[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534311":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":45,"responsibleParty":82,"collaborators":84,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":90,"sex":96,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":31,"studyType":102,"phases":103,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":69,"whyStopped":31,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Virginia Commonwealth University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise Training Intervention","EXPERIMENTAL","The exercise program (ET) is tailored to each participant depending on his initial functional capacity, cardiorespiratory fitness and strength, to achieve ≥150 moderate to vigorous physical activity",[13],"Behavioral: Exercise Training Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Healthy Living Education Control","ACTIVE_COMPARATOR","Educational modules delivered remotely (or manual and telephone call) in a group-based setting to approximately match contact frequency and structure with the ET arm.",[19],"Behavioral: Healthy Living Education",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","5.1. The behavioral ET and HLE interventions will be delivered over 12 weeks. Before starting the study, men will be asked to attend one (1) in-person small group orientation to provide an overview of each intervention arm, familiarize them with web-based and smartphone applications or hard copy manuals for delivery of intervention content, exercise logs, resistance bands, and equipment for strength training.",[9],[26],"Behavioral, Exercise Training",{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Healthy Living Education","During the initial 12 weeks of the study, men randomized to the HLE group will receive educational modules delivered remotely (or manual and telephone call) in a group-based setting to approximately match contact frequency and structure with the ET arm.",[15],null,[33],{"name":34,"affiliation":5,"role":35},"Alexander R Lucas, PhD","PRINCIPAL_INVESTIGATOR",[37,41],{"name":34,"role":38,"phone":39,"phoneExt":31,"email":40},"CONTACT","804 628-6610","Alexander.Lucas@vcuhealth.org",{"name":42,"role":38,"phone":43,"phoneExt":31,"email":44},"Alexandra Marshall, MS","804 628-1215","lara.marshall@vcuhealth.org",[46,67],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Richmond Veterans Affairs Medical Center","NOT_YET_RECRUITING","Richmond","Virginia","23249","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-77.46026,37.55376,{"lat":58,"lon":57},[61,64,66],{"name":34,"role":38,"phone":62,"phoneExt":31,"email":63},"804-628-6610","Alexander.Lucas2@va.gov",{"name":65,"role":38,"phone":43,"phoneExt":31,"email":44},"Alexandra L Marshall, MS",{"name":34,"role":35,"phone":31,"phoneExt":31,"email":31},{"facility":68,"status":69,"city":49,"state":50,"zip":70,"country":52,"countryCode":53,"cosmosGeoPoint":71,"geoPoint":73,"contacts":74},"Virginia Commonwealth University Massey Cancer Center","RECRUITING","23298",{"type":55,"coordinates":72},[57,58],{"lat":58,"lon":57},[75,78,80],{"name":76,"role":38,"phone":31,"phoneExt":31,"email":77},"Alexandra Marshall","marshallla@vcu.edu",{"name":79,"role":38,"phone":62,"phoneExt":31,"email":40},"Alexander Lucas, PhD",{"name":81,"role":35,"phone":31,"phoneExt":31,"email":31},"Alexander Lucas, Ph.D",{"type":83,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR",[85],{"name":86,"class":87},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100534311","phase-1-behavioral-exercise-training-to-reduce-cardiovascular-disease-risk-100534311",false,"NCT06237179","Behavioral Exercise Training to Reduce Cardiovascular Disease Risk","Behavioral Exercise Training to Reduce Cardiovascular Disease Risk in Men Undergoing Androgen Deprivation Therapy (EXTRA-PC)","EXTRA-PC","Inclusion Criteria:\n\n* Be diagnosed with stage II\u002FIII\u002FIV prostate cancer\n* Be currently undergoing treatment with ADT (intermittent or prolonged)\n* Have completed local curative-intent treatment, including prostatectomy or definitive radiation;\n* Be \\>40 years of age up to 85;\n* Be willing to sign an informed consent with HIPAA authorization form;\n* Not have any hearing or sight impairments that result in the inability to use the telephone or hear normal conversation;\n* Must be able to join an intervention group by personal computer, smartphone or telephone call and should agree to recording of an interview;\n* Be without any serious medical condition that precludes safe participation in an exercise program;\n* Speak English\n\nExclusion Criteria:\n\n* Be unable to undergo MRI (i.e., ferromagnetic materials in body, inability to lie flat, claustrophobia);\n* Have contraindications to exercise testing;\n* Have pre-existing overt cardiovascular disease\u002Fheart failure;\n* Active illness\u002Finfection;\n* Hemoglobin \\\u003C 7.0 grams\u002FdL\n* Platelet count \\\u003C 10 x 109\u002FL","MALE","40 Years","85 Years",{"count":100,"type":101},60,"ESTIMATED","INTERVENTIONAL",[104,105],"PHASE1","PHASE2","To test the preliminary effectiveness of a home-based exercise training (ET) intervention to improve exercise capacity (VO2 peak \\& 6-minute walk distance \\[6MWD\\]) among prostate cancer (PC) patients compared to controls receiving healthy living education (HLE) at 12 weeks.",[108,109],"Prostate Cancer","Supportive Care",[108,109,111],"Exercise","2026-02-26",{"date":114,"type":115},"2026-03-02","ACTUAL",{"date":117,"type":115},"2024-02-21",{"date":119,"type":101},"2028-01-31",{"name":5,"class":6},2]