[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587215":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":40,"locations":26,"responsibleParty":49,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":26,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":80,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":26},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"metapex pulpectomy","ACTIVE_COMPARATOR","Single-visit pulpectomy using Metapex, . Calcium hydroxide-iodoform mixture (Metapex) is an ideal pulpal filling material for primary teeth.",[13],"Drug: Metapex",{"label":15,"type":16,"description":17,"interventionNames":18},"3Mixtatin Pulpotomy","EXPERIMENTAL","pulpotomy with 3 mixtatin (triple antibiotic paste of (Metronidazole, cefixime, and Ciprofloxacin mixed with simvastatin ) applied in the vital pulp therapy",[19],"Drug: 3Mixtatin",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Metapex","Pulpectomy using Metapex",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"3Mixtatin","pulpotomy treatment when applying 3mixture of antibiotic (Metronidazole, cefixime, and Ciprofloxacin) along with simvastatin",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Osama Ibrahim El Shahawy, Professor","Professor of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University","STUDY_DIRECTOR",{"name":37,"affiliation":38,"role":39},"Marwa Aly Fouad, Associate professor","Associate Professor of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University","STUDY_CHAIR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":26,"email":45},"Nora Mohamed Mosaad, PHD researcher","CONTACT","00201000921189","nora.mosaad@dentistry.cu.edu.eg",{"name":47,"role":43,"phone":26,"phoneExt":26,"email":48},"Marwa Aly Fouad, Associate Professor","marwaaly2003@yahoo.com",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Nora Mohamed Mosaad Hussien","Pedodontist, Cairo University","100587215","phase-1-comparison-of-3mixtatin-pulpotomy-and-metapex-pulpectomy-in-primary-molars-with-irreversible-pulpitis-100587215",false,"NCT06925490","Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis","Clinical and Radiographic Evaluation of Pulpotomy Using 3Mixtatin Versus Pulpectomy Using Metapex in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis in Children Aged 4 to 9 Years: A Randomized Clinical Trial.","Inclusion Criteria:\n\n* Children aged from 4 to 9 years with vital primary molars showing signs of irreversible pulpitis.\n* Children with spontaneous pain lasting a few seconds to several hours.\n* Pain is intensified by thermal stimulus and persists after its removal.\n* Pulp hemorrhage after performing access cavity and deroofing of pulp chamber showing reddish pink healthy pulp tissue.\n* Radicular pulp health is verified by achieving hemostasis within eight minutes of compression using a cotton pellet with 5% sodium hypochlorite.\n* Absence of peri-apical or inter-radicular radiolucency, widening of periodontal ligament space, internal or external root resorption.\n\nExclusion Criteria:\n\n* Unrestorable primary molars.\n* Primary molars with uncontrolled pulp hemorrhage or pulp necrosis.\n* Medically compromised patients who have systemic disease.\n* Uncooperative children who refuse treatment.\n* Children whose parents are unwilling to place stainless steel crowns.\n* Children whose parents or caregivers refuse to participate in the study or are unable to attend follow-up visits.",true,"ALL","4 Years","9 Years",{"count":65,"type":66},50,"ESTIMATED","INTERVENTIONAL",[69],"PHASE1","The present study aims to evaluate the clinical and radiographic success of pulpotomy using 3Mixtatin versus pulpectomy using Metapex in primary molars with irreversible pulpitis in children aged 4 to 9 years.",[72,73,74],"Irreversible Pulpitis","Primary Teeth","Pulp Disease, Dental",[28,76,77,78,79],"irreversible pulpitis","metapex","pulpectomy","pulpotomy","NOT_YET_RECRUITING","2025-04-25",{"date":83,"type":84},"2025-04-27","ACTUAL",{"date":86,"type":66},"2025-06",{"date":88,"type":66},"2026-10",{"name":5,"class":6}]