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21267579","lana.ufpe@gmail.com",[91],{"facility":5,"status":92,"city":93,"state":94,"zip":11,"country":95,"countryCode":96,"cosmosGeoPoint":97,"geoPoint":102,"contacts":103},"RECRUITING","Recife","Pernambuco","Brazil","BR",{"type":98,"coordinates":99},"Point",[100,101],-34.88111,-8.05389,{"lat":101,"lon":100},[104],{"name":105,"role":87,"phone":88,"phoneExt":11,"email":89},"Monte-Silva",{"type":107,"investigatorFullName":86,"investigatorTitle":108,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Professor","100594923","phase-1-effects-of-peripheral-magnetic-stimulation-on-cortical-excitability-in-healthy-individuals-100594923",false,"NCT07025759","Effects of Peripheral Magnetic Stimulation on Cortical Excitability in Healthy Individuals","Inclusion criteria: Healthy adults aged 18-40 years, both sexes, right-handed (confirmed via Edinburgh Handedness Inventory), and for females, consistent use of contraceptive medication to mitigate hormonal influences on nervous system excitability.\n\nExclusion criteria: Pregnancy; history of seizures or epilepsy; metallic implants in the head, spine, face, or heart; diagnosed neurological or musculoskeletal conditions interfering with assessments or interventions; or use of substances altering nervous system excitability.",true,"ALL","18 Years","40 Years",{"count":120,"type":121},18,"ESTIMATED","INTERVENTIONAL",[124],"PHASE1","This study investigates the immediate effects of different parameters (frequency, intensity, and pulse number) of peripheral magnetic stimulation (rPMS) on cortical excitability in healthy individuals. Using a randomized, double-blind crossover design, the research aims to identify optimal stimulation protocols for modulating neural activity. Outcomes include measurements of motor-evoked potentials (MEPs), intracortical inhibition (ICI), and facilitation (ICF). Findings may enhance non-invasive therapeutic strategies for neurological disorders.",[127],"Healthy Individuals",[129,130],"Peripheral Magnetic Stimulation","Cortical Excitabilty","2025-06-16",{"date":133,"type":134},"2025-06-17","ACTUAL",{"date":136,"type":134},"2022-10-01",{"date":138,"type":121},"2025-10",{"name":5,"class":6},1]