[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556029":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":50,"collaborators":25,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Collagen sponge group :","SHAM_COMPARATOR","ten sites will be treated by MPI technique+ cortical lamina membrane and collagen sponge.\n\nThe jumping gap between implant and buccal plate of bone will be filled with collagen sponge.",[13],"Procedure: Modified periosteal inhibition",{"label":15,"type":16,"description":17,"interventionNames":18},"Bone graft group:","ACTIVE_COMPARATOR","ten sites will be treated by MPI technique +cortical lamina membrane and xenograft collagen.\n\nThe jumping gap between implant and buccal plate of bone will be filled with xenograft collagen.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Modified periosteal inhibition","After local anathesia, a traumatic extraction of the hopeless tooth will be made trying as much as possible to preserve the labial plate of bone and overlying soft tissue.\n\n* Once the tooth is extracted, the socket is gently debrided and irrigated using sterile saline solution. Then the dental implant is placed in the best prosthetic driven position, following the guidelines for immediate implants using prefabricated computer guided surgical template.\n* After accurate implant placement, a full-thickness flap will be elevated at mesial and distal papilla making a buccal envelope. A soft bone lamina will be trimmed and hydrated in sterile saline solution for 30 s to soften it; it should be 1-2 mm larger and deeper than the vestibular bone. Then the jumping gap between the dental implant and the buccal plate of bone will be filled using either collagen sponge or xenograft.",[15,9],null,[27],{"name":28,"affiliation":5,"role":29},"Ghadeer Elbagoory, Msc","STUDY_CHAIR",[31],{"name":28,"role":32,"phone":33,"phoneExt":34,"email":35},"CONTACT","00201118851277","Tanta","ghadeer_elbagoory@dent.tanta.edu.eg",[37],{"facility":38,"status":39,"city":34,"state":25,"zip":25,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"ElGharbiya","RECRUITING","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.00192,30.78847,{"lat":46,"lon":45},[49],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":35},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ghadeer Khalil Elbagoory","Associate lecturer","100556029","phase-1-modified-periosteal-inhibition-with-simultaneous-implant-placement-in-aesthetic-zone-100556029",false,"NCT06519773","Modified Periosteal Inhibition with Simultaneous Implant Placement in Aesthetic Zone","Modified Periosteal Inhibition Utilizing Bone Graft Versus Collagen Sponge with Simultaneous Implant Placement in Aesthetic Zone","Inclusion Criteria:\n\n1. Intact labial plate of bone with thickness ≤1 mm (Socket type I).\n2. Moderate to thick gingival phenotype.\n3. Bone quality ranges from D2-D3 as gained from preoperative cone beam computed tomography.\n4. Presence of at least 3 mm of keratinized gingiva.\n5. Optimal compliance as evidenced by no missing treatment appointments and positive attitude towards oral hygiene.\n\nExclusion Criteria:\n\n1. Medically compromised patients and systemic conditions precluding implant and periodontal surgery.\n2. Pregnant or lactating women.\n3. Smoking\n4. Absence of buccal plate of bone.\n5. History of chemotherapy, radiotherapy in head and\u002For neck region.\n6. Bisphosphonate therapy.",true,"ALL","18 Years","60 Years",{"count":66,"type":67},20,"ESTIMATED","INTERVENTIONAL",[70,71],"PHASE1","PHASE2","A randomized controlled clinical and radiographic trial. Twenty sites with remaining roots or non-restorable teeth in the maxillary anterior region that fulfill the inclusion criteria will be selected from the Periodontology Clinic, Faculty of Dentistry, Tanta University. These sites will be divided into two groups; each of which has ten surgical sites. After phase I therapy, a traumatic extraction of the hopeless tooth will be made trying as much as possible to preserve the labial plate of bone and overlying soft tissue.\n\n* Once the tooth is extracted, the socket is gently debrided and irrigated using sterile saline solution. Then the dental implant is placed in the best prosthetic driven position, following the guidelines for immediate implants using prefabricated computer guided surgical template.\n* After accurate implant placement, a full-thickness flap will be elevated at mesial and distal papilla making a buccal envelope. A bone lamina 0.5 mm thickness will be trimmed and hydrated in sterile saline solution for 30 s to soften it; it should be 1-2 mm larger and deeper than the vestibular bone.",[74],"Immediate Dental Implant",[76,22],"Immediate implant","2025-03-21",{"date":79,"type":80},"2025-03-26","ACTUAL",{"date":82,"type":80},"2024-07-01",{"date":84,"type":67},"2025-10-01",{"name":5,"class":6},1]