[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511417":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":42,"locations":51,"responsibleParty":96,"collaborators":98,"id":104,"slug":105,"hasResults":106,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":23,"eligibilityCriteria":110,"healthyVolunteers":106,"sex":111,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":23,"studyType":117,"phases":118,"briefSummary":121,"conditions":122,"keywords":23,"overallStatus":53,"whyStopped":23,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Cell Energy Life Sciences Group Co. LTD","INDUSTRY",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"placebo control","PLACEBO_COMPARATOR","use saline",[13],"Other: saline",{"label":15,"type":16,"description":17,"interventionNames":18},"mesenchymal stem cells standard treatment","EXPERIMENTAL","transplant mesenchymal stem cells for 3 times",[19],"Drug: mesenchymal stem cell",{"label":21,"type":16,"description":22,"interventionNames":23},"mesenchymal stem cells enhanced treatment","transplant mesenchymal stem cells for 6 times",null,[25,32],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","mesenchymal stem cell","Mesenchymal stem cell dose is 0.75-1.0×10\\*6\u002Fkg and is transplanted by intravenous infusion. For the mesenchymal stem cell standard treatment group, the cells are used for three times(at week 0, 2,4 after recruitment) and the mesenchymal stem cell enhanced treatment group, the cells are used for six times(at week 0, 2,4,24,26,28 after recruitment).",[15],[31],"umbilical cord derived MSCs",{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":23},"OTHER","saline","saline is used as placebo in the placebo comparator group",[9],[38],{"name":39,"affiliation":40,"role":41},"Fu-Sheng Wang, Doctor","Beijing 302 Hospital","PRINCIPAL_INVESTIGATOR",[43,47],{"name":39,"role":44,"phone":45,"phoneExt":23,"email":46},"CONTACT","8610-13671005510","fswang302@163.com",{"name":48,"role":44,"phone":49,"phoneExt":23,"email":50},"Robert Chunhua Zhao, Doctor","8610-13701289612","zhaochunhua@vip.163.com",[52,66,74,85],{"facility":40,"status":53,"city":54,"state":23,"zip":23,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"RECRUITING","Beijing","China","CN",{"type":58,"coordinates":59},"Point",[60,61],116.39723,39.9075,{"lat":61,"lon":60},[64,65],{"name":39,"role":44,"phone":45,"phoneExt":23,"email":46},{"name":39,"role":41,"phone":23,"phoneExt":23,"email":23},{"facility":67,"status":53,"city":54,"state":23,"zip":23,"country":55,"countryCode":56,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Beijing YouAn Hospital",{"type":58,"coordinates":69},[60,61],{"lat":61,"lon":60},[72],{"name":73,"role":44,"phone":23,"phoneExt":23,"email":23},"Li-Jun Sun, Doctor",{"facility":75,"status":53,"city":76,"state":23,"zip":23,"country":55,"countryCode":56,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Shenzhen Third People's Hospital","Shenzhen",{"type":58,"coordinates":78},[79,80],114.0683,22.54554,{"lat":80,"lon":79},[83],{"name":84,"role":44,"phone":23,"phoneExt":23,"email":23},"Fu-Xiang Wang, Doctor",{"facility":86,"status":53,"city":87,"state":23,"zip":23,"country":55,"countryCode":56,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"The Fifth Hospital of Shijiazhuang","Shijiazhuang",{"type":58,"coordinates":89},[90,91],114.47861,38.04139,{"lat":91,"lon":90},[94],{"name":95,"role":44,"phone":23,"phoneExt":23,"email":23},"Er-Hei Dai, Doctor",{"type":97,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[99,100,101,103],{"name":40,"class":33},{"name":75,"class":33},{"name":102,"class":33},"Fifth Hospital of Shijiazhuang City",{"name":67,"class":33},"100511417","phase-1-mesenchymal-stem-cells-treatment-for-aids-patients-at-late-stage-100511417",false,"NCT05939167","Mesenchymal Stem Cells Treatment for AIDS Patients at Late Stage","A Double-blind, Randomized Placebo-controlled Clinical Trial to Investigate the Safety and Efficacy of Mesenchymal Stem Cells Treatment for AIDS Patients at Late Stage","Inclusion Criteria:\n\n1. Confirmed HIV infection, aged 18-65, both genders\n2. CD4+T count less than 500 cells\u002Ful at baseline.\n3. No serious AIDS related events. 3. could understand and sign the informed consent form and comply with the requirements of this study.\n\n4\\. agree not to participate in other studies and not to receive other immunotherapies during the period of participation in this study\n\nExclusion Criteria:\n\n1. have HBV\u002FHCV\u002FHDV\u002FHEV infection, and the virological test is positive.\n2. The viral load for CMV and EBV is more than 1000 copies\u002FML.\n3. have HIV-2 infection.\n4. have serious complications in organs including renal, circulatory, respiratory, digestive, endocrine, neural and immunological diseases and tumors.\n5. received treatment of hormones or other immunosuppressive drugs for a long time.\n6. with serious AIDS related or unrelated events.\n7. received immunosuppressive drugs or systemic cytotoxic drugs for more than 3 months before recruiting\n8. have poor compliance during treatment.\n9. drug addiction within 6 months, or the urine drug test is positive\n10. participate in other clinical trials currently\n11. pregnant, breastfeeding, or have fertility requirements.\n12. unable or unwilling to provide informed consents, or unable to comply with research requirements.\n13. Other serious situations that may hinder clinical trials.","ALL","18 Years","65 Years",{"count":115,"type":116},150,"ESTIMATED","INTERVENTIONAL",[119,120],"PHASE1","PHASE2","The goal of this study is to conduct a prospective, double-blind, randomized placebo-controlled clinical trial to investigate the safety and efficacy of mesenchymal stem cells treatment for AIDS patients at late stage.",[123],"AIDS","2025-08-07",{"date":126,"type":127},"2025-08-12","ACTUAL",{"date":129,"type":127},"2023-12-10",{"date":131,"type":116},"2028-07-10",{"name":5,"class":6},4]