[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563272":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":30,"centralContacts":37,"locations":43,"responsibleParty":60,"collaborators":30,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":30,"eligibilityCriteria":69,"healthyVolunteers":66,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":30,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":45,"whyStopped":30,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Qianfoshan Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group S1","EXPERIMENTAL","Before anesthesia induction, an iliac fascia block was administered using 0.375% ropivacaine (30 mL) under ultrasound guidance, followed by conventional anesthesia induction. During the anesthesia maintenance phase, dexmedetomidine was infused intravenously at a rate of 0.5 µg\u002Fkg\u002Fh.",[13],"Drug: Dexmedetomidine Injection",{"label":15,"type":10,"description":16,"interventionNames":17},"Group S2","Before anesthesia induction, an iliac fascia block was administered using a mixture of 0.375% ropivacaine and 1ug\u002Fkg dexmedetomidine (30ml) under ultrasound guidance. During the anesthesia maintenance phase, an equivalent volume of 0.9% sodium chloride injection was infused intravenously.",[18],"Drug: Ropivacaine and Dexmedetomidine",{"label":20,"type":21,"description":22,"interventionNames":23},"Group C","ACTIVE_COMPARATOR","Before anesthesia induction, an iliac fascia block was performed using 0.375% ropivacaine (30 mL) under ultrasound guidance, followed by conventional anesthesia induction. During the anesthesia maintenance phase, an equivalent volume of 0.9% sodium chloride injection was infused intravenously.",[24],"Drug: Sodium Chloride Injection",[26,31,34],{"type":27,"name":28,"description":11,"armGroupLabels":29,"otherNames":30},"DRUG","Dexmedetomidine Injection",[9],null,{"type":27,"name":32,"description":16,"armGroupLabels":33,"otherNames":30},"Ropivacaine and Dexmedetomidine",[15],{"type":27,"name":35,"description":22,"armGroupLabels":36,"otherNames":30},"Sodium Chloride Injection",[20],[38],{"name":39,"role":40,"phone":41,"phoneExt":30,"email":42},"Pengcai Shi, Chief physician","CONTACT","13791126828","shipc1997@163.com",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Jinan","Shandong","250000","China","CN",{"type":52,"coordinates":53},"Point",[54,55],116.99722,36.66833,{"lat":55,"lon":54},[58],{"name":39,"role":40,"phone":59,"phoneExt":30,"email":42},"86+13791126828",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Pengcai Shi","Chief physician，Master Tutor","100563272","phase-1-effect-of-different-administration-routes-of-dexmedetomidine-combined-with-ultrasound-guided-fascia-iliaca-block-on-emergence-agitation-after-hip-replacement-surgery-100563272",false,"NCT06614010","Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery","Inclusion Criteria:\n\n1. age between 18 and 65 years, with no restriction on gender\n2. diagnosis of hip joint disease necessitating hip arthroplasty\n3. ASA grade I-II\n4. no significant cardiopulmonary, hepatic, or renal dysfunction prior to the operation\n5. no history of psychiatric disorders or long-term use of sedative medications prior to the operation\n6. signing of an informed consent form to voluntarily participate in the study.\n\nExclusion Criteria:\n\n1. patients allergic to or with contraindications to ropivacaine or dexmedetomidine\n2. patients exhibiting symptoms of agitation or delirium prior to the procedure\n3. patients with severe central or peripheral nervous system disorders\n4. patients with coagulation disorders or receiving anticoagulant therapy\n5. pregnant or breastfeeding women\n6. patients who received other medications or treatments prior to the procedure that might affect the study results\n7. patients unable to cooperate with the study or intolerant to ultrasound-guided iliofascial block","ALL","18 Years","65 Years",{"count":74,"type":75},207,"ESTIMATED","INTERVENTIONAL",[78],"PHASE1","To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement surgery.",[81,82],"Dexmedetomidine","Fascia Iliaca Block",[82,81,84,85,86],"Emergence Agitation","Ropivacaine","Analgesic Mechanism","2024-09-23",{"date":89,"type":90},"2024-09-26","ACTUAL",{"date":92,"type":90},"2023-02-05",{"date":94,"type":75},"2025-12-01",{"name":5,"class":6},1]