[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616348":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":30,"locations":36,"responsibleParty":55,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":73,"conditions":74,"keywords":79,"overallStatus":39,"whyStopped":11,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Adia Med of Winter Park LLC","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Glutathione with Stem Cells","EXPERIMENTAL",null,[13,14],"Biological: Umbilical Cord Blood-Derived Stem Cells and Exosomes","Drug: Glutathione",{"label":16,"type":17,"description":11,"interventionNames":18},"Glutathione Only","ACTIVE_COMPARATOR",[14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BIOLOGICAL","Umbilical Cord Blood-Derived Stem Cells and Exosomes","Intravenous infusion of cryopreserved allogeneic umbilical cord blood-derived product containing viable mononuclear cells (including hematopoietic and mesenchymal stem\u002Fstromal cells) and exosomes.",[9],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"DRUG","Glutathione","Reduced L-glutathione administered Intravenous infusion once monthly for 3 months (Phase I)",[16,9],[31],{"name":32,"role":33,"phone":34,"phoneExt":11,"email":35},"Larry Powalisz","CONTACT","3217880850","research@adiamed.com",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Adia Med Of Winter Park","RECRUITING","Winter Park","Florida","32789","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-81.33924,28.6,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":54,"phoneExt":11,"email":35},"Dr Thomas MD, MD","3212312843",{"type":56,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100616348","phase-1-adia-med-of-winter-park-llc-autism-spectrum-disorder-research-study-100616348",false,"NCT07304440","Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study","Inclusion Criteria:\n\n* Age 3-12 years\n* Confirmed ASD diagnosis (DSM-5 criteria, supported by ADOS-2)\n* Parent\u002Fguardian willingness to consider experimental treatments and comply with study requirements\n* Ability to attend all scheduled visits\n* Able to meet study cost requirements ($12,000 study fee plus bloodwork costs, if applicable) as described in the informed consent\n\nExclusion Criteria:\n\n* Severe allergies to study products\n* Significant uncontrolled medical conditions\n* Pregnancy or breastfeeding (if applicable)\n* Participation in another interventional trial within 30 days\n* Prior stem cell or glutathione therapy: History of stem cell therapy (including umbilical cord blood-derived stem cells or exosomes) or glutathione therapy (intravenous or topical) at any time prior to screening","ALL","3 Years","12 Years",{"count":67,"type":68},100,"ESTIMATED","INTERVENTIONAL",[71,72],"PHASE1","PHASE2","This 24-month study is testing whether adding AdiaVita, an umbilical cord blood-derived stem cell and exosome product, to glutathione therapy helps improve autism symptoms in children ages 3-12 more than glutathione alone. Children will be randomly placed into one of two groups for the first three months: one group receives glutathione only, and the other receives glutathione plus monthly intravenous AdiaVita infusions. Both groups also use topical glutathione cream twice daily at home. Autism symptoms will be tracked over two years using the Autism Treatment Evaluation Checklist (ATEC) filled out by parents and by therapists or teachers. Safety, side effects, quality of life, and overall well-being will be closely monitored through regular clinic visits, physical exams, blood tests, and adverse event reporting. After the initial three-month phase, children who received glutathione alone may cross over to receive AdiaVita infusions at no additional cost if safety checks at month 6 are satisfactory. Approximately 100 children with a confirmed autism diagnosis from the Central Florida area will take part. Participation is completely voluntary, and families may withdraw at any time.",[75,76,77,78],"Autism Spectrum Disorder","Autism","ASD","Autism Spectrum Disorder (ASD)",[27,80,81,82,83,84,85,76,75,77,86,87,88,89,90,91,92,93],"Intravenous glutathione","Glutathione therapy","Antioxidant therapy","Oxidative stress","Immune modulation","Anti-inflammatory therapy","Autism symptoms","Stem cell therapy","MSCs","Mesenchymal stem cells","Regenerative medicine","Cellular therapy","Hematopoietic stem cells (HSCs)","Allogeneic stem cells","2026-06-16",{"date":96,"type":97},"2026-06-17","ACTUAL",{"date":99,"type":97},"2026-05-01",{"date":101,"type":68},"2028-06-15",{"name":5,"class":6},1]