[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100269022":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":31,"locations":38,"responsibleParty":55,"collaborators":30,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":30,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":30,"overallStatus":41,"whyStopped":30,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"THC","ACTIVE_COMPARATOR","Active THC (0.015mg\u002Fkg) administered intravenously over 10 minutes.",[13],"Drug: THC",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Control: small amount of alcohol intravenously (quarter teaspoon), with no THC over 10 minutes.",[19],"Drug: Placebo",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Active THC (0.015mg\u002Fkg) administered over 10 minutes",[9],[26],"Delta-9-Tetrahydrocannabinol",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"Control: small amount of alcohol (quarter teaspoon), with no THC over 10 minutes",[15],null,[32],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Christina Luddy, BS","CONTACT","203-932-5711","4549","christina.luddy@yale.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine","RECRUITING","West Haven","Connecticut","06516","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-72.94705,41.27065,{"lat":51,"lon":50},[54],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Mohini Ranganathan","Assistant Professor of Psychiatry","100269022","phase-1-gender-related-differences-in-the-acute-effects-of-delta-9-tetrahydrocannabinol-in-healthy-humans-100269022",false,"NCT02781519","Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans","THC-Gender","Inclusion Criteria:\n\n* at least one lifetime exposure to cannabis\n* good physical and mental health\n\nExclusion Criteria:\n\n* cannabis naive individuals\n* major current or recent stressors\n* taking estrogen supplements or oral contraceptive pills (for women)",true,"ALL","18 Years","55 Years",{"count":71,"type":72},100,"ESTIMATED","INTERVENTIONAL",[75],"PHASE1","The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.",[78],"Cannabis","2025-06-05",{"date":81,"type":82},"2025-06-10","ACTUAL",{"date":84,"type":30},"2015-06",{"date":86,"type":72},"2026-12",{"name":5,"class":6},1]