[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630469":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":31,"responsibleParty":52,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":26,"overallStatus":34,"whyStopped":26,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"King Edward Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Liberal Fluid Administration","ACTIVE_COMPARATOR","1000ml iv fluid",[13],"Drug: Lactated Ringer 1000ml",{"label":15,"type":16,"description":17,"interventionNames":18},"Restricted Fluid Administration","EXPERIMENTAL","500ml iv fluid",[19],"Drug: Lactated Ringer 500ml",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Lactated Ringer 500ml","500ml ringer lactate perioperatively given in laparoscopic cholecystectomy patients as compared to traditional 1000ml fluid",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Lactated Ringer 1000ml","1000ml iv fluid given perioperatively in laparoscopic cholecystectomy",[9],[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"King Edward Medical University Lahore \u002F Mayo Hospital Lahore","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":41,"coordinates":42},"Point",[43,44],74.35071,31.558,{"lat":44,"lon":43},[47],{"name":48,"role":49,"phone":50,"phoneExt":26,"email":51},"Ahmad Uzair Qureshi, FCPS","CONTACT","+923144001410","ahmaduzairq@gmail.com",{"type":53,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100630469","phase-1-effect-of-liberal-and-restrictive-iv-fluids-on-recovery-after-gallbladder-surgery-100630469",false,"NCT07488078","Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery","Effect of Liberal Versus Restrictive Intravenous Fluid Administration on Postoperative Homeostasis in Patients Undergoing Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* All patients undergoing elective cholecystectomy\n* Age : 18-60 years\n* All genders\n* ASA class 1 and 2\n\nExclusion Criteria:\n\n* History of previous laparotomy\n* Perforated gall bladder\n* Duration of surgery more than 3 hours\n* More than 100ml intra operative blood loss","ALL","18 Years","60 Years",{"count":65,"type":66},380,"ESTIMATED","INTERVENTIONAL",[69],"PHASE1","The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy).\n\nThe main questions it aims to answer are:\n\nDoes restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy?\n\nAre there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens?\n\nResearchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes.\n\nParticipants will:\n\nBe adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy.\n\nBe randomly assigned to one of two groups:\n\nGroup A: Liberal IV fluid administration for 6 hours after surgery.\n\nGroup B: Restrictive IV fluid administration for 6 hours after surgery.\n\nHave their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).",[72],"Laparoscopic Cholecystectomy","2026-03-17",{"date":75,"type":76},"2026-03-23","ACTUAL",{"date":78,"type":76},"2025-12-01",{"date":80,"type":66},"2026-07-28",{"name":5,"class":6},1]