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21267579","lana.ufpe@gmail.com",[91],{"facility":5,"status":92,"city":93,"state":94,"zip":95,"country":96,"countryCode":97,"cosmosGeoPoint":98,"geoPoint":103,"contacts":104},"RECRUITING","Recife","Pernambuco","50740-560","Brazil","BR",{"type":99,"coordinates":100},"Point",[101,102],-34.88111,-8.05389,{"lat":102,"lon":101},[105],{"name":106,"role":87,"phone":107,"phoneExt":11,"email":108},"João Fabrício","+55 81 986450112","joaovmelo2015@gmail.com",{"type":110,"investigatorFullName":86,"investigatorTitle":111,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Professor","100595000","phase-1-effects-of-trans-spinal-magnetic-stimulation-on-cortical-excitability-in-healthy-individuals-100595000",false,"NCT07026760","Effects of Trans-spinal Magnetic Stimulation on Cortical Excitability in Healthy Individuals","Healthy adults aged 18-40 years, of both sexes; right-handed (confirmed via the Edinburgh Handedness Inventory); and for women, consistent use of contraceptive medication to mitigate hormonal influences on nervous system excitability.\n\nExclusion Criteria:\n\nPregnancy; history of seizures or epilepsy; metallic implants in the head, spine, face, or heart; diagnosed neurological or musculoskeletal conditions that could interfere with assessments or interventions; or use of substances that alter nervous system excitability.",true,"ALL","18 Years","40 Years",{"count":123,"type":124},18,"ESTIMATED","INTERVENTIONAL",[127],"PHASE1","This study investigates the immediate effects of different parameters (frequency and intensity) of trans-spinal magnetic stimulation (TsMS) on cortical excitability in healthy individuals. Using a randomized, double-blind crossover design, the research aims to identify optimal stimulation protocols for modulating neural activity. Outcomes include measurements of motor-evoked potentials (MEP), intracortical inhibition (ICI), and facilitation (ICF). Findings may enhance non-invasive therapeutic strategies for neurological disorders.",[130],"Healthy Individuals",[132,133],"Trans-spinal magnetic stimulation","Cortical Excitability","2025-06-10",{"date":136,"type":137},"2025-06-18","ACTUAL",{"date":139,"type":137},"2022-10-01",{"date":141,"type":124},"2025-10-30",{"name":5,"class":6},1]