[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597748":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":55,"collaborators":34,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":34,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":34,"studyType":71,"phases":72,"briefSummary":75,"conditions":76,"keywords":34,"overallStatus":42,"whyStopped":34,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"68Ga-FAPI PET\u002FCT in Sjögren's Syndrome","EXPERIMENTAL","All patients diagnosed with Sjögren's syndrome underwent 68Ga-FAPI PET\u002FCT.",[13],"Drug: 68Ga-FAPI",{"label":15,"type":10,"description":16,"interventionNames":17},"68Ga-FAPI PET\u002FCT in tumor patients","Patients with tumors such as lung cancer and breast cancer, who had been excluded for Sjögren's syndrome, underwent 68Ga-FAPI PET\u002FCT.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","68Ga-FAPI","Intravenous injection of one dosage of 18.5-22.2MBq (0.5-0.6 mCi)\u002FKg 68Ga-FAPI. Tracer doses of 68Ga- FAPI will be used to image lesions of Sjögren's syndrome by PET\u002F CT.",[9,15],[25],"68Ga-Fibroblast activation protein Inhibitor",[27],{"name":28,"affiliation":5,"role":29},"Zhaohui Zhu, MD","STUDY_CHAIR",[31,36],{"name":28,"role":32,"phone":33,"phoneExt":34,"email":35},"CONTACT","13611093752",null,"13611093752@163.com",{"name":37,"role":32,"phone":38,"phoneExt":34,"email":39},"Jiarou Wang, MD","13628477019","ChristinaWang97@163.com",[41],{"facility":5,"status":42,"city":43,"state":34,"zip":34,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Beijing","China","CN",{"type":47,"coordinates":48},"Point",[49,50],116.39723,39.9075,{"lat":50,"lon":49},[53,54],{"name":28,"role":32,"phone":33,"phoneExt":34,"email":35},{"name":37,"role":32,"phone":38,"phoneExt":34,"email":39},{"type":56,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR","100597748","phase-1-analyse-of-inflammatory-activity-of-sjgrens-syndrome-on-68ga-fapi-pet-ct-100597748",false,"NCT07062523","Analyse of Inflammatory Activity of Sjögren's Syndrome on 68Ga-FAPI PET-CT","Application of [68Ga]Ga-FAPI-04 PET\u002FCT in the Assessment of Inflammatory Activity in Sjögren's Syndrome","Inclusion Criteria:\n\n* Age 18-80 years;\n* Fulfillment of the 2016 ACR-EULAR Classification Criteria for pSS at enrollment. OR diagnosis of a solid tumor scheduled for FAPI PET imaging\n\nExclusion Criteria:\n\n* Combined with tumors or other connective tissue diseases (for SS group);\n* Patients who are currently using hormones\u002Fbiological agents (for both groups)；\n* Pregnancy or lactation",true,"ALL","18 Years","80 Years",{"count":69,"type":70},60,"ESTIMATED","INTERVENTIONAL",[73,74],"PHASE1","PHASE2","Sjögren's syndrome (SS) is a chronic autoimmune disease primarily affecting the salivary and lacrimal glands, leading to symptoms of dryness. Assessing the inflammatory activity is crucial for guiding treatment. Fibroblast activation protein (FAPI) PET is an emerging imaging technique increasingly used for evaluating various inflammations and tumors. Thus this prospective study is going to investigate the uptake characteristics of FAPI PET in Sjögren's syndrome and evaluate its potential in assessing inflammatory activity to guide clinical treatment. A control group of tumor patients undergoing FAPI PET imaging will be included to compare FAPI uptake patterns between autoimmune inflammation and neoplasia.",[77],"Sjogren's Syndrome","2025-11-23",{"date":80,"type":81},"2025-12-01","ACTUAL",{"date":83,"type":81},"2024-07-01",{"date":80,"type":70},{"name":5,"class":6},1]