[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634392":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":57,"collaborators":21,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":21,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":21,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":21,"overallStatus":37,"whyStopped":21,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Deciphera Pharmaceuticals, LLC","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Vimseltinib + Combined Oral Contraceptive (COC)","EXPERIMENTAL","Day 1 single dose of combined oral contraceptive (COC) (ethinyl estradiol \\[EE\\]\u002Flevonorgestrel \\[LNG\\]).\n\nDay 4 through 7, Day 11 and Day 14 single daily dose of Vimseltinib. Day 18 coadministration of COC (EE \u002FLNG) with vimseltinib.",[13,14],"Drug: Vimseltinib","Drug: Combined Oral Contraceptive (COC) (ethinyl estradiol [EE]\u002Flevonorgestrel [LNG])",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DRUG","Vimseltinib","Administered orally",[9],null,{"type":17,"name":23,"description":19,"armGroupLabels":24,"otherNames":21},"Combined Oral Contraceptive (COC) (ethinyl estradiol [EE]\u002Flevonorgestrel [LNG])",[9],[26],{"name":27,"affiliation":5,"role":28},"Clinical Team","STUDY_DIRECTOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":21,"email":33},"CONTACT","888-724-3274","clinicaltrials@deciphera.com",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Nucleus Network","RECRUITING","Saint Paul","Minnesota","55114","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-93.09327,44.94441,{"lat":47,"lon":46},[50,54],{"name":51,"role":31,"phone":52,"phoneExt":21,"email":53},"Jennifer Bookey","651-641-2900","j.bookey@nucleusnetwork.com",{"name":55,"role":56,"phone":21,"phoneExt":21,"email":21},"Emmanuel Ferrer, MD","PRINCIPAL_INVESTIGATOR",{"type":58,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100634392","phase-1-evaluate-the-effect-of-vimseltinib-on-pharmacokinetics-of-combined-oral-contraceptive-ethinyl-estradiollevonorgestrel-100634392",false,"NCT07539090","Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol\u002FLevonorgestrel)","A Phase 1, Open-label, Fixed-sequence Study to Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol\u002FLevonorgestrel) in Healthy Female Participants","Inclusion Criteria:\n\n1. Participants are in good general health, as required by the protocol and as determined by Principal Investigator.\n2. Body mass index (BMI) from greater than or equal to (≥) 18.5 to less than or equal to ≤ 30 kilogram per square meter (kg\u002Fm\\^2).\n3. Adequate organ function, blood and urine tests, as required by the protocol and as determined by Principal Investigator.\n\nExclusion Criteria:\n\n1. History or presence of clinically significant diseases of the neurological, dermatological, renal, hepatic, gastrointestinal, cardiovascular, or musculoskeletal systems or history or presence of clinically significant psychiatric, immunological, endocrine, or metabolic disease as determined by Principal Investigator.\n2. Unwilling or unable to comply with the requirements of the protocol.\n3. Determined by Principal Investigator to be unsuitable to participate in the study for any other reason.",true,"FEMALE","18 Years","55 Years",{"count":71,"type":72},24,"ESTIMATED","INTERVENTIONAL",[75],"PHASE1","The main purpose of this study is to determine the effect of vimseltinib on pharmacokinetics of combined oral contraceptive (COC) (ethinyl estradiol\u002Flevonorgestrel) in healthy female participants. This study will last approximately 35 days.",[78],"Healthy Participants","2026-06-15",{"date":81,"type":82},"2026-06-17","ACTUAL",{"date":84,"type":82},"2026-06-05",{"date":86,"type":72},"2026-08",{"name":5,"class":6},1]