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Having clinical diagnosis of primary membranous nephropathy, as verified by biopsy.\n2. Have positive anti-PLA2R autoantibody test results \\> 20 relative units (RU)\u002Fml.\n3. During screening at least one testing of proteinuria must be \\>3.5 g\u002F24h.\n4. Have nephrotic range proteinuria for at least 8 weeks prior to Day 1 and no improvement (\\\u003C50% reduction) despite supportive therapy of ACE inhibitor or ARB unless contraindicated, for patients who have two tests of proteinuria during screening ≥8.0g\u002F24h, the duration of nephrotic range proteinuria for at least 8 weeks is not required.\n\nExclusion Criteria:\n\n1. Non-primary membranous nephropathy or other condition affecting the kidney.\n2. eGFR at screening \\\u003C 45 mL\u002Fmin\u002F1.73m2 or kidney function not stable .\n3. Uncontrolled hypertension .\n4. Serum albumin level at screening # 25g\u002Fl.\n5. Have received: B-cell targeted therapy except rituximab at any time;Rituximab and the biosimilars within 2 years (participants with rituximab treatment between 1 and 2 years prior to Day 1 are eligible if there is documented evidence of B-cell repopulation to \\>90% of Lower Limits of Normal Range.); Cyclophosphamide or Chlorambucil within 180 days;other immunosuppressive\u002Fimmunomodulatory agents within 90 days;greater than 30mg\u002Fday prednisone or equivalence within 30 days.\n6. Acute or chronic infection,including positivity of tuberculosis infection test.\n7. Positive serology for TP,HIV, HBV, or HCV.\n8. Lab testing abnormality as: WBC\\\u003C 3000\u002Fmm³, Lymphocyte \\\u003C 1000\u002F mm³, neutrophil \\\u003C1500\u002Fmm³, Hb \\\u003C 80g\u002FL, Platelet count \\\u003C100×10e9\u002F L, Prothrombin time\\>1.5×ULN, Activated partial thromboplastin time ≥1.5×ULN, Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≥ 1.5×ULN, alkaline phosphatase and bilirubin \\>1.5×ULN.\n9. 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