[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562129":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":24,"responsibleParty":39,"collaborators":24,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":24,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":24,"enrollmentInfo":51,"targetDuration":24,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":66,"whyStopped":24,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":24},{"fullName":5,"class":6},"Stanford University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pain Patients With Spinal or Peripheral Nerve Origin","EXPERIMENTAL","Individuals suffering from nerve pain that is of spinal or peripheral nerve origin and undergo a \\[18F\\]FTC-146 PET\u002FMRI scan.",[13],"Drug: [18F]FTC-146",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Volunteers","Individuals who do not have pain and undergo a \\[18F\\]FTC-146 PET\u002FMRI scan.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","[18F]FTC-146","Adult participants will be injected with 5-10 mCi of \\[18F\\]FTC-146 and undergo a PET\u002FMRI scan.",[15,9],null,[26],{"name":27,"affiliation":28,"role":29},"Anand Veeravagu","Stanford University- Neurosurgery","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"Adrian Valladarez","CONTACT","(650) 381-4257","adrian98@stanford.edu",{"name":37,"role":33,"phone":24,"phoneExt":24,"email":38},"Neurosurgery Research Team","neurosurgeryresearch@stanford.edu",{"type":29,"investigatorFullName":27,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"M.D. Asst. Professor","100562129","phase-1-petmri-for-chronic-pain-from-spinal-or-peripheral-nerve-origin-100562129",false,"NCT06599151","PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin","Use of (18F)FTC-146 PET_MRI for Characterizing Chronic Pain Phenotypes in Chronic Pain Patients with Spinal or Peripheral Nerve Origin","Inclusion Criteria:\n\n* Healthy Volunteers\n\n  1\\. At least 18 years old.\n* Pain Subjects\n\n  1. At least 18 years old.\n  2. Chronic Pain is of Spinal or Peripheral Nerve Origin\n  3. Subject's Chronic pain lasting greater than 2 months.\n  4. Pain level of at least 4\u002F10 on a 0-10 Comparative Pain Scale.\n\nExclusion Criteria:\n\n* Healthy Volunteers\n\n  1. Any chronic Pain\n  2. Use of pain medication.\n  3. MRI incompatibility.\n  4. Kidney problems.\n  5. Pregnant or nursing.\n  6. Non-English speaker.\n  7. Presence of vasculopathy or Raynaud's.\n  8. Inability to tolerate cessation of anticoagulant medication during the study.\n* Pain Subjects\n\n  1. MRI incompatibility.\n  2. Kidney problems.\n  3. Pregnant or nursing.\n  4. Non-English speaker.",true,"ALL","18 Years",{"count":52,"type":53},200,"ESTIMATED","INTERVENTIONAL",[56],"PHASE1","The purpose of this study is to compare the uptake of \\[18F\\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin.\n\nPrimary Objectives:\n\nA) To quantify the bio-distribution of \\[18F\\] FTC-146 uptake in subjects with Spinal or Peripheral Nerve Origin pain and compare it with healthy controls.\n\nB) To determine whether painful schwannomas can be differentiated from non-painful schwannomas based on imaging.\n\nSecondary Objectives:\n\nA) To assess the reproducibility of \\[18F\\]FTC-146 PET imaging within the same healthy volunteer subjects using Test-Retest analysis.\n\nB) To investigate whether post-treatment \\[18F\\]FTC-146 uptake differs from pre-treatment uptake and correlate the imaging with subject reported pain level after treatment",[59,60,61,62],"Nerve Pain","Neuropathic Pain","Nociceptive Pain","MIxed Pain (Nociceptive and Neuropathic)",[64,65,59],"PET\u002FMRI","Chronic Pain","NOT_YET_RECRUITING","2024-09-12",{"date":69,"type":70},"2024-09-19","ACTUAL",{"date":72,"type":53},"2024-10-01",{"date":74,"type":53},"2030-10-01",{"name":5,"class":6}]