[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645370":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":56,"collaborators":11,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":11,"enrollmentInfo":69,"targetDuration":11,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":82,"whyStopped":11,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Green Tea Extract","EXPERIMENTAL",null,[13],"Dietary Supplement: Green Tea Leaf Extract Decaffeinated",{"label":15,"type":16,"description":11,"interventionNames":17},"Placebo","PLACEBO_COMPARATOR",[18],"Other: Placebo Control",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Green Tea Leaf Extract Decaffeinated","A purified green tea powder containing \\~90% total polyphenols, more than 80% catechins (greater than or equal to 45% EGCG), and less than 1% caffeine.",[9],[26],"Sunphenon 90D",{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":11},"Placebo Control","Rice flour",[15],[32],{"name":33,"affiliation":5,"role":34},"Michael Daniel, PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":11,"email":39},"CONTACT","205-975-0866","michael5@uab.edu",[41],{"facility":5,"status":11,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Birmingham","Alabama","35294","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-86.80249,33.52066,{"lat":51,"lon":50},[54,55],{"name":33,"role":37,"phone":38,"phoneExt":11,"email":39},{"name":33,"role":34,"phone":11,"phoneExt":11,"email":11},{"type":34,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Michael Daniel","Assistant Professor","100645370","phase-1-daily-encapsulated-green-tea-extract-to-mitigate-neuropathic-pain-in-patients-with-established-cancer-associated-neuropathic-pain-100645370",false,"NCT07682324","Daily, Encapsulated, Green Tea Extract to Mitigate Neuropathic Pain in Patients With Established Cancer-Associated Neuropathic Pain","Daily, Encapsulated, Green Tea Extract (GTE) to Mitigate Neuropathic Pain in Patients With Established Cancer-Associated Neuropathic Pain","GTE","Inclusion Criteria:\n\n* 18 years of age or older.\n* Established cancer-associated neuropathic pain.\n* A baseline Douler Neuropathique 4 (DN4) patient-reported neuropathic pain questionnaire score of greater than or equal to 4.\n* A stable pain management medication regimen, with no more than a 10% change in dosage in the past 14 days prior to enrollment.\n* No known allergy to rice or rice flour (basis of placebo).\n\nExclusion Criteria:\n\n* Actively undergoing cancer treatment.\n* Symptoms and\u002For diagnosis of diabetic peripheral neuropathy.\n* Self-describe as consuming more than 3 cups of green tea or matcha beverages on a daily basis.\n* High probability of completing the study and all study-related measures\u002Factivities required by the protocol.","ALL","18 Years",{"count":70,"type":71},20,"ESTIMATED","INTERVENTIONAL",[74],"PHASE1","The overall objective of this study is to test an intervention of green tea extract (GTE) to mitigate neuropathic pain in patients, specifically cancer survivors, receiving supportive palliative care. Our central hypothesis is that daily, oral, encapsulated GTE will mitigate neuropathic pain, as longitudinally measured by the validated Douleur Neuropathique 4 (DN4) and blood protein biomarkers reported to be linked to the development and\u002For chronicity of neuropathic pain.",[77,78],"Neuropathic Pain","Cancer Treatment",[80,65,81],"green tea extract","neuropathic pain","NOT_YET_RECRUITING","2026-06-26",{"date":85,"type":86},"2026-07-02","ACTUAL",{"date":88,"type":71},"2026-09-30",{"date":90,"type":71},"2029-03-01",{"name":5,"class":6},1]