[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619088":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":28,"locations":23,"responsibleParty":34,"collaborators":23,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":41,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":23,"enrollmentInfo":45,"targetDuration":23,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":57,"whyStopped":23,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":23},{"fullName":5,"class":6},"University of Minnesota","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CR-DBS","ACTIVE_COMPARATOR","Randomized to either T-DBS occurring first or CR-DBS occurring first (50\u002F50 chance of being assigned to either, but will be assessing both)",[13],"Device: DBS",{"label":15,"type":10,"description":11,"interventionNames":16},"T-DBS",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"DEVICE","DBS","Deep Brain Stimulation",[9,15],null,[25],{"name":26,"affiliation":5,"role":27},"Jing Wang, PhD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":23,"email":33},"Marina Bryants, CCRP, BS","CONTACT","612-624-3035","bryan371@umn.edu",{"type":35,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100619088","phase-1-coordinated-reset-deep-brain-stimulation-for-parkinsons-disease-100619088",false,"NCT07340073","Coordinated Reset Deep Brain Stimulation for Parkinson's Disease","CR DBS PD","Inclusion Criteria:\n\n* Diagnosis of Idiopathic Parkinson's Disease\n* Minimum age of 21 years old\n* Will be or has been implanted with the Boston Scientific Vercise Genus Rechargeable DBS system\n\nExclusion Criteria:\n\n* History of musculoskeletal disorders that affect movement of the limbs\u002Fgait\n* Other significant neurological disorder\n* Significant psychiatric disorder\n* History of dementia or cognitive impairment that precludes them from getting DBS surgery or per study staff judgment, MacCAT-CR assessment does not deduce that the participant has capacity to consent\n* Other significant medical disorder that could impede study participation\n* Pregnant women","ALL","21 Years",{"count":46,"type":47},24,"ESTIMATED","INTERVENTIONAL",[50],"PHASE1","Deep brain stimulation (DBS) is a surgical implant procedure for the treatment of Parkinson's Disease (PD) utilizing medical devices approved by the FDA. A novel approach to current DBS approaches is called \"Coordinated Reset\" DBS (CR-DBS) which uses different patterns of stimulation at lower currents and can address the limitations of traditional DBS (T-DBS) that uses continuous high amplitude and high frequency stimulation. This study will evaluate the safety and short-term efficacy of CR-DBS in PD. The results from this study will significantly advance the development of CR-DBS for the treatment of PD. Findings in this study will also provide the rationale for further development of this novel DBS approach for other neurological and psychiatric disorders.",[53,21],"Parkinson's Disease (PD)",[55,56],"Deep Brain Simulation","Parkinson's Disease","NOT_YET_RECRUITING","2026-05-18",{"date":60,"type":61},"2026-05-20","ACTUAL",{"date":63,"type":47},"2026-07-01",{"date":65,"type":47},"2031-07-01",{"name":5,"class":6}]