[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100235998":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":36,"responsibleParty":130,"collaborators":20,"id":133,"slug":134,"hasResults":135,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":20,"eligibilityCriteria":139,"healthyVolunteers":135,"sex":140,"minAge":20,"maxAge":20,"enrollmentInfo":141,"targetDuration":20,"studyType":144,"phases":145,"briefSummary":148,"conditions":149,"keywords":151,"overallStatus":39,"whyStopped":20,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":163},{"fullName":5,"class":6},"CHU de Quebec-Universite Laval","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment (SASS)","EXPERIMENTAL","Phase A: All patients will receive both Self assembled skin substitute (SASS) and Split-thickness autograft (paired samples sites A+ B). \u002F\u002F Phase B: All patients will receive Self assembled skin subsitute (SASS)",[13],"Biological: Self assembled skin substitute (SASS)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BIOLOGICAL","Self assembled skin substitute (SASS)","All patients in Phase B will receive Self assembled skin substitute (SASS)",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Veronique J Moulin, PhD","CHU de Quebec","PRINCIPAL_INVESTIGATOR",[27,32],{"name":23,"role":28,"phone":29,"phoneExt":30,"email":31},"CONTACT","418-525-4444","61715","veronique.moulin@fmed.ulaval.ca",{"name":33,"role":28,"phone":29,"phoneExt":34,"email":35},"Lucie Germain, PhD","61696","lucie.germain@fmed.ulaval.ca",[37,54,66,79,92,105,118],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Foothill Medcial Centre","RECRUITING","Calgary","Alberta","T2N 2T9","Canada","CA",{"type":46,"coordinates":47},"Point",[48,49],-114.08529,51.05011,{"lat":49,"lon":48},[52],{"name":53,"role":28,"phone":20,"phoneExt":20,"email":20},"Vincent Gabriel, MD",{"facility":55,"status":39,"city":56,"state":41,"zip":57,"country":43,"countryCode":44,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Mackenzie Health Science's Centre","Edmonton","T6G 2B7",{"type":46,"coordinates":59},[60,61],-113.46871,53.55014,{"lat":61,"lon":60},[64],{"name":65,"role":28,"phone":20,"phoneExt":20,"email":20},"Edward Tredget, MD",{"facility":67,"status":39,"city":68,"state":69,"zip":70,"country":43,"countryCode":44,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"BC Children's Hospital Plastic Surgery Clinic","Vancouver","British Columbia","V6H 3V4",{"type":46,"coordinates":72},[73,74],-123.11934,49.24966,{"lat":74,"lon":73},[77],{"name":78,"role":28,"phone":20,"phoneExt":20,"email":20},"Sally Hynes, MD",{"facility":80,"status":39,"city":81,"state":82,"zip":83,"country":43,"countryCode":44,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Winnipeg Health Science Center","Winnipeg","Manitoba","R3A 1R9",{"type":46,"coordinates":85},[86,87],-97.14704,49.8844,{"lat":87,"lon":86},[90],{"name":91,"role":28,"phone":20,"phoneExt":20,"email":20},"Sarvesh Logsetty, MD",{"facility":93,"status":39,"city":94,"state":95,"zip":96,"country":43,"countryCode":44,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Hospital for Sick Children (Sickkids)","Toronto","Ontario","M5G 1X8",{"type":46,"coordinates":98},[99,100],-79.39864,43.70643,{"lat":100,"lon":99},[103],{"name":104,"role":28,"phone":20,"phoneExt":20,"email":20},"Joel Fish, MD",{"facility":106,"status":39,"city":107,"state":108,"zip":109,"country":43,"countryCode":44,"cosmosGeoPoint":110,"geoPoint":114,"contacts":115},"Hôpital Sainte Justine","Montreal","Quebec","H3T 1C5",{"type":46,"coordinates":111},[112,113],-73.58781,45.50884,{"lat":113,"lon":112},[116],{"name":117,"role":28,"phone":20,"phoneExt":20,"email":20},"Patricia Bortoluzzi, MD",{"facility":119,"status":39,"city":120,"state":108,"zip":121,"country":43,"countryCode":44,"cosmosGeoPoint":122,"geoPoint":126,"contacts":127},"CHU de Québec - Unité des grands brûlés","Québec","G1J 1Z4",{"type":46,"coordinates":123},[124,125],-71.21454,46.81228,{"lat":125,"lon":124},[128],{"name":129,"role":28,"phone":20,"phoneExt":20,"email":20},"Chanel Beaudoin-Cloutier, MD",{"type":25,"investigatorFullName":131,"investigatorTitle":132,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Veronique Moulin","Researcher","100235998","phase-1-sass-2--self-assembled-skin-substitute-for-the-autologous-treatment-of-severe-burn-wounds-in-acute-stage-of-burn-trauma-100235998",false,"NCT02350205","SASS 2 : Self Assembled Skin Substitute for the Autologous Treatment of Severe Burn Wounds in Acute Stage of Burn Trauma","SASS 2 : Self Assembled Skin Substitute for the Autologous Treatment of Severe Burn Wounds in Acute Stage of Burn Trauma.","Inclusion Criteria:\n\n* Deep second degree burns or third degree burns over 50% TBSA (Total body surface area) at time of recruitment or as determined by the surgeon;\n* Limited availability of donor sites for autografts;\n* Consent obtained by the participant or by the appropriate representative in case of inapt prospective participants or minors.\n\nExclusion Criteria:\n\n* Skin grafting needed only on the face, hands, feet, ears or genital area;\n* Connective tissue diseases;\n* Hypersensitivity to bovine proteins;\n* Coagulation disorders prior being burned;\n* Immunodeficiency prior being burned;\n* Uncontrolled diabetes prior being burned;\n* Permanent wound coverage before SASS grafts are ready;","ALL",{"count":142,"type":143},52,"ESTIMATED","INTERVENTIONAL",[146,147],"PHASE1","PHASE2","This clinical trial is designed to assess the safety, effectiveness and benefits of Self Assembled Skin Substitute SASS grafts as a permanent skin replacement for the treatment of full-thickness burn wounds that require permanent coverage where the availability of donor sites is limited.",[150],"Burns",[152,150,153],"Burn wounds","Skin substitute","2025-07-22",{"date":156,"type":157},"2025-07-25","ACTUAL",{"date":159,"type":157},"2015-12",{"date":161,"type":143},"2029-01",{"name":5,"class":6},7]