[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616138":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":33,"locations":43,"responsibleParty":66,"collaborators":11,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":11,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":11,"studyType":81,"phases":82,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":46,"whyStopped":11,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Uniformed Services University of the Health Sciences","FED",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Myofunctional Therapy","EXPERIMENTAL",null,[13],"Behavioral: High-Resistance Breathing and Drinking Exercises",{"label":15,"type":16,"description":11,"interventionNames":17},"Relaxation Therapy","SHAM_COMPARATOR",[18],"Behavioral: Low-Resistance Breathing and Drinking Exercises",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","High-Resistance Breathing and Drinking Exercises","Three months of drinking at least 32-oz of water daily through a high-resistance nozzle, and inhaling and exhaling 60 times per day through a high-resistance breathing device",[9],[26],"Device-Assisted Myofunctional Therapy",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Low-Resistance Breathing and Drinking Exercises","Three months of drinking 32-oz of water daily through a low-resistance nozzle, and inhaling and exhaling 40 times per day through a low-resistance breathing device",[15],[32],"Placebo Therapy",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Nancy P. Solomon, Ph.D.","CONTACT","301-319-7042","nancy.p.solomon.civ@health.mil",{"name":40,"role":36,"phone":11,"phoneExt":41,"email":42},"Kathleen M. Moran, Ed.D","443-776-1689","kmoran@genevausa.org",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Walter Reed National Military Medical Center","RECRUITING","Bethesda","Maryland","20889","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-77.10026,38.98067,{"lat":56,"lon":55},[59,62,64],{"name":60,"role":36,"phone":61,"phoneExt":41,"email":42},"Kathleen M. Moran, Ed.D.","574-344-8933",{"name":35,"role":63,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"name":65,"role":63,"phone":11,"phoneExt":11,"email":11},"Kent Werner, MD, PhD",{"type":67,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100616138","phase-1-low-tech-treatments-for-obstructive-sleep-apnea-100616138",false,"NCT07301710","Low-Tech Treatments for Obstructive Sleep Apnea","Myofunctional Therapy for Obstructive Sleep Apnea in U.S. Service Members With and Without Traumatic Brain Injury","Inclusion Criteria:\n\n* New diagnosis of OSA (AHI, ≥ 5) or failure of first-line OSA treatment;\n* Willingness to forego first-line OSA treatment or stop current OSA treatment for 3 months;\n* Ability to follow directions and perform the required exercises;\n* Age between 18-65 yr.\n\nExclusion Criteria:\n\n* Current use of OSA treatment;\n* Medical comorbidities that require restricting fluid intake (e.g., dysphagia, renal disease, liver disease, hyponatremia);\n* Severe nasal obstruction; 4) severe ankyloglossia; 4) craniofacial abnormality; 5) severe pulmonary disease; 6) severe post-traumatic stress disorder; 7) very severe insomnia; 8) body mass index (BMI) ≥30 kg\u002Fm2","ALL","18 Years","65 Years",{"count":79,"type":80},60,"ESTIMATED","INTERVENTIONAL",[83,84],"PHASE1","PHASE2","The overall purpose of this study is to compare changes in sleep outcomes in people with obstructive sleep apnea (OSA) depending on their participation in one of two behavioral interventions; both involve drinking water and breathing. A second purpose is to compare outcomes between people who have sustained a traumatic brain injury (TBI) and those with no history of TBI. The main questions it aims to answer are whether sleep quality improves after 3-months of high-resistance versus low-resistance exercises, and whether people have different outcomes depending on their history of TBI.",[87,88],"Obstructive Sleep Apnea (OSA)","Traumatic Brain Injury (TBI)",[90,9,91,92,93,94],"Obstructive Sleep Apnea","Traumatic Brain Injury","Randomized Controlled Trial","Oropharyngeal Exercises","Respiratory Resistance Training","2026-02-11",{"date":97,"type":98},"2026-02-17","ACTUAL",{"date":100,"type":98},"2026-01-29",{"date":102,"type":80},"2027-12",{"name":5,"class":6},1]