[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582162":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":41,"locations":51,"responsibleParty":68,"collaborators":72,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":40,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":98,"overallStatus":54,"whyStopped":40,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo Comparator: Placebo","PLACEBO_COMPARATOR","0 mg THC",[13],"Drug: Placebo Comparator: Placebo",{"label":15,"type":16,"description":17,"interventionNames":18},"Low dose THC","ACTIVE_COMPARATOR","50 mg THC",[19],"Drug: Low dose THC",{"label":21,"type":16,"description":22,"interventionNames":23},"High dose THC","100 mg THC",[24],"Drug: High dose THC",[26,32,36],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","Placebo",[9],[31],"Cannabis",{"type":27,"name":15,"description":33,"armGroupLabels":34,"otherNames":35},"Smoked low dose THC",[15],[31],{"type":27,"name":21,"description":37,"armGroupLabels":38,"otherNames":39},"Smoked high dose THC",[21],[31],null,[42,47],{"name":43,"role":44,"phone":45,"phoneExt":40,"email":46},"Ziva Cooper, PhD","CONTACT","310-206-9942","cannabislab@mednet.ucla.edu",{"name":48,"role":44,"phone":49,"phoneExt":40,"email":50},"Vincent Acebo","310-983-3417","vacebo@mednet.ucla.edu",[52],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"UCLA Center for Cannabis and Cannabinoids","RECRUITING","Los Angeles","California","90095","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-118.24368,34.05223,{"lat":64,"lon":63},[67],{"name":48,"role":44,"phone":49,"phoneExt":40,"email":50},{"type":69,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"PRINCIPAL_INVESTIGATOR","Ziva D. Cooper, PhD","Professor",[73],{"name":74,"class":75},"California Department of Cannabis Control (DCC)","UNKNOWN","100582162","phase-1-high-potency-cannabis-acute-and-protracted-effects-100582162",false,"NCT06859723","High Potency Cannabis: Acute and Protracted Effects","HIGH-CAP","Inclusion Criteria:\n\n* • Male or non-pregnant and non-lactating females aged 21-55 years\n\n  * Report cannabis smoking near daily\n  * Not currently seeking treatment for their cannabis use\n  * Have a Body Mass Index from 18.5 - 34kg\u002Fm2.\n  * Able to perform all study procedures\n  * Must be using a contraceptive (hormonal or barrier methods)\n\nExclusion Criteria:\n\n* Meeting DSM-V criteria for any substance use disorder other than cannabis, nicotine, caffeine\n* Do not have positive urine toxicology for cannabis use during screening\n* Evidence of severe psychiatric illness (e.g. mood or anxiety disorder with functional impairment or suicide risk, schizophrenia) judged by the study physician (and PI) to put the participant at greater risk of experiencing adverse events due to completion of study procedures, interfere with their ability to participate in the study, or their capacity to provide informed consent.\n* Report using other illicit drugs in the prior 4 weeks\n* Current predominant licit use of medical cannabis, prescription analgesics, or any medications that may affect study outcomes\n* Current pain\n* Pregnancy\n* Currently enrolled in another research protocol\n* Not using a contraceptive method (hormonal or barrier methods)\n* Insensitivity to the cold water stimulus of the Cold Pressor Test\n* Any disorders that might make cannabis administration hazardous as determined by evaluation physician after review of all medical assessments along with medical history.\n* Not able to speak and read English",true,"ALL","21 Years","55 Years",{"count":88,"type":89},30,"ESTIMATED","INTERVENTIONAL",[92],"PHASE1","The purpose of this research is to assess the effects of smoked cananbis when cannabis is smoked during periods of cannabis use as usual and after a brief period of abstinence.",[95,96,97],"Abuse Cannabis","Pain","Pharmacokinetics",[99,31],"THC","2025-09-30",{"date":102,"type":103},"2025-10-06","ACTUAL",{"date":105,"type":103},"2025-07-03",{"date":107,"type":89},"2028-07-01",{"name":5,"class":6},1]