[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100407761":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":47,"centralContacts":51,"locations":57,"responsibleParty":76,"collaborators":78,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":55,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":55,"enrollmentInfo":92,"targetDuration":55,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":55,"overallStatus":60,"whyStopped":55,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm I ( Health Volunteer MRI)","ACTIVE_COMPARATOR","Healthy volunteers undergo MRI over 30 minutes.",[13],"Procedure: Magnetic Resonance Imaging",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm II (Thyroid Cancer Patient and other malignancies of the head and neck hpMRI)","EXPERIMENTAL","Patients with thyroid cancer and other malignancies of the head and neck undergo hpMRI over 30 minutes at baseline, and at 1 week after the initiation of treatment. During the scan, patients also receive hyperpolarized 13-C-pyruvate IV over 30 seconds and may receive a standard MRI contrast agent at the discretion of the treating physician.",[19,13],"Drug: Hyperpolarized Carbon C 13 Pyruvate",[21,29,43],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Hyperpolarized Carbon C 13 Pyruvate","Given IV",[15],[27,28],"Hyperpolarized 13C-Pyruvate","Hyperpolarized Pyruvate (13C)",{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"PROCEDURE","Magnetic Resonance Imaging","Undergo MRI",[9],[35,36,37,38,39,40,41,42],"Magnetic Resonance Imaging Scan","Medical Imaging, Magnetic Resonance \u002F Nuclear Magnetic Resonance","MR Imaging","MRI","MRI Scan","NMR Imaging","NMRI","Nuclear Magnetic Resonance Imaging",{"type":30,"name":31,"description":44,"armGroupLabels":45,"otherNames":46},"Undergo hpMRI",[15],[35,36,37,38,39,40,41,42],[48],{"name":49,"affiliation":5,"role":50},"Stephen Y Lai","PRINCIPAL_INVESTIGATOR",[52],{"name":49,"role":53,"phone":54,"phoneExt":55,"email":56},"CONTACT","713-792-6528",null,"sylai@mdanderson.org",[58],{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"M D Anderson Cancer Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":67,"coordinates":68},"Point",[69,70],-95.36327,29.76328,{"lat":70,"lon":69},[73,75],{"name":74,"role":53,"phone":54,"phoneExt":55,"email":55},"Stephen Y. Lai",{"name":74,"role":50,"phone":55,"phoneExt":55,"email":55},{"type":77,"investigatorFullName":55,"investigatorTitle":55,"investigatorAffiliation":55,"oldNameTitle":55,"oldOrganization":55},"SPONSOR",[79],{"name":80,"class":81},"National Cancer Institute (NCI)","NIH","100407761","phase-1-an-investigational-scan-hpmri-for-monitoring-treatment-response-in-patients-with-thyroid-cancer-and-other-malignancies-of-the-head-and-neck-undergoing-radiation-therapy-andor-systemic-therapy-100407761",false,"NCT04589624","An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and\u002For Systemic Therapy","Pilot Study of Metabolic Guidance for Therapy in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck","Inclusion Criteria:\n\n* Be willing and able to provide informed consent\n* Be informed of the investigational nature of this study\n* Be diagnosed with thyroid cancer and other malignancies of the head and neck with intent for treatment\n\nExclusion Criteria:\n\n* Have a history of severe claustrophobia\n* Have electrically, magnetically or mechanically activated implants that would preclude magnetic resonance imaging (MRI)\n* Have a history of cardiac arrhythmia\n* Have an allergy to Gadavist intravenous contrast\n* Estimated glomerular filtration rate (eGFR) \\\u003C 30\n* If female, be pregnant or breast feeding at time of consent",true,"ALL","18 Years",{"count":93,"type":94},42,"ESTIMATED","INTERVENTIONAL",[97],"PHASE1","This trial investigates whether hyperpolarized magnetic resonance imaging (hpMRI) can predict treatment response in patients with thyroid cancer and other malignancies of the head and neck undergoing radiation therapy and\u002For receiving systemic therapy before surgery. An hpMRI is like a standard MRI but involves the use of an imaging contrast agent called hyperpolarized 13-C-pyruvate. Diagnostic procedures, such as hpMRI, may predict a patient's response to treatment and may help plan the best treatment.",[100],"Thyroid Gland Carcinoma","2026-05-19",{"date":103,"type":104},"2026-05-22","ACTUAL",{"date":106,"type":104},"2020-08-12",{"date":108,"type":94},"2027-05-31",{"name":5,"class":6},1]