[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618372":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":27,"centralContacts":28,"locations":34,"responsibleParty":47,"collaborators":27,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":27,"studyType":66,"phases":67,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":75,"whyStopped":27,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":64},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo effect on post operative pain after TKA","EXPERIMENTAL","The patient will be gaven an empty pill and we will score the pain postoperative and if it has effect on postoperative pain or not",[13],"Drug: Effect of two different drugs on post operative pain after TKA",{"label":15,"type":10,"description":16,"interventionNames":17},"Palmetoyelethenolamide effect on post operative pain after TKA","The patient will be gaven an pill containing palmytoiethenolamide and we will score the pain postoperative and if it has effect on postoperative pain or not",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Effect of two different drugs on post operative pain after TKA","Effect of preoperative dose of palmetoyelethenolamide in post-op pain in patient undergoing Total Knee Replacement",[15,9],[25,26],"Palmetoyelethenolamide","Placebo pill",null,[29],{"name":30,"role":31,"phone":32,"phoneExt":27,"email":33},"Abdelrahman Gaber Elkhareeb, Resident","CONTACT","201050081327","AbdElrahman.15235731@med.aun.edu.eg",[35],{"facility":36,"status":27,"city":37,"state":38,"zip":27,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":27},"Assiut university","Asyut","Assuit","Egypt","EG",{"type":42,"coordinates":43},"Point",[44,45],31.18368,27.18096,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"SPONSOR_INVESTIGATOR","Abdelrahman Gaber Sayed Elkhateeb","Assistant lecturer","100618372","phase-1-analgesic-efficacy-of-pre-operative-dose-of-palmitoylethanolamide-in-patients-undergoing-total-knee-arthroplasty-100618372",false,"NCT07330765","Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplasty","Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplasty, A Randomized Double-Blinded Controlled Trial.","Total knee","Inclusion Criteria:\n\nPatients Undergoing Total Knee Replacement from 40 years old to 80 years old\n\nExclusion Criteria\n\n* Rheumatoid Arthritis\n\n  * History of Renal impairment\n  * Any complications of surgery as( iatrogenic fractures -patient with low bone quality that needs long stem prosthesis -patient with depressed tibial plateau that needs graft )\n  * Patients refused to be enrolled in the study",true,"ALL","40 Years","80 Years",{"count":64,"type":65},1,"ESTIMATED","INTERVENTIONAL",[68,69],"PHASE1","PHASE2","Analgesic Efficacy of Pre-Operative Dose of palmitoylethanolamide in Patients Undergoing total Knee Arthroplasty, A Randomized Double-Blinded Controlled Trial.",[72],"Total Knee Replacement",[74],"Post operative pain","NOT_YET_RECRUITING","2026-01-05",{"date":78,"type":79},"2026-01-09","ACTUAL",{"date":81,"type":65},"2026-01-13",{"date":83,"type":65},"2027-10-13",{"name":49,"class":6}]