[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636784":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":24,"locations":25,"responsibleParty":36,"collaborators":24,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":24,"eligibilityCriteria":44,"healthyVolunteers":45,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":24,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":62,"whyStopped":24,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Onconic Therapeutics Inc.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Korean\u002FCaucasian Participants: JPI-547 Fed\u002FFasted Crossover","EXPERIMENTAL","Healthy Korean and Caucasian male participants receive a single oral dose of JPI-547 in each treatment period under fed and fasted conditions in a crossover design.",[13],"Drug: JPI-547",{"label":15,"type":10,"description":16,"interventionNames":17},"Chinese Participants: JPI-547 Fasted","Healthy Chinese male participants receive a single oral dose of JPI-547 under fasting conditions.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","JPI-547","JPI-547 is administered orally as a single dose per administration.",[15,9],null,[26],{"facility":27,"status":24,"city":28,"state":24,"zip":24,"country":29,"countryCode":24,"cosmosGeoPoint":30,"geoPoint":35,"contacts":24},"Seoul National University Hospital","Seoul","South Korea",{"type":31,"coordinates":32},"Point",[33,34],126.9784,37.566,{"lat":34,"lon":33},{"type":37,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100636784","phase-1-food-and-ethnicity-effects-on-pharmacokinetics-and-safety-of-jpi-547-in-healthy-male-participants-100636784",false,"NCT07570186","Food and Ethnicity Effects on Pharmacokinetics and Safety of JPI-547 in Healthy Male Participants","A Randomized, Open-label, Single-dose, Crossover Phase 1 Clinical Trial to Evaluate the Effects of Food or Ethnicity on the Pharmacokinetics and Safety\u002FTolerability of JPI-547 After a Single Oral Administration in Healthy Male Korean, Caucasian and Chinese Participants","Inclusion Criteria:\n\n* Healthy Korean, Caucasian, or Chinese male participants aged 19 to 50 years at screening\n* Body weight between 50.0 and 90.0 kg and BMI between 18.5 and 29.9 kg\u002Fm²\n* Able to understand the study and provide written informed consent\n* Considered suitable for study participation by the investigator based on medical history, physical examination, and clinical laboratory tests\n\nExclusion Criteria:\n\n* Clinically significant medical or surgical history\n* Gastrointestinal disease or surgery affecting drug absorption\n* Hypersensitivity to PARP inhibitors or other significant drug allergy\n* Drug abuse history or positive drug screening\n* Clinically significant abnormal vital signs or laboratory results\n* Positive viral or serologic screening tests\n* Recent use of prohibited medications\n* Recent participation in another clinical trial\n* Recent blood donation or transfusion\n* Inability to abstain from smoking, alcohol, caffeine, or grapefruit\n* Failure to comply with contraception or sperm donation requirements\n* Any condition making the participant unsuitable in the investigator's judgment",true,"MALE","19 Years","50 Years",{"count":50,"type":51},36,"ESTIMATED","INTERVENTIONAL",[54],"PHASE1","This study aims to evaluate the effects of food or ethnicity on the pharmacokinetics and safety\u002Ftolerability of JPI-547 after a single oral administration in healthy male Korean, Caucasian, and Chinese participants.",[57],"Healthy Volunteers",[21,59,60,61],"Food Effect","Ethnicity","Pharmacokinetics","NOT_YET_RECRUITING","2026-04-29",{"date":65,"type":66},"2026-05-06","ACTUAL",{"date":68,"type":51},"2026-05",{"date":70,"type":51},"2026-07",{"name":5,"class":6},1]