[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100473927":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":19,"locations":26,"responsibleParty":46,"collaborators":18,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":18,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":18,"enrollmentInfo":57,"targetDuration":18,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":29,"whyStopped":18,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Université de Sherbrooke","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Deep brain stimulation","EXPERIMENTAL","Implantation of deep brain stimulation lead within the pontine lesion",[13],"Device: Deep brain stimulation",[15],{"type":16,"name":9,"description":11,"armGroupLabels":17,"otherNames":18},"DEVICE",[9],null,[20],{"name":21,"role":22,"phone":23,"phoneExt":24,"email":25},"Christian Iorio-Morin, MD, PhD, FRCS(C)","CONTACT","819-346-1110","16365","Christian.Iorio-Morin@usherbrooke.ca",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Centre Hospitalier Universitaire de Sherbrooke (CHUS)","RECRUITING","Sherbrooke","Quebec","J1H 5H3","Canada","CA",{"type":36,"coordinates":37},"Point",[38,39],-71.89908,45.40008,{"lat":39,"lon":38},[42],{"name":43,"role":22,"phone":23,"phoneExt":44,"email":45},"Mélodie Grondin-Lavigne, MD MSc candidate","15130","melodie.grondin-lavigne@usherbrooke.ca",{"type":47,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100473927","phase-1-deep-brain-stimulation-for-refractory-trigeminal-neuralgia-with-a-pontine-lesion-100473927",false,"NCT05451251","Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion","Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion: a Pilot Study","Inclusion Criteria:\n\n* Adults of at least 18 years old\n* Refractory trigeminal neuralgia : failure of at least 3 drugs and at least two lesioning surgical interventions (radiosurgery, percutaneous rhizotomy, or open rhizotomy).\n* Pontine lesion proved by MRI in contact with trigeminal nerve tract\n\nExclusion Criteria:\n\n* Absolute contraindication to MRI\n* Medical contraindication to the procedure","ALL","18 Years",{"count":58,"type":59},6,"ESTIMATED","INTERVENTIONAL",[62],"PHASE1","The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis.\n\nThese patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief.\n\nHoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.",[65],"Trigeminal Neuralgia",[67,9,68],"Multiple sclerosis","Pontine lesion","2024-12-06",{"date":71,"type":72},"2024-12-12","ACTUAL",{"date":74,"type":72},"2024-10-15",{"date":76,"type":59},"2026-10",{"name":5,"class":6},1]