[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100448617":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":29,"centralContacts":33,"locations":43,"responsibleParty":60,"collaborators":37,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":37,"eligibilityCriteria":67,"healthyVolunteers":64,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":37,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":37,"overallStatus":45,"whyStopped":37,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"68Ga-FAPI-04 PET\u002FCT and 18F-FDG PET\u002FCT","EXPERIMENTAL","All patients diagnosed with Lung fibrosis underwent 68Ga-FAPI PET\u002FCT and 18F-FDG PET\u002FCT.",[13,14],"Drug: 68Ga-FAPI","Drug: 18F-FDG",[16,23],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DRUG","68Ga-FAPI","Intravenous injection of one dosage of 18.5-22.2MBq (0.5-0.6 mCi)\u002FKg 68Ga-FAPI. Tracer doses of 68Ga-FAPI will be used to image lesions of pulmonary fibrosis by PET\u002FCT.",[9],[22],"68Ga-fibroblast activating protein inhibitors",{"type":17,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"18F-FDG","Intravenous injection of one dosage of 4.44-5.55 MBq(0.12-0.15mCi)\u002FKg 18F-FDG. Tracer doses of 18F-FDG will be used to image lesions of pulmonary fibrosis by PET\u002FCT.",[9],[28],"18F-Fluorodeoxyglucose",[30],{"name":31,"affiliation":5,"role":32},"Zhaohui Zhu, MD","PRINCIPAL_INVESTIGATOR",[34,39],{"name":31,"role":35,"phone":36,"phoneExt":37,"email":38},"CONTACT","86-13611093752",null,"13611093752@163.com",{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},"Jiarou Wang, MS","86-13628477019","pumc_wangjiarou@student.pumc.edu.cn",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Beijing","Beijing Municipality","100730","China","CN",{"type":52,"coordinates":53},"Point",[54,55],116.39723,39.9075,{"lat":55,"lon":54},[58,59],{"name":31,"role":35,"phone":36,"phoneExt":37,"email":38},{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},{"type":61,"investigatorFullName":37,"investigatorTitle":37,"investigatorAffiliation":37,"oldNameTitle":37,"oldOrganization":37},"SPONSOR","100448617","phase-1-head-to-head-comparison-of-diagnosis-value-of-pulmonary-fibrosis-on-68ga-fapi-04-and-18f-fdg-pet-ct-100448617",false,"NCT05121779","Head-to-head Comparison of Diagnosis Value of Pulmonary Fibrosis on 68Ga-FAPI-04 and 18F-FDG PET-CT","Inclusion Criteria:\n\n* suspected or confirmed pulmonary fibrosis patients;\n* signed written consent.\n\nExclusion Criteria:\n\n* pregnancy;\n* breastfeeding;\n* known allergy against FAPI\n* any medical condition that in the opinion of the investigator may significantly interfere with study compliance","ALL","18 Years","80 Years",{"count":72,"type":73},80,"ESTIMATED","INTERVENTIONAL",[76],"PHASE1","68Ga-fibroblast activating protein inhibitors(FAPI) has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation,such as inflammatory bowel disease. And it might be more sensitive than FDG in detecting a certain type of inflammations according to our preliminary research. Thus this prospective study is going to investigate whether 68Ga-FAPI PET\u002FCT may be superior for diagnosis, therapy response assessment and follow-up of Pulmonary fibrosis than 18F-FDG PET\u002FCT.",[79],"Pulmonary Fibrosis","2024-11-21",{"date":82,"type":83},"2024-11-25","ACTUAL",{"date":85,"type":83},"2021-11-18",{"date":87,"type":73},"2025-12-31",{"name":5,"class":6},1]