[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100450966":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":20,"locations":25,"responsibleParty":44,"collaborators":20,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":20,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":20,"maxAge":20,"enrollmentInfo":54,"targetDuration":20,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":28,"whyStopped":20,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"The Foundation for Orthopaedics and Regenerative Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment Group (AlloEx)","EXPERIMENTAL","Intranasal installation of 4 CCs of AlloEx, which is approximately 800 billion exosomes.",[13],"Biological: AlloEx",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BIOLOGICAL","AlloEx","cultured allogeneic adult umbilical cord derived mesenchymal stem cell exosomes",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Chadwick Prodromos, MD","PRINCIPAL_INVESTIGATOR",[26],{"facility":27,"status":28,"city":29,"state":20,"zip":20,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Medical Surgical Associates Center","RECRUITING","St John's","Antigua and Barbuda","AG",{"type":33,"coordinates":34},"Point",[35,36],-61.84329,17.12096,{"lat":36,"lon":35},[39],{"name":40,"role":41,"phone":42,"phoneExt":20,"email":43},"Chadwick Prodromos, M.D.","CONTACT","8476996810","care@thepsci.com",{"type":45,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100450966","phase-1-safety-of-cultured-allogeneic-adult-umbilical-cord-stem-cells-exosomes-for-trigeminal-neuralgia-100450966",false,"NCT05152368","Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells Exosomes for Trigeminal Neuralgia","Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells Exosomes for the Treatment of Trigeminal Neuralgia","Inclusion Criteria:\n\n* Diagnosis of Trigeminal Neuralgia or Peripheral Neuropathy\n* Understanding and willingness to sign a written informed consent document\n\nExclusion Criteria:\n\n* Active infection\n* Active cancer\n* Chronic multisystem organ failure\n* Pregnancy\n* Clinically significant Abnormalities on pre-treatment laboratory evaluation\n* Medical condition that would (based on the opinion of the investigator) compromise patient's safety.\n* Continued drug abuse\n* Pre-menopausal women not using contraception\n* Previous organ transplant\n* Hypersensitivity to sulfur","ALL",{"count":55,"type":56},20,"ESTIMATED","INTERVENTIONAL",[59],"PHASE1","This trial will study the safety and efficacy of instillation of cultured allogeneic adult umbilical cord derived mesenchymal stem cell exosomes for the treatment of Trigeminal Neuralgia.",[62,63],"Peripheral Neuropathy","Trigeminal Neuralgia",[62,63,65],"stem cell treatment","2025-04-15",{"date":68,"type":69},"2025-04-17","ACTUAL",{"date":71,"type":69},"2022-09-09",{"date":73,"type":56},"2026-01",{"name":5,"class":6},1]