[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609538":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":40,"locations":46,"responsibleParty":66,"collaborators":68,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":26,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":26,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single dose of aripiprazole","ACTIVE_COMPARATOR","Single dose of aripiprazole, 10mg administered orally. Participant and administrator will be blinded.",[13],"Drug: Aripiprazole 10 MG",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo dose","PLACEBO_COMPARATOR","A single placebo dose will be administered.",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Aripiprazole 10 MG","The effects of aripiprazole on stuttering and various behavioral and neural outcomes will be studied compared to placebo.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo","Placebo will be compared against aripiprazole for effect on stuttering and various behavioral and neural markers.",[15],[32,35,37],{"name":33,"affiliation":5,"role":34},"John Houde, PhD","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":5,"role":34},"Srikantan Nagarajan, PhD",{"name":38,"affiliation":39,"role":34},"Ludo Max, PhD","University of Washington",[41],{"name":42,"role":43,"phone":44,"phoneExt":26,"email":45},"Natalie Brunwin, MS","CONTACT","4154766888","snl-bil@ucsf.edu",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Biomagentic Imaging Lab","RECRUITING","San Francisco","California","94143","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-122.41942,37.77493,{"lat":59,"lon":58},[62,64,65],{"name":42,"role":43,"phone":63,"phoneExt":26,"email":45},"415-476-6888",{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":36,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":67,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[69,72],{"name":70,"class":71},"National Institute on Deafness and Other Communication Disorders (NIDCD)","NIH",{"name":39,"class":6},"100609538","phase-1-dopamine-and-sensorimotor-function-in-stuttering-100609538",false,"NCT07215884","Dopamine and Sensorimotor Function in Stuttering","Inclusion Criteria:\n\n* native speakers of American English\n* for adults who stutter, presence of stuttering will be confirmed, with onset before age 6 years\n* Normal hearing\n* Ages of 18 to 65 years\n* healthy adults without hearing-language difficulties\n\nExclusion Criteria:\n\n* self-reported speech-language-hearing difficulties other than stuttering\n* self-reported neurological or psychological problems\n* other medications (drugs that affect dopaminergic system and\u002For benzodiazepines)",true,"ALL","18 Years","65 Years",{"count":84,"type":85},40,"ESTIMATED","INTERVENTIONAL",[88],"PHASE1","This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency. This study aims to understand sensorimotor pathways of stuttering and possible interventions.",[91],"Stuttering, Adult",[93,94,95,96,97],"Stuttering","Aripiprazole","Adults with Stuttering","Speech Fluency","Auditory Feedback","2025-10-08",{"date":100,"type":101},"2025-10-14","ACTUAL",{"date":103,"type":101},"2025-09-30",{"date":105,"type":85},"2026-06-30",{"name":5,"class":6},1]