[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604020":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":31,"centralContacts":36,"locations":41,"responsibleParty":58,"collaborators":22,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":22,"eligibilityCriteria":67,"healthyVolunteers":64,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":22,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":44,"whyStopped":22,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"First Hospital of China Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Tumor population","EXPERIMENTAL","PET imaging will begin 30 +\u002F-10 minutes, 60 +\u002F-15 minutes and 120 +\u002F-20 minutes after injection of 68Ga-FXX489 or 68Ga-FAP-2286 or 18F-FDG.",[13,14,15],"Drug: 68Ga-FXX489","Procedure: Positron Emission Tomography (PET) imaging","Drug: Gallium-68 labelled (68Ga-) FAP-2286",[17,23,28],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"DRUG","68Ga-FXX489","The dose will be 3 to 8 millicurie (mCi) +\u002F- 10% given intravenously at a single time prior to imaging.",[9],null,{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":22},"PROCEDURE","Positron Emission Tomography (PET) imaging","Participants will be scanned for approximately 30 to 45 minutes.",[9],{"type":18,"name":29,"description":20,"armGroupLabels":30,"otherNames":22},"Gallium-68 labelled (68Ga-) FAP-2286",[9],[32],{"name":33,"affiliation":34,"role":35},"Xuena Li","Department of Nuclear Medicine, The First Hospital of China Medical University","STUDY_DIRECTOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":22,"email":40},"CONTACT","0086-18040099351","lixuenacmunm@163.com",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"The First Hospital of China Medical University","RECRUITING","Shenyang","Liaoning","110001","China","CN",{"type":51,"coordinates":52},"Point",[53,54],123.43278,41.79222,{"lat":54,"lon":53},[57],{"name":33,"role":38,"phone":39,"phoneExt":22,"email":40},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"SPONSOR_INVESTIGATOR","Yi Tian","Sponsor Investigator","100604020","phase-1-application-of-ga-fxx489-nns309-petct-imaging-in-diagnosis-of-tumor-diseases-100604020",false,"NCT07144085","Application of ⁶⁸Ga-FXX489 (NNS309) PET\u002FCT Imaging in Diagnosis of Tumor Diseases.","Inclusion Criteria:\n\n1. Patients with a high suspicion of oncological diseases.\n2. Age: 18-80 years, no gender restriction, able to express themselves independently, and willing to participate in this study with a signed informed consent form.\n\nExclusion Criteria:\n\n1. Failure to sign the informed consent form.\n2. Severe visual or auditory impairment, cognitive disorders, or patients with claustrophobia who cannot communicate effectively.\n3. Severe cardiac dysfunction, cardiac function class III-IV.\n4. Renal failure (serum creatinine level \\> 1.2 mg\u002Fdl).\n5. Allergy to alcohol.\n6. Use of drugs within 1 week prior to the examination that can cause a disulfiram-like reaction with alcohol, such as penicillins, cephalosporins, or cefotetan.\n7. Known pregnancy.","ALL","18 Years","80 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"PHASE1","A new radiotracer, 68Ga-FXX489 (NNS309), has been developed for tracking fibroblast activation protein (FAP) and visualizing the tumor stroma. The purpose of the study is to explore the diagnostic value of 68Ga-FXX489 (NNS309) PET\u002FCT imaging in oncological diseases, to assess its safety, imaging characteristics, and biodistribution after administration.",[79,80],"Tumor","Metastatic Cancer",[82,83],"FAP","CAF","2026-03-30",{"date":86,"type":87},"2026-04-03","ACTUAL",{"date":89,"type":87},"2025-09-11",{"date":91,"type":73},"2027-07-30",{"name":60,"class":6},1]