[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522693":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":29,"responsibleParty":58,"collaborators":19,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":19,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":19,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":19,"overallStatus":50,"whyStopped":19,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Ketamine","EXPERIMENTAL","All patients will receive the experimental drug.",[13],"Drug: Ketamine",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DRUG","Patients will receive 0.2mg\u002Fkg of IV ketamine",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Lindsay Maguire, MD","CONTACT","913-588-3580","lmaguire@kumc.edu",{"name":27,"role":23,"phone":19,"phoneExt":19,"email":28},"Lucas Lemar","llemar@kumc.edu",[30,48],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"University of Kansas Strawberry Hill Campus","NOT_YET_RECRUITING","Kansas City","Kansas","66101","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-94.62746,39.11417,{"lat":42,"lon":41},[45],{"name":46,"role":23,"phone":19,"phoneExt":19,"email":47},"Tyler Kjorvestad, MD","tkjorvestad@kumc.edu",{"facility":49,"status":50,"city":33,"state":34,"zip":51,"country":36,"countryCode":37,"cosmosGeoPoint":52,"geoPoint":54,"contacts":55},"University of Kansas Medical Center Emergency Department","RECRUITING","66160",{"type":39,"coordinates":53},[41,42],{"lat":42,"lon":41},[56],{"name":22,"role":23,"phone":57,"phoneExt":19,"email":25},"8048144509",{"type":59,"investigatorFullName":22,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"SPONSOR_INVESTIGATOR","Assistant Professor of Emergency Medicine","100522693","phase-1-feasibility-and-safety-of-ketamine-for-suicidal-patients-in-the-emergency-department-100522693",false,"NCT06085937","Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department","Feasibility and Safety of Single Dose Ketamine for Acutely Suicidal Patients in the Emergency Department","Inclusion Criteria:\n\n* Acutely Suicidality (\"yes\" answer to any of items 4 or 5 on C-SSRS \"Suicidal Ideation\" category)\n* Require inpatient stabilization for SI or actions based on clinical observation and interview\n* Are accepted for psychiatric stabilization at the University of Kansas Medical Center's Strawberry Hill campus\n* Have a Glasgow Coma Score (GCS) of 15\n* Age 18-65\n\nExclusion Criteria:\n\n* Current or past history of psychosis\n* Current or recent (past 4 weeks) symptoms of mania\u002Fhypomania as defined by Young Mania Rating Scale (YRMS) score of 12 or greater\n* History of ketamine use disorder\n* History of liver transplant\n* Pregnancy or breastfeeding\n* Imprisonment or inability to consent\n* Positive urine drug screen or serum alcohol level\n* Hypertension (SBP \\> 160 or DBP \\> 100 before administration of ketamine)\n* Hypotension (SBP \\\u003C 90)\n* Presence of acute medical condition requiring admission to medical service\n* Allergy, intolerance, or previous adverse reaction to ketamine\n* Patient has 8+ lifetime ketamine exposures\n* The treating physician determines that the patient is not a good candidate for the study (e.g. medical condition\u002Fprocedure, medication that would contradindicate ketamine treatment)","ALL","18 Years","65 Years",{"count":72,"type":73},50,"ESTIMATED","INTERVENTIONAL",[76],"PHASE1","There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.",[79,80,81],"Suicide","Suicidal Ideation","Depression","2026-04-12",{"date":84,"type":85},"2026-04-15","ACTUAL",{"date":87,"type":85},"2024-05-01",{"date":89,"type":73},"2027-04",{"name":22,"class":6},2]