[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622875":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":38,"locations":45,"responsibleParty":64,"collaborators":68,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":29,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":94,"whyStopped":29,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Shaheed Benazir Bhutto University Sheringal Dir Upper","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Rosuvastatin (5mg, 20mg, 40mg)","EXPERIMENTAL","The assigned participants will be given Rosuvastatin 5mg, 20mg, 40mg OD for two days",[13],"Drug: Rosuvastatin (5mg, 20mg, 40mg)",{"label":15,"type":10,"description":16,"interventionNames":17},"Atorvastatin (10mg,20mg, 40mg)","The assigned participants will be given Atorvastatin 10mg,20mg, 40mg OD for two days",[18],"Drug: Atorvastatin (10mg, 20mg, 40mg)",{"label":20,"type":10,"description":21,"interventionNames":22},"Simvastatin (10mg, 20mg, 40mg)","The assigned participants will be given Simvastatin 10mg, 20mg, 40mg OD for two days",[23],"Drug: Simvastatin (10mg, 20mg, 40m",[25,30,34],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"DRUG","The Rosuvastatin (5mg, 20mg, 40mg) group participants will be given the drug orally OD for two days",[9],null,{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Atorvastatin (10mg, 20mg, 40mg)","The Atorvastatin (10mg, 20mg, 40mg) group participants will be given the drug orally OD for two days",[15],{"type":26,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"Simvastatin (10mg, 20mg, 40m","The Simvastatin (10mg, 20mg, 40mg) group participants will be given the drug orally OD for two days",[20],[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Dr Abid Ullah, Ph.D","CONTACT","09448850","527","abid@sbbu.edu.pk",[46],{"facility":5,"status":29,"city":47,"state":48,"zip":29,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Dīr","Khyber Pakhtunkhwa","Pakistan","PK",{"type":52,"coordinates":53},"Point",[54,55],71.8768,35.2074,{"lat":55,"lon":54},[58,61],{"name":59,"role":41,"phone":60,"phoneExt":29,"email":44},"Dr.Abid Ullah, PhD","0944885400",{"name":62,"role":63,"phone":29,"phoneExt":29,"email":29},"Professor Dr. Niaz Ali, PhD","SUB_INVESTIGATOR",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Dr Abid Ullah","Lecturer",[69],{"name":70,"class":6},"Khyber Medical University Peshawar","100622875","phase-1-effects-of-selected-statins-on-cardiovascular-parameters-in-healthy-volunteers-100622875",false,"NCT07389304","[Effects of Selected Statins on Cardiovascular Parameters in Healthy Volunteers]","[EFFECTS OF SELECTED STATINS ON CARDIOVASCULAR PARAMETERS IN HEALTHY VOLUNTEERS: A RANDAMOZIED PHASE I CLINICAL TRIAL]","SBBU\u002FIRC-25-31","Inclusion Criteria:\n\n* Healthy volunteers\n* Normal ECG\n* Normal Blood Pressure\n* Normal lipid levels\n\nExclusion Criteria:\n\n* Participants with a history of diabetes mellitus,BP\n* With chronic diseases e.g heart disease, kidney disease\n* QTc ≥450 ms (men) or ≥470 ms (women)\n* ECG changes\n* Electrolyte imbalance,\n* Participants taking other medications",true,"ALL","18 Years","25 Years",{"count":84,"type":85},100,"ESTIMATED","INTERVENTIONAL",[88],"PHASE1","This study is a Phase I randomized clinical trial aiming to investigate the short-term effects of three commonly prescribed statins i.e (Atorvastatin, Rosuvastatin, and Simvastatin) at different dose levels i.e lo,median and high doses on cardiovascular parameters i.e Blood pressure and ECG morphology in healthy volunteers. The study will assess changes in blood pressure and ECG morphology following two days of statin administration under controlled conditions.",[91],"Lipid Profile,Blood Pressure",[93],"sBlood Pressure,ECG change","NOT_YET_RECRUITING","2026-01-30",{"date":97,"type":98},"2026-02-05","ACTUAL",{"date":100,"type":85},"2026-03-01",{"date":102,"type":85},"2027-02-20",{"name":5,"class":6},1]