,"state":699,"zip":720,"country":72,"countryCode":73,"cosmosGeoPoint":721,"geoPoint":725,"contacts":50},"US Oncology Investigational Product Center (IPC)","Irving","75063",{"type":75,"coordinates":722},[723,724],-96.94889,32.81402,{"lat":724,"lon":723},{"facility":727,"status":131,"city":728,"state":699,"zip":729,"country":72,"countryCode":73,"cosmosGeoPoint":730,"geoPoint":734,"contacts":50},"Houston Medical Imaging","Pearland","77581",{"type":75,"coordinates":731},[732,733],-95.28605,29.56357,{"lat":733,"lon":732},{"facility":736,"status":615,"city":737,"state":699,"zip":738,"country":72,"countryCode":73,"cosmosGeoPoint":739,"geoPoint":743,"contacts":50},"South Texas Accelerated Research Therapeutics, LLC","San Antonio","78229",{"type":75,"coordinates":740},[741,742],-98.49363,29.42412,{"lat":742,"lon":741},{"facility":745,"status":68,"city":746,"state":699,"zip":747,"country":72,"countryCode":73,"cosmosGeoPoint":748,"geoPoint":752,"contacts":50},"UT Health East Texas HOPE Cancer Center","Tyler","75701",{"type":75,"coordinates":749},[750,751],-95.30106,32.35126,{"lat":751,"lon":750},{"facility":754,"status":68,"city":746,"state":699,"zip":755,"country":72,"countryCode":73,"cosmosGeoPoint":756,"geoPoint":758,"contacts":50},"UT Health East Texas Hope Cancer Center","75708",{"type":75,"coordinates":757},[750,751],{"lat":751,"lon":750},{"facility":760,"status":131,"city":761,"state":699,"zip":762,"country":72,"countryCode":73,"cosmosGeoPoint":763,"geoPoint":767,"contacts":50},"Tranquil Clinical Research","Webster","77598",{"type":75,"coordinates":764},[765,766],-95.11826,29.53773,{"lat":766,"lon":765},{"facility":769,"status":68,"city":770,"state":771,"zip":772,"country":72,"countryCode":73,"cosmosGeoPoint":773,"geoPoint":777,"contacts":50},"Virginia Cancer Specialists","Fairfax","Virginia","22031",{"type":75,"coordinates":774},[775,776],-77.30637,38.84622,{"lat":776,"lon":775},{"facility":779,"status":131,"city":780,"state":781,"zip":782,"country":72,"countryCode":73,"cosmosGeoPoint":783,"geoPoint":787,"contacts":50},"Northwest Medical Specialities. PLLC","Bonney Lake","Washington","98391",{"type":75,"coordinates":784},[785,786],-122.18651,47.17705,{"lat":786,"lon":785},{"facility":789,"status":68,"city":790,"state":781,"zip":791,"country":72,"countryCode":73,"cosmosGeoPoint":792,"geoPoint":796,"contacts":50},"Swedish Cancer Institute - Edmonds Campus","Edmonds","98026",{"type":75,"coordinates":793},[794,795],-122.37736,47.81065,{"lat":795,"lon":794},{"facility":798,"status":68,"city":790,"state":781,"zip":791,"country":72,"countryCode":73,"cosmosGeoPoint":799,"geoPoint":801,"contacts":50},"Swedish Cancer Institute Edmonds Campus",{"type":75,"coordinates":800},[794,795],{"lat":795,"lon":794},{"facility":803,"status":131,"city":804,"state":781,"zip":805,"country":72,"countryCode":73,"cosmosGeoPoint":806,"geoPoint":810,"contacts":50},"Northwest Medical Specialities.PLLC","Federal Way","98003",{"type":75,"coordinates":807},[808,809],-122.31262,47.32232,{"lat":809,"lon":808},{"facility":779,"status":131,"city":812,"state":781,"zip":813,"country":72,"countryCode":73,"cosmosGeoPoint":814,"geoPoint":818,"contacts":50},"Gig Harbor","98332",{"type":75,"coordinates":815},[816,817],-122.58013,47.32926,{"lat":817,"lon":816},{"facility":820,"status":68,"city":821,"state":781,"zip":822,"country":72,"countryCode":73,"cosmosGeoPoint":823,"geoPoint":827,"contacts":50},"American Oncology Network Vista Oncology Division-West office","Olympia","98502",{"type":75,"coordinates":824},[825,826],-122.90169,47.04491,{"lat":826,"lon":825},{"facility":829,"status":68,"city":821,"state":781,"zip":830,"country":72,"countryCode":73,"cosmosGeoPoint":831,"geoPoint":833,"contacts":50},"American Oncology Network Vista Oncology Division-East office","98506",{"type":75,"coordinates":832},[825,826],{"lat":826,"lon":825},{"facility":835,"status":131,"city":836,"state":781,"zip":837,"country":72,"countryCode":73,"cosmosGeoPoint":838,"geoPoint":842,"contacts":50},"Northwest Medical Specialties, PPLC","Puyallup","98373",{"type":75,"coordinates":839},[840,841],-122.2929,47.18538,{"lat":841,"lon":840},{"facility":844,"status":68,"city":845,"state":781,"zip":846,"country":72,"countryCode":73,"cosmosGeoPoint":847,"geoPoint":851,"contacts":50},"Swedish Cancer Institute","Seattle","98104",{"type":75,"coordinates":848},[849,850],-122.33207,47.60621,{"lat":850,"lon":849},{"facility":853,"status":68,"city":845,"state":781,"zip":854,"country":72,"countryCode":73,"cosmosGeoPoint":855,"geoPoint":857,"contacts":50},"Swedish Medical Center","98122",{"type":75,"coordinates":856},[849,850],{"lat":850,"lon":849},{"facility":859,"status":68,"city":860,"state":781,"zip":861,"country":72,"countryCode":73,"cosmosGeoPoint":862,"geoPoint":866,"contacts":50},"Exigent Research, LLC","Tacoma","98405",{"type":75,"coordinates":863},[864,865],-122.44429,47.25288,{"lat":865,"lon":864},{"facility":868,"status":131,"city":860,"state":781,"zip":861,"country":72,"countryCode":73,"cosmosGeoPoint":869,"geoPoint":871,"contacts":50},"Northwest Medical Specialities, PLLC",{"type":75,"coordinates":870},[864,865],{"lat":865,"lon":864},{"facility":873,"status":615,"city":874,"state":50,"zip":875,"country":876,"countryCode":877,"cosmosGeoPoint":878,"geoPoint":882,"contacts":50},"Center Hospitalier Universitaire d' Angers","Angers","49100","France","FR",{"type":75,"coordinates":879},[880,881],-0.55202,47.47156,{"lat":881,"lon":880},{"facility":884,"status":68,"city":885,"state":50,"zip":886,"country":876,"countryCode":877,"cosmosGeoPoint":887,"geoPoint":891,"contacts":50},"Centre de Lutte contre le Cancer (CLCC) - Centre Antoine Lacassagne","Nice","06189",{"type":75,"coordinates":888},[889,890],7.26608,43.70313,{"lat":890,"lon":889},{"facility":893,"status":68,"city":894,"state":50,"zip":895,"country":876,"countryCode":877,"cosmosGeoPoint":896,"geoPoint":900,"contacts":50},"Centre Hospitalier Universitaire de Poitiers","Poitiers","86021",{"type":75,"coordinates":897},[898,899],0.34348,46.58261,{"lat":899,"lon":898},{"facility":902,"status":68,"city":903,"state":50,"zip":904,"country":876,"countryCode":877,"cosmosGeoPoint":905,"geoPoint":909,"contacts":50},"Institut de Cancérologie de Lorraine","Vandœuvre-lès-Nancy","54519",{"type":75,"coordinates":906},[907,908],6.17114,48.66115,{"lat":908,"lon":907},{"facility":911,"status":68,"city":912,"state":50,"zip":913,"country":876,"countryCode":877,"cosmosGeoPoint":914,"geoPoint":918,"contacts":50},"Institut Gustave Roussy Department de Pharmacie Clinique(-1)","Villejuif","94805.",{"type":75,"coordinates":915},[916,917],2.35992,48.7939,{"lat":917,"lon":916},{"facility":920,"status":68,"city":912,"state":50,"zip":913,"country":876,"countryCode":877,"cosmosGeoPoint":921,"geoPoint":923,"contacts":50},"lnstitut Gustave Roussy, Departement d'lnnovation Therapeutique et d'Essais Precoces (DITEP)",{"type":75,"coordinates":922},[916,917],{"lat":917,"lon":916},{"facility":925,"status":68,"city":926,"state":927,"zip":928,"country":929,"countryCode":50,"cosmosGeoPoint":930,"geoPoint":934,"contacts":50},"National Cancer Center","Goyang-si","Gyeonggi-do","10408","South Korea",{"type":75,"coordinates":931},[932,933],126.835,37.65639,{"lat":933,"lon":932},{"facility":936,"status":68,"city":937,"state":938,"zip":939,"country":929,"countryCode":50,"cosmosGeoPoint":940,"geoPoint":944,"contacts":50},"Chungbuk National University Hospital","Cheongju-si","North Chungcheong","28644",{"type":75,"coordinates":941},[942,943],127.48972,36.63722,{"lat":943,"lon":942},{"facility":946,"status":68,"city":947,"state":50,"zip":948,"country":929,"countryCode":50,"cosmosGeoPoint":949,"geoPoint":953,"contacts":50},"Severance Hospital Yonsei University Health System","Seoul","03722",{"type":75,"coordinates":950},[951,952],126.9784,37.566,{"lat":952,"lon":951},{"facility":955,"status":131,"city":947,"state":50,"zip":956,"country":929,"countryCode":50,"cosmosGeoPoint":957,"geoPoint":959,"contacts":50},"Samsung Medical Center","06351",{"type":75,"coordinates":958},[951,952],{"lat":952,"lon":951},{"facility":961,"status":68,"city":947,"state":50,"zip":962,"country":929,"countryCode":50,"cosmosGeoPoint":963,"geoPoint":965,"contacts":50},"The Catholic University of Korea","06591",{"type":75,"coordinates":964},[951,952],{"lat":952,"lon":951},{"facility":967,"status":68,"city":947,"state":50,"zip":968,"country":929,"countryCode":50,"cosmosGeoPoint":969,"geoPoint":971,"contacts":50},"Seoul Metropolitan Government Seoul National University Boramae Medical Center","07061",{"type":75,"coordinates":970},[951,952],{"lat":952,"lon":951},{"facility":973,"status":68,"city":947,"state":50,"zip":974,"country":929,"countryCode":50,"cosmosGeoPoint":975,"geoPoint":977,"contacts":50},"Korea University Guro Hospital","08308",{"type":75,"coordinates":976},[951,952],{"lat":952,"lon":951},{"facility":979,"status":68,"city":980,"state":981,"zip":982,"country":983,"countryCode":984,"cosmosGeoPoint":985,"geoPoint":989,"contacts":50},"Farmacia Ensayos Hospital HM Universitario Sanchinarro","Madrid","Agrigento","28050","Spain","ES",{"type":75,"coordinates":986},[987,988],-3.70256,40.4165,{"lat":988,"lon":987},{"facility":991,"status":68,"city":992,"state":993,"zip":994,"country":983,"countryCode":984,"cosmosGeoPoint":995,"geoPoint":999,"contacts":50},"Elche General University Hospital","Elche","Alicante","03203",{"type":75,"coordinates":996},[997,998],-0.70107,38.26218,{"lat":998,"lon":997},{"facility":1001,"status":68,"city":1002,"state":1003,"zip":1004,"country":983,"countryCode":984,"cosmosGeoPoint":1005,"geoPoint":1009,"contacts":50},"Equipo de Farmacia Oncológica- Ensayos Clínicos Servicio de Farmacia Hospital Universitario Marqués","Santander","Cantabria","39008",{"type":75,"coordinates":1006},[1007,1008],-3.80493,43.46589,{"lat":1008,"lon":1007},{"facility":1011,"status":68,"city":1002,"state":1003,"zip":1004,"country":983,"countryCode":984,"cosmosGeoPoint":1012,"geoPoint":1014,"contacts":50},"Hospital Universitario Marques de Valdecilla",{"type":75,"coordinates":1013},[1007,1008],{"lat":1008,"lon":1007},{"facility":1016,"status":68,"city":1017,"state":1018,"zip":1019,"country":983,"countryCode":984,"cosmosGeoPoint":1020,"geoPoint":1024,"contacts":50},"Hospital HM Nou Delfos","Barcelona","Catalonia","08023",{"type":75,"coordinates":1021},[1022,1023],2.15899,41.38879,{"lat":1023,"lon":1022},{"facility":1026,"status":68,"city":1017,"state":1027,"zip":1028,"country":983,"countryCode":984,"cosmosGeoPoint":1029,"geoPoint":1031,"contacts":50},"Fundación Privada Instituto de Investigación Oncológica de Vall Hebron","Other","08035",{"type":75,"coordinates":1030},[1022,1023],{"lat":1023,"lon":1022},{"facility":1033,"status":68,"city":1017,"state":1034,"zip":1019,"country":983,"countryCode":984,"cosmosGeoPoint":1035,"geoPoint":1037,"contacts":50},"NEXT Oncology Barcelona - IOB - Hospital Quironsalud Barcelona","OTH",{"type":75,"coordinates":1036},[1022,1023],{"lat":1023,"lon":1022},{"facility":991,"status":68,"city":992,"state":1039,"zip":994,"country":983,"countryCode":984,"cosmosGeoPoint":1040,"geoPoint":1042,"contacts":50},"Valencia",{"type":75,"coordinates":1041},[997,998],{"lat":998,"lon":997},{"facility":1044,"status":68,"city":992,"state":1039,"zip":994,"country":983,"countryCode":984,"cosmosGeoPoint":1045,"geoPoint":1047,"contacts":50},"Hospital General Universitario de Elche",{"type":75,"coordinates":1046},[997,998],{"lat":998,"lon":997},{"facility":1049,"status":68,"city":1017,"state":50,"zip":1019,"country":983,"countryCode":984,"cosmosGeoPoint":1050,"geoPoint":1052,"contacts":50},"Farmacia Ensayos clínicos, Unidad START Barcelona",{"type":75,"coordinates":1051},[1022,1023],{"lat":1023,"lon":1022},{"facility":1054,"status":68,"city":1017,"state":50,"zip":1019,"country":983,"countryCode":984,"cosmosGeoPoint":1055,"geoPoint":1057,"contacts":50},"Hospital HM Nou Delfos - START Barcelona",{"type":75,"coordinates":1056},[1022,1023],{"lat":1023,"lon":1022},{"facility":1059,"status":68,"city":1017,"state":50,"zip":1019,"country":983,"countryCode":984,"cosmosGeoPoint":1060,"geoPoint":1062,"contacts":50},"Hospital Quiron Salud Barcelona",{"type":75,"coordinates":1061},[1022,1023],{"lat":1023,"lon":1022},{"facility":1064,"status":68,"city":1017,"state":50,"zip":1019,"country":983,"countryCode":984,"cosmosGeoPoint":1065,"geoPoint":1067,"contacts":50},"NEXT Oncology - IOB Hospital Quironsalud Barcelona",{"type":75,"coordinates":1066},[1022,1023],{"lat":1023,"lon":1022},{"facility":1069,"status":68,"city":1017,"state":50,"zip":1028,"country":983,"countryCode":984,"cosmosGeoPoint":1070,"geoPoint":1072,"contacts":50},"Area general-Planta Baixa | Unitat d'investigacio en terapia Molecular del Cancer \"la Caixa\"",{"type":75,"coordinates":1071},[1022,1023],{"lat":1023,"lon":1022},{"facility":1074,"status":68,"city":1017,"state":50,"zip":1028,"country":983,"countryCode":984,"cosmosGeoPoint":1075,"geoPoint":1077,"contacts":50},"Hospital Vall d'Hebron",{"type":75,"coordinates":1076},[1022,1023],{"lat":1023,"lon":1022},{"facility":991,"status":68,"city":992,"state":50,"zip":994,"country":983,"countryCode":984,"cosmosGeoPoint":1079,"geoPoint":1081,"contacts":50},{"type":75,"coordinates":1080},[997,998],{"lat":998,"lon":997},{"facility":1083,"status":68,"city":1084,"state":50,"zip":1085,"country":983,"countryCode":984,"cosmosGeoPoint":1086,"geoPoint":1090,"contacts":50},"Hospital Universitario De Jerez","Jerez de la Frontera","10407",{"type":75,"coordinates":1087},[1088,1089],-6.13606,36.68645,{"lat":1089,"lon":1088},{"facility":1092,"status":68,"city":1084,"state":50,"zip":1085,"country":983,"countryCode":984,"cosmosGeoPoint":1093,"geoPoint":1095,"contacts":50},"UGC Farmacia Ensayos clinicos - Hospital Universitario de Jerez",{"type":75,"coordinates":1094},[1088,1089],{"lat":1089,"lon":1088},{"facility":1097,"status":68,"city":1084,"state":50,"zip":1098,"country":983,"countryCode":984,"cosmosGeoPoint":1099,"geoPoint":1101,"contacts":50},"Hospital Universitario de Jerez","11407",{"type":75,"coordinates":1100},[1088,1089],{"lat":1089,"lon":1088},{"facility":1103,"status":68,"city":980,"state":50,"zip":1104,"country":983,"countryCode":984,"cosmosGeoPoint":1105,"geoPoint":1107,"contacts":50},"Fundación de Investigación Hm Hospitales, C.I.F. G-83643841","28015",{"type":75,"coordinates":1106},[987,988],{"lat":988,"lon":987},{"facility":1109,"status":68,"city":980,"state":50,"zip":1110,"country":983,"countryCode":984,"cosmosGeoPoint":1111,"geoPoint":1113,"contacts":50},"Hospital Universitario Ramon y Cajal","28034",{"type":75,"coordinates":1112},[987,988],{"lat":988,"lon":987},{"facility":1115,"status":68,"city":980,"state":50,"zip":1110,"country":983,"countryCode":984,"cosmosGeoPoint":1116,"geoPoint":1118,"contacts":50},"Servicio de Radiologia Hospital Universitario Ramon y Cajal",{"type":75,"coordinates":1117},[987,988],{"lat":988,"lon":987},{"facility":1120,"status":68,"city":980,"state":50,"zip":1121,"country":983,"countryCode":984,"cosmosGeoPoint":1122,"geoPoint":1124,"contacts":50},"Hospital Universitario 12 de Octubre","28041",{"type":75,"coordinates":1123},[987,988],{"lat":988,"lon":987},{"facility":1126,"status":68,"city":980,"state":50,"zip":1121,"country":983,"countryCode":984,"cosmosGeoPoint":1127,"geoPoint":1129,"contacts":50},"Hospital Universitario 12 Octubre",{"type":75,"coordinates":1128},[987,988],{"lat":988,"lon":987},{"facility":1131,"status":68,"city":980,"state":50,"zip":982,"country":983,"countryCode":984,"cosmosGeoPoint":1132,"geoPoint":1134,"contacts":50},"Hospital HM Sanchinarro, START-Madrid-CIOCC",{"type":75,"coordinates":1133},[987,988],{"lat":988,"lon":987},{"facility":1136,"status":68,"city":1137,"state":50,"zip":1138,"country":983,"countryCode":984,"cosmosGeoPoint":1139,"geoPoint":1143,"contacts":50},"Quironsalud Malaga","Málaga","129004",{"type":75,"coordinates":1140},[1141,1142],-4.42034,36.72016,{"lat":1142,"lon":1141},{"facility":1145,"status":68,"city":1146,"state":50,"zip":1147,"country":1148,"countryCode":1149,"cosmosGeoPoint":1150,"geoPoint":1154,"contacts":50},"Kantonsspital Graubunden","Chur","7000","Switzerland","CH",{"type":75,"coordinates":1151},[1152,1153],9.53287,46.84986,{"lat":1153,"lon":1152},{"facility":1156,"status":68,"city":1157,"state":50,"zip":1158,"country":1148,"countryCode":1149,"cosmosGeoPoint":1159,"geoPoint":1163,"contacts":50},"University Hospital Lausanne CHUV","Lausanne","1011",{"type":75,"coordinates":1160},[1161,1162],6.63282,46.516,{"lat":1162,"lon":1161},{"facility":1165,"status":68,"city":1157,"state":50,"zip":1166,"country":1148,"countryCode":1149,"cosmosGeoPoint":1167,"geoPoint":1169,"contacts":50},"CHUV - Service de pharmacie BH-04, Essais cliniques","CH-1011",{"type":75,"coordinates":1168},[1161,1162],{"lat":1162,"lon":1161},{"facility":1171,"status":68,"city":1172,"state":1173,"zip":1174,"country":1175,"countryCode":1176,"cosmosGeoPoint":1177,"geoPoint":1181,"contacts":50},"Kaohsiung Medical University Hospital","Kaohsiung City","R.o.c.","80756","Taiwan","TW",{"type":75,"coordinates":1178},[1179,1180],120.31333,22.61626,{"lat":1180,"lon":1179},{"facility":1183,"status":131,"city":1184,"state":50,"zip":1185,"country":1175,"countryCode":1176,"cosmosGeoPoint":1186,"geoPoint":1190,"contacts":50},"National Taiwan University Hospital","Taipei","100, R.O.C",{"type":75,"coordinates":1187},[1188,1189],121.52639,25.05306,{"lat":1189,"lon":1188},{"facility":1192,"status":68,"city":1184,"state":50,"zip":1193,"country":1175,"countryCode":1176,"cosmosGeoPoint":1194,"geoPoint":1196,"contacts":50},"Taipei Veterans General Hospital.","11217",{"type":75,"coordinates":1195},[1188,1189],{"lat":1189,"lon":1188},{"facility":1198,"status":68,"city":1199,"state":1200,"zip":1201,"country":1202,"countryCode":1203,"cosmosGeoPoint":1204,"geoPoint":1208,"contacts":50},"The Royal Marsden Hospital (Surrey)","Sutton","Queensland","SM2 5PT","United Kingdom","UK",{"type":75,"coordinates":1205},[1206,1207],-0.2,51.35,{"lat":1207,"lon":1206},{"facility":1210,"status":68,"city":1199,"state":1211,"zip":1201,"country":1202,"countryCode":1203,"cosmosGeoPoint":1212,"geoPoint":1214,"contacts":50},"Royal Marsden Hospital","Surrey",{"type":75,"coordinates":1213},[1206,1207],{"lat":1207,"lon":1206},{"facility":1216,"status":68,"city":1217,"state":50,"zip":1218,"country":1202,"countryCode":1203,"cosmosGeoPoint":1219,"geoPoint":1223,"contacts":50},"Queen Elizabeth Hospital","Birmingham","B15 2TH",{"type":75,"coordinates":1220},[1221,1222],-1.89983,52.48142,{"lat":1222,"lon":1221},{"facility":1225,"status":68,"city":1217,"state":50,"zip":1218,"country":1202,"countryCode":1203,"cosmosGeoPoint":1226,"geoPoint":1228,"contacts":50},"University Hospitals Birmingham NHS Foundation Trust",{"type":75,"coordinates":1227},[1221,1222],{"lat":1222,"lon":1221},{"facility":1230,"status":68,"city":1231,"state":50,"zip":1232,"country":1202,"countryCode":1203,"cosmosGeoPoint":1233,"geoPoint":1237,"contacts":50},"The Royal Marsden NHS Foundation Trust","London","SW3 6JJ",{"type":75,"coordinates":1234},[1235,1236],-0.12574,51.50853,{"lat":1236,"lon":1235},{"facility":1239,"status":68,"city":1231,"state":50,"zip":1240,"country":1202,"countryCode":1203,"cosmosGeoPoint":1241,"geoPoint":1243,"contacts":50},"Sarah Cannon Research Institute","W1G 6AD",{"type":75,"coordinates":1242},[1235,1236],{"lat":1236,"lon":1235},{"facility":1245,"status":68,"city":1231,"state":50,"zip":1246,"country":1202,"countryCode":1203,"cosmosGeoPoint":1247,"geoPoint":1249,"contacts":50},"Diagnostic centre","W1G 7AF",{"type":75,"coordinates":1248},[1235,1236],{"lat":1236,"lon":1235},{"facility":1251,"status":68,"city":1231,"state":50,"zip":1252,"country":1202,"countryCode":1203,"cosmosGeoPoint":1253,"geoPoint":1255,"contacts":50},"The Harley Street Clinic","W1G 8BJ",{"type":75,"coordinates":1254},[1235,1236],{"lat":1236,"lon":1235},{"facility":1257,"status":68,"city":1231,"state":50,"zip":1258,"country":1202,"countryCode":1203,"cosmosGeoPoint":1259,"geoPoint":1261,"contacts":50},"Radiology","W1G 8PP",{"type":75,"coordinates":1260},[1235,1236],{"lat":1236,"lon":1235},{"type":1263,"investigatorFullName":50,"investigatorTitle":50,"investigatorAffiliation":50,"oldNameTitle":50,"oldOrganization":50},"SPONSOR","100392410","phase-1-a-study-of-sigvotatug-vedotin-in-advanced-solid-tumors-100392410",false,"NCT04389632","A Study of Sigvotatug Vedotin in Advanced Solid Tumors","A Phase 1 Study of Sigvotatug Vedotin in Advanced Solid Tumors","Inclusion Criteria:\n\n* Disease indication\n\n  * Participants must have histologically or cytologically confirmed metastatic or unresectable solid malignancy within one of the tumor types listed below (dependent on study part).\n\n    * Non-small cell lung cancer (NSCLC)\n    * Head and neck squamous cell cancer (HNSCC)\n    * Advanced HER2-negative breast cancer\n    * Esophageal squamous cell carcinoma (ESCC)\n    * Esophageal\u002FGastro-esophageal junction adenocarcinoma (EAC\u002FGEJ)\n    * Cutaneous squamous cell cancer (cSCC)\n    * Exocrine pancreatic adenocarcinoma\n    * Bladder cancer\n    * Cervical cancer\n    * Gastric cancer\n    * High grade serous ovarian cancer (HGSOC)\n  * Part A only: Participants must have disease that is relapsed or refractory or be intolerant to standard-of-care therapies and should have no appropriate standard-of-care therapeutic options.\n  * Part B only: Participants must have disease that is relapsed or refractory or be intolerant to standard-of-care therapies. Participants must have received platinum-based therapy and a PD-1\u002FPD-(L)1 inhibitor, if applicable and available.\n  * Part C only: For pembrolizumab combination cohorts, participants must be eligible for pembrolizumab per local standard of care. For pembrolizumab with cisplatin or carboplatin, participants must be eligible for both pembrolizumab and the platinum agent per local standard of care. Participants must be treatment naïve for locally advanced or metastatic systemic therapy (prior definitively intended or \\[neo\\]adjuvant therapy is allowed).\n  * Part D only: Participants must be treatment naïve for locally advanced or metastatic systemic therapy.\n* Participants enrolled in the following study parts should have a tumor site accessible for biopsy and agree to biopsy as follows:\n\n  * Disease-specific expansion cohorts (Part B and Part D): A baseline fresh tumor biopsy is required. An archival biopsy collected within 90 days prior to first dose of study drug may be used.\n  * Biology expansion cohort: pretreatment biopsy and on-treatment (Cycle 1) biopsy\n* An Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1\n* Measurable disease per the RECIST v1.1 at baseline\n\nExclusion Criteria\n\n* History of another malignancy within 3 years before first dose of study drug, or any evidence of residual disease from a previously diagnosed malignancy. Exceptions are malignancies with a negligible risk of metastasis or death.\n* Known active central nervous system metastases. Participants with previously treated brain metastases may participate provided they:\n\n  * are clinically stable for at least 4 weeks prior to study entry after brain metastasis treatment,\n  * have no new or enlarging brain metastases, and\n  * are off of corticosteroids prescribed for symptoms associated with brain metastases for at least 7 days prior to first dose of study drug.\n  * In Part D, participants with untreated, asymptomatic CNS metastases smaller than 1 cm may be enrolled without definitive treatment as long as they have no neurological symptoms, no or minimal surrounding edema, and no requirements for corticosteroids.\n* Carcinomatous meningitis\n* Previous receipt of an MMAE-containing agent or an agent targeting integrin beta-6\n* Pre-existing neuropathy Grade 1 or greater per the National Cancer Institute's Common Terminology Criteria for Adverse Events, version 5.0 (NCI CTCAE v5.0) for Parts C and D cohorts with cisplatin or carboplatin; Grade 2 or greater per the NCI CTCAE v5.0 for all other cohorts\n* Any uncontrolled Grade 3 or higher (per NCI CTCAE v5.0) viral, bacterial, or fungal infection within 2 weeks prior to the first dose of sigvotatug vedotin.\n\n  * Routine antimicrobial prophylaxis is permitted\n* Grade ≥3 pulmonary disease unrelated to underlying malignancy. This includes clinically severe pulmonary function compromise resulting from clinically significant pulmonary illnesses\n* Part C and D: Prior therapy with a PD-1 inhibitor, anti-PD-(L)1, or anti PD-L2 agent or with an agent directed to another stimulatory or co-inhibitory T-cell receptor and was discontinued from that treatment due to a Grade 3 or higher immune-mediated adverse event (IMAE).\n* History of noninfectious interstitial lung disease (ILD) or pneumonitis that required steroids, current ILD or pneumonitis, or suspected ILD or pneumonitis that cannot be ruled out by imaging at screening\n* Known diffusing capacity of the lung for carbon monoxide (DLCO; adjusted for hemoglobin) \\\u003C50% predicted\n* Investigator site staff directly involved in the conduct of the study and their family members, site staff otherwise supervised by the investigator, and sponsor and sponsor delegate employees directly involved in the conduct of the study and their family members.","ALL","18 Years",{"count":1274,"type":1275},1006,"ESTIMATED","INTERVENTIONAL",[1278],"PHASE1","This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it is safe for people who have solid tumors. It will study sigvotatug vedotin to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether sigvotatug vedotin works to treat solid tumors.\n\nThe study will have four parts.\n\n* Part A of the study will find out how much sigvotatug vedotin should be given to participants.\n* Part B will use the dose found in Part A to find out how safe sigvotatug vedotin is and if it works to treat solid tumors.\n* Part C of the study will find out how safe sigvotatug vedotin is in combination with these other drugs.\n* Part D will include people who have not received treatment. This part of the study will find out how safe sigvotatug vedotin is in combination with these other drugs and if these combinations work to treat solid tumors.\n* In Parts C and D, participants will receive sigvotatug vedotin with either:\n\n  * Pembrolizumab or,\n  * Pembrolizumab and carboplatin, or\n  * Pembrolizumab and cisplatin.",[1281,1282,1283,1284,1285,1286,1287,1288,1289,1290,1291,1292],"Carcinoma, Non-Small Cell Lung","Squamous Cell Carcinoma of Head and Neck","HER2 Negative Breast Neoplasms","Esophageal Squamous Cell Carcinoma","Esophageal Adenocarcinoma","Gastroesophageal Junction Adenocarcinoma","Ovarian Neoplasms","Cutaneous Squamous Cell Cancer","Exocrine Pancreatic Adenocarcinoma","Urinary Bladder Neoplasms","Uterine Cervical Neoplasms","Stomach Neoplasms",[1294,1295,1296,1297,1298,1299,1300,1301,1302,1303,1304,1305,1306,1307,1308,1309],"NSCLC","HNSCC","cSCC","ESCC","EAC","GEJ","HGSOC","Advanced HER2-Negative Breast Cancer","High Grade Serous Ovarian Cancer","Non-Small Cell Lung Cancer","Head and Neck Squamous Cell Cancer","Esophageal Cancer","Bladder Cancer","Cervical Cancer","Gastric Cancer","Seattle Genetics","2026-05-08",{"date":1312,"type":1313},"2026-05-11","ACTUAL",{"date":1315,"type":1313},"2020-06-08",{"date":1317,"type":1275},"2029-03-22",{"name":1319,"class":6},"Seagen, a wholly owned subsidiary of Pfizer",159]