[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100512190":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":38,"responsibleParty":51,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":77,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Duloxetine group (Group D)","EXPERIMENTAL","patients received oral duloxetine 60 mg 2 hours just before operation.",[13],"Drug: Duloxetine 60 MG",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group (Group C)","PLACEBO_COMPARATOR","patients received an identical placebo pill 2 hours just before operation.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Duloxetine 60 MG","Patients will recieve 2-hour preoperative duloxetine",[15,9],null,[27],{"name":28,"affiliation":29,"role":30},"Amira Hassan Ahmed, resident","Faculty of medecine,assiut,Egypt","PRINCIPAL_INVESTIGATOR",[32,36],{"name":28,"role":33,"phone":34,"phoneExt":25,"email":35},"CONTACT","+201004387008","ah3421515@gmail.com",{"name":28,"role":33,"phone":34,"phoneExt":25,"email":37},"www.gaza90@yahoo.com",[39],{"facility":40,"status":25,"city":41,"state":25,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":25},"Faculty of medicine","Asyut","71515","Egypt","EG",{"type":46,"coordinates":47},"Point",[48,49],31.18368,27.18096,{"lat":49,"lon":48},{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Amira Hassan Ahmed Ali","Egypt , Assiut governorate.","100512190","phase-1-the-effect-of-preoperative-duloxetine-on-the-occurance-of-postoperative-delirium-in-patients-undergoing-cancer-surgery-100512190",false,"NCT05949229","The Effect of Preoperative Duloxetine on the Occurance of Postoperative Delirium in Patients Undergoing Cancer Surgery.","The Effect of Preoperative Duloxetine on the Occurance of Postoperative Delirium in Patients Undergoing Cancer Surgery .","Inclusion Criteria:\n\n* All patients will sign an informed consent prior to inclusion in the study.\n* Adult patients with ASA class I-III, undergoing cancer surgery.\n\nExclusion Criteria:\n\n* Patients with pre-existing neuro- cognitive dysfunction.\n* Documented signs of dementia after psychiatric evaluations.\n* Language barriers or deafness.\n* Psychosis stroke, meningitis, or brain tumors","ALL","20 Years","80 Years",{"count":66,"type":67},42,"ESTIMATED","INTERVENTIONAL",[70,71],"PHASE1","PHASE2","This is prospective double-blinded placebo-randomized controlled trial that aims to compare the effect of preoperative administration of oral duloxetine 60 mg on decreasing the incidence of postoperative delirium in cancer patients undergoing surgery.",[74],"Post Operative Delirium",[76],"Duloxetine, POD, postoperative dilrium","NOT_YET_RECRUITING","2023-07-10",{"date":80,"type":81},"2023-07-17","ACTUAL",{"date":83,"type":67},"2023-08",{"date":85,"type":67},"2026-12",{"name":53,"class":6},1]