[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100495366":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":56,"collaborators":20,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":20,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":20,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":35,"whyStopped":20,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"The University of The West Indies","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment","EXPERIMENTAL","Participants with tinea versicolor who will have a treatment site selected. We will leave untreated areas to serve as \"internal controls\". Participants will apply cream to the designated areas but leave non-designated untreated. At follow up visits we will do fungal scrapings, visual examination and Wood's lamp evaluation of treatment and non-treatment areas",[13],"Drug: 20% Cassia alata cream",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","20% Cassia alata cream","Thin layer of cassia alata cream to cover treatment area. 1 finger tip unit will cover roughly 4 x 4 inch area. Number of FTU determined by investigators depending on rough size of area to be treated",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Jonathan D Ho, MBBS, D.Sc","The University of the West Indies, Mona Campus","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Marvin Reid, MB Bs PhD","CONTACT","8763812939","marvin.reid@uwimona.edu.jm",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"University of the West Indies, Mona","RECRUITING","Kingston","Other","007","Jamaica","JM",{"type":42,"coordinates":43},"Point",[44,45],-76.79358,17.99702,{"lat":45,"lon":44},[48,51,54],{"name":49,"role":29,"phone":50,"phoneExt":20,"email":31},"Marvin Reid, MB BS","8769271884",{"name":52,"role":53,"phone":20,"phoneExt":20,"email":20},"Chelsea Roye, MBBS","SUB_INVESTIGATOR",{"name":55,"role":53,"phone":20,"phoneExt":20,"email":20},"Jheanelle Foster, MBBS",{"type":57,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100495366","phase-1-a-study-of-the-clinical-efficacy-and-safety-of-20-cassia-alata-extract-against-tinea-versicolor-100495366",false,"NCT05730244","A Study of the Clinical Efficacy and Safety of 20% Cassia Alata Extract Against Tinea Versicolor","A Single Arm No-treatment Self-controlled Trial Pilot Study Evaluating the Clinical Efficacy and Safety Profile of 20% Cassia Alata Cream Against Tinea Versicolor","Inclusion Criteria:\n\n* Patients aged 18-89 of either sex\n* Clinical features suggestive of tinea versicolor AND Microscopic confirmation using skin scraping stains with chlorazol black preparation AND\u002FOR Wood's lamp fluorescence\n* No treatment for versicolor in the preceding 4 weeks\n* No contraindications to the application of C.alata cream including\n* No history of allergy to C. alata\n* No history of preservative allergy\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>89 years\n* Pregnant females\n* History of hypersensitivity to C. alata or preservative\n* Treatment within 4 weeks prior to enrollment\n* Lesions which do not meet the diagnostic criteria of tinea versicolor","ALL","18 Years","89 Years",{"count":69,"type":70},20,"ESTIMATED","INTERVENTIONAL",[73],"PHASE1","The goal of this clinical trial is to establish the efficacy of Cassia alata extract as a cream form in treating tinea versicolor (liver spots\u002Fshifting clouds). The main questions the study aims to answer are:• Does the use of this extract help resolve tinea versicolor better than no treatment? Does the use of this cream have significant side effects i.e, is it safe? Participants will be asked to treat a designated area while leaving additional areas untreated. 1-2 finger tip units of cream will be applied to the treatment site twice daily at least 8 hours apart. Participants will attend the trial clinic every 4 weeks for 12 weeks.",[76,77],"Tinea Versicolor","Pityriasis Versicolor",[79,80,81],"Tinea Versicolor,","Cassia alata extract","Pityriasis versicolor","2025-11-14",{"date":84,"type":85},"2025-11-19","ACTUAL",{"date":87,"type":85},"2025-03-01",{"date":89,"type":70},"2026-12-30",{"name":5,"class":6},1]